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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF350

Z-value: 0.45

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_52490113-0.374.7e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_327171 0.23 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr19_-_4535233 0.18 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr13_-_99738867 0.16 ENST00000427887.1
DOCK9
dedicator of cytokinesis 9
chr11_+_48002279 0.16 ENST00000534219.1
ENST00000527952.1
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr17_-_48207115 0.15 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr11_-_112034803 0.13 ENST00000528832.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr17_-_18950310 0.12 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr12_+_54519842 0.11 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chr1_+_204494618 0.11 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr11_+_48002076 0.10 ENST00000418331.2
ENST00000440289.2
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr12_+_113376157 0.10 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr6_+_32936942 0.10 ENST00000496118.2
BRD2
bromodomain containing 2
chr16_-_46864955 0.10 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr8_-_12612962 0.09 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr2_+_238600788 0.09 ENST00000289175.6
ENST00000244815.5
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr3_+_113775594 0.08 ENST00000479882.1
ENST00000493014.1
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr3_-_113775328 0.08 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
KIAA1407
chr11_-_112034780 0.08 ENST00000524595.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr3_-_155524049 0.08 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr12_+_113376249 0.08 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr3_+_140947563 0.08 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr19_+_57050317 0.08 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr9_+_34992846 0.08 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr20_+_44035847 0.07 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_68671244 0.07 ENST00000567045.1
ENST00000450904.2
MRPL21
mitochondrial ribosomal protein L21
chr11_-_112034831 0.07 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr16_+_4526341 0.07 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
HMOX2
heme oxygenase (decycling) 2
chr1_-_98510843 0.07 ENST00000413670.2
ENST00000538428.1
MIR137HG
MIR137 host gene (non-protein coding)
chr17_+_68165657 0.07 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr9_-_99616642 0.07 ENST00000478850.1
ENST00000481138.1
ZNF782
zinc finger protein 782
chr4_+_6784401 0.06 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr15_-_57210769 0.06 ENST00000559000.1
ZNF280D
zinc finger protein 280D
chr2_-_219925189 0.06 ENST00000295731.6
IHH
indian hedgehog
chr16_+_67282853 0.06 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr17_+_46985823 0.06 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr4_-_99578789 0.06 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr20_+_19738300 0.05 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chrX_-_134232630 0.05 ENST00000535837.1
ENST00000433425.2
LINC00087
long intergenic non-protein coding RNA 87
chr3_+_113775576 0.05 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr2_-_241759622 0.05 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr4_-_99578776 0.05 ENST00000515287.1
TSPAN5
tetraspanin 5
chr11_-_68671264 0.05 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr10_-_12084770 0.05 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chrX_+_56259316 0.05 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr10_-_120938303 0.05 ENST00000356951.3
ENST00000298510.2
PRDX3
peroxiredoxin 3
chr16_-_74734672 0.05 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr20_+_44035200 0.05 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_-_204654481 0.04 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr11_+_8932828 0.04 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
AKIP1
A kinase (PRKA) interacting protein 1
chr14_+_76618242 0.04 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr11_-_45687128 0.04 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr4_-_174255400 0.04 ENST00000506267.1
HMGB2
high mobility group box 2
chr17_-_6554877 0.04 ENST00000225728.3
ENST00000575197.1
MED31
mediator complex subunit 31
chr15_-_65477637 0.04 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr2_-_9143786 0.04 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr4_-_174255536 0.04 ENST00000446922.2
HMGB2
high mobility group box 2
chr2_-_70780770 0.04 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr4_+_108911036 0.04 ENST00000505878.1
HADH
hydroxyacyl-CoA dehydrogenase
chr11_-_63381925 0.04 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr3_+_14219858 0.04 ENST00000306024.3
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_63381823 0.04 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr11_-_9113137 0.04 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr2_-_21266935 0.04 ENST00000233242.1
APOB
apolipoprotein B
chr1_+_204797749 0.04 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr11_-_7041466 0.03 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr1_-_247094628 0.03 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1
AT hook containing transcription factor 1
chr3_+_50229037 0.03 ENST00000232461.3
ENST00000433068.1
GNAT1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr18_+_77155942 0.03 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr4_-_120133661 0.03 ENST00000503243.1
ENST00000326780.3
RP11-455G16.1
Uncharacterized protein
chr1_-_200379180 0.03 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_+_156611960 0.03 ENST00000361588.5
BCAN
brevican
chr19_+_35645817 0.03 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_49351148 0.03 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr11_-_64511575 0.03 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_64511789 0.03 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_7041677 0.03 ENST00000299481.4
NLRP14
NLR family, pyrin domain containing 14
chr3_-_151176497 0.03 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr13_-_96329048 0.03 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1
DNAJC3 antisense RNA 1 (head to head)
chr17_-_62340581 0.03 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr1_-_46089639 0.03 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chr9_-_92051391 0.03 ENST00000420681.2
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr10_+_94821021 0.03 ENST00000285949.5
CYP26C1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr4_+_108910870 0.03 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chr20_-_35374456 0.03 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3
NDRG family member 3
chr16_-_74734742 0.03 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr13_+_50202435 0.03 ENST00000282026.1
ARL11
ADP-ribosylation factor-like 11
chr16_+_31225337 0.03 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr21_-_38639813 0.02 ENST00000309117.6
ENST00000398998.1
DSCR3
Down syndrome critical region gene 3
chr3_-_128902729 0.02 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr3_-_128902759 0.02 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr12_-_93323013 0.02 ENST00000322349.8
EEA1
early endosome antigen 1
chr5_-_107717058 0.02 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr19_+_35645618 0.02 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr16_-_46865047 0.02 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr5_+_42423872 0.02 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr16_+_69600058 0.02 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr9_-_92051354 0.02 ENST00000418828.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr16_+_14802801 0.02 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr5_+_176514413 0.02 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr8_+_22414182 0.02 ENST00000524057.1
SORBS3
sorbin and SH3 domain containing 3
chr11_+_8932654 0.02 ENST00000299576.5
ENST00000309377.4
ENST00000309357.4
AKIP1
A kinase (PRKA) interacting protein 1
chrX_-_17878827 0.02 ENST00000360011.1
RAI2
retinoic acid induced 2
chr4_-_174256276 0.02 ENST00000296503.5
HMGB2
high mobility group box 2
chr6_+_32937083 0.02 ENST00000456339.1
BRD2
bromodomain containing 2
chr15_+_42694573 0.02 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr16_+_71879861 0.02 ENST00000427980.2
ENST00000568581.1
ATXN1L
IST1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr17_+_19030782 0.02 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr14_+_73603126 0.02 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr2_-_70780572 0.02 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr11_-_64612041 0.02 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr19_+_2977444 0.02 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr9_+_19408999 0.02 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr16_-_46865286 0.02 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr4_+_120133791 0.01 ENST00000274030.6
USP53
ubiquitin specific peptidase 53
chr12_-_53228079 0.01 ENST00000330553.5
KRT79
keratin 79
chr8_-_119124045 0.01 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr12_-_109219937 0.01 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr6_+_36973406 0.01 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr19_+_39903185 0.01 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr2_-_157198860 0.01 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_-_118753566 0.01 ENST00000491903.1
IGSF11
immunoglobulin superfamily, member 11
chr11_-_6790286 0.01 ENST00000338569.2
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr3_-_118753716 0.01 ENST00000393775.2
IGSF11
immunoglobulin superfamily, member 11
chr3_-_14220068 0.01 ENST00000449060.2
ENST00000511155.1
XPC
xeroderma pigmentosum, complementation group C
chr13_-_37633567 0.01 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr19_-_14628234 0.01 ENST00000595139.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr21_-_30365136 0.01 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr15_+_57210961 0.01 ENST00000557843.1
TCF12
transcription factor 12
chr13_+_96329381 0.01 ENST00000602402.1
ENST00000376795.6
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr3_-_118753792 0.01 ENST00000480431.1
IGSF11
immunoglobulin superfamily, member 11
chr12_+_8185288 0.01 ENST00000162391.3
FOXJ2
forkhead box J2
chr1_-_200379129 0.01 ENST00000367353.1
ZNF281
zinc finger protein 281
chr10_-_97175444 0.01 ENST00000486141.2
SORBS1
sorbin and SH3 domain containing 1
chr20_+_4666882 0.01 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr17_-_8093471 0.01 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr1_+_173446405 0.00 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr1_-_200379104 0.00 ENST00000367352.3
ZNF281
zinc finger protein 281
chr15_+_57210818 0.00 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr2_-_166650700 0.00 ENST00000422973.1
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_202792385 0.00 ENST00000549576.1
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr3_-_11623804 0.00 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr2_+_235860616 0.00 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr1_+_29213678 0.00 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr17_-_18950950 0.00 ENST00000284154.5
GRAP
GRB2-related adaptor protein
chr17_+_68071389 0.00 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_68071458 0.00 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_6554971 0.00 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr17_-_79881408 0.00 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr2_-_106810742 0.00 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.3 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)