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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF691

Z-value: 0.66

Motif logo

Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ENSG00000164011.13 zinc finger protein 691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF691hg19_v2_chr1_+_43312258_43312310-0.483.4e-01Click!

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_40516560 0.44 ENST00000513473.1
RNA binding motif protein 47
chr3_+_177534653 0.39 ENST00000436078.1
RP11-91K9.1
chr19_+_40877583 0.38 ENST00000596470.1
phospholipase D family, member 3
chr10_+_4828815 0.38 ENST00000533295.1
aldo-keto reductase family 1, member E2
chr22_+_23264766 0.32 ENST00000390331.2
immunoglobulin lambda constant 7
chr11_+_102188272 0.30 ENST00000532808.1
baculoviral IAP repeat containing 3
chr20_-_1317555 0.28 ENST00000537552.1
HCG2043693; Uncharacterized protein
chr22_-_32058416 0.28 ENST00000439502.2
phosphatidylserine decarboxylase
chr19_-_5903714 0.28 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr15_-_74726283 0.27 ENST00000543145.2
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr15_-_40398812 0.27 ENST00000561360.1
Bcl2 modifying factor
chr15_-_86338100 0.27 ENST00000536947.1
kelch-like family member 25
chr8_-_145159083 0.26 ENST00000398712.2
SHANK-associated RH domain interactor
chr8_-_144679264 0.26 ENST00000531953.1
ENST00000526133.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr3_-_107596910 0.25 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr19_+_40873617 0.24 ENST00000599353.1
phospholipase D family, member 3
chr9_-_135754164 0.24 ENST00000298545.3
adenylate kinase 8
chr2_-_203736452 0.22 ENST00000419460.1
islet cell autoantigen 1,69kDa-like
chr17_+_38121772 0.21 ENST00000577447.1
gasdermin A
chr17_-_61777459 0.21 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr12_+_120502441 0.21 ENST00000446727.2
coiled-coil domain containing 64
chr16_+_810728 0.19 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
mesothelin
chr5_+_53686658 0.19 ENST00000512618.1
long intergenic non-protein coding RNA 1033
chr14_+_55033815 0.19 ENST00000554335.1
sterile alpha motif domain containing 4A
chr8_+_27169138 0.19 ENST00000522338.1
protein tyrosine kinase 2 beta
chr21_-_37852359 0.18 ENST00000399137.1
ENST00000399135.1
claudin 14
chr8_-_102181718 0.18 ENST00000565617.1
KB-1460A1.5
chr9_+_135754263 0.17 ENST00000356311.5
ENST00000350499.6
chromosome 9 open reading frame 9
chr21_+_44866471 0.16 ENST00000448049.1
long intergenic non-protein coding RNA 319
chr1_+_26856236 0.16 ENST00000374168.2
ENST00000374166.4
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_+_3596168 0.15 ENST00000302006.3
iroquois homeobox 1
chr20_-_2644832 0.14 ENST00000380851.5
ENST00000380843.4
isocitrate dehydrogenase 3 (NAD+) beta
chr6_+_31021225 0.14 ENST00000565192.1
ENST00000562344.1
HLA complex group 22
chrX_-_153775760 0.14 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
glucose-6-phosphate dehydrogenase
chr15_-_39486510 0.14 ENST00000560743.1
RP11-265N7.1
chr5_-_179107975 0.13 ENST00000376974.4
chibby homolog 3 (Drosophila)
chr10_+_104678032 0.13 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr8_-_123793048 0.13 ENST00000607710.1
RP11-44N11.2
chr2_+_202098203 0.13 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
caspase 8, apoptosis-related cysteine peptidase
chr5_-_176889381 0.13 ENST00000393563.4
ENST00000512501.1
drebrin 1
chr1_-_33647267 0.13 ENST00000291416.5
tripartite motif containing 62
chr19_-_59023348 0.13 ENST00000601355.1
ENST00000263093.2
solute carrier family 27 (fatty acid transporter), member 5
chr2_-_74669009 0.12 ENST00000272430.5
rhotekin
chr17_-_80797886 0.12 ENST00000572562.1
zinc finger protein 750
chr3_+_9850199 0.12 ENST00000452597.1
tubulin tyrosine ligase-like family, member 3
chr14_+_55034330 0.12 ENST00000251091.5
sterile alpha motif domain containing 4A
chr22_-_32058166 0.12 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr17_-_73840614 0.11 ENST00000586108.1
unc-13 homolog D (C. elegans)
chr8_+_32579321 0.11 ENST00000522402.1
neuregulin 1
chr15_+_84908573 0.11 ENST00000424966.1
ENST00000422563.2
golgin A6 family-like 4
chrX_+_153672468 0.11 ENST00000393600.3
family with sequence similarity 50, member A
chr11_-_65655906 0.11 ENST00000533045.1
ENST00000338369.2
ENST00000357519.4
fibroblast growth factor (acidic) intracellular binding protein
chrX_+_153775821 0.10 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr4_-_120243545 0.10 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr2_-_203736334 0.10 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
islet cell autoantigen 1,69kDa-like
chr17_+_80416482 0.10 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr15_-_49912944 0.10 ENST00000559905.1
family with sequence similarity 227, member B
chr8_-_119964434 0.10 ENST00000297350.4
tumor necrosis factor receptor superfamily, member 11b
chr8_+_27168988 0.10 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr19_-_893200 0.09 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
mediator complex subunit 16
chr7_-_84569561 0.09 ENST00000439105.1
AC074183.4
chr17_+_36908984 0.09 ENST00000225426.4
ENST00000579088.1
proteasome (prosome, macropain) subunit, beta type, 3
chr14_+_103388976 0.09 ENST00000299155.5
amnion associated transmembrane protein
chr8_-_144679296 0.09 ENST00000317198.6
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr19_-_15560730 0.09 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr1_+_145516560 0.08 ENST00000537888.1
peroxisomal biogenesis factor 11 beta
chr2_+_68962014 0.08 ENST00000467265.1
Rho GTPase activating protein 25
chr9_+_139553306 0.08 ENST00000371699.1
EGF-like-domain, multiple 7
chr16_+_53738053 0.08 ENST00000394647.3
fat mass and obesity associated
chr8_-_144679532 0.08 ENST00000534380.1
ENST00000533494.1
ENST00000531218.1
ENST00000526340.1
ENST00000533204.1
ENST00000532400.1
ENST00000529516.1
ENST00000534377.1
ENST00000531621.1
ENST00000530191.1
ENST00000524900.1
ENST00000526838.1
ENST00000531931.1
ENST00000534475.1
ENST00000442189.2
ENST00000524624.1
ENST00000532596.1
ENST00000529832.1
ENST00000530306.1
ENST00000530545.1
ENST00000525261.1
ENST00000534804.1
ENST00000528303.1
ENST00000528610.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr11_+_64949899 0.08 ENST00000531068.1
ENST00000527699.1
ENST00000533909.1
ENST00000527323.1
calpain 1, (mu/I) large subunit
chr15_-_100258029 0.08 ENST00000378904.2
DKFZP779J2370
chr6_-_144329531 0.08 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr18_+_12947126 0.07 ENST00000592170.1
SEH1-like (S. cerevisiae)
chr22_-_43539346 0.07 ENST00000327555.5
ENST00000290429.6
malonyl CoA:ACP acyltransferase (mitochondrial)
chr12_+_27619743 0.07 ENST00000298876.4
ENST00000416383.1
single-pass membrane protein with coiled-coil domains 2
chr8_+_145294015 0.07 ENST00000544576.1
maestro heat-like repeat family member 1
chr16_-_1821496 0.07 ENST00000564628.1
ENST00000563498.1
NME/NM23 nucleoside diphosphate kinase 3
chr9_+_139847347 0.07 ENST00000371632.3
lipocalin 12
chr20_-_33735070 0.07 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chrX_-_153775047 0.06 ENST00000433845.1
ENST00000439227.1
glucose-6-phosphate dehydrogenase
chr1_+_11994715 0.06 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr8_+_32579341 0.06 ENST00000519240.1
ENST00000539990.1
neuregulin 1
chr20_-_45976816 0.06 ENST00000441977.1
zinc finger, MYND-type containing 8
chr1_+_28199047 0.06 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
thymocyte selection associated family member 2
chr5_+_7396141 0.06 ENST00000338316.4
adenylate cyclase 2 (brain)
chr3_-_194968576 0.06 ENST00000429994.1
xyloside xylosyltransferase 1
chr17_+_80416609 0.05 ENST00000577410.1
nuclear prelamin A recognition factor
chr15_-_26108355 0.05 ENST00000356865.6
ATPase, class V, type 10A
chr17_+_37026106 0.05 ENST00000318008.6
LIM and SH3 protein 1
chr4_+_657485 0.05 ENST00000471824.2
phosphodiesterase 6B, cGMP-specific, rod, beta
chr1_-_233431458 0.05 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr10_-_99258135 0.05 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr17_-_3417062 0.05 ENST00000570318.1
ENST00000541913.1
spermatogenesis associated 22
chr2_+_68961934 0.05 ENST00000409202.3
Rho GTPase activating protein 25
chr3_-_157251383 0.05 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr11_-_133826852 0.04 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr1_-_148202536 0.04 ENST00000544708.1
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr17_-_41738931 0.04 ENST00000329168.3
ENST00000549132.1
mesenchyme homeobox 1
chr6_-_90529418 0.04 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1, midasin homolog (yeast)
chr6_+_31553901 0.04 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr12_-_10605929 0.04 ENST00000347831.5
ENST00000359151.3
killer cell lectin-like receptor subfamily C, member 1
chr6_+_151186554 0.04 ENST00000367321.3
ENST00000367307.4
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_36619771 0.04 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
recombination activating gene 2
chr19_+_50084561 0.04 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr19_+_50380917 0.04 ENST00000535102.2
TBC1 domain family, member 17
chr2_+_68961905 0.03 ENST00000295381.3
Rho GTPase activating protein 25
chr12_-_51717948 0.03 ENST00000267012.4
bridging integrator 2
chr17_-_73839792 0.03 ENST00000590762.1
unc-13 homolog D (C. elegans)
chr12_-_109221160 0.03 ENST00000326470.5
slingshot protein phosphatase 1
chr17_+_80416050 0.03 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr17_+_37026284 0.03 ENST00000433206.2
ENST00000435347.3
LIM and SH3 protein 1
chr12_-_51717922 0.03 ENST00000452142.2
bridging integrator 2
chr3_-_46037299 0.03 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr12_-_51717875 0.03 ENST00000604560.1
bridging integrator 2
chrX_-_62571187 0.03 ENST00000335144.3
spindlin family, member 4
chr7_-_143059780 0.03 ENST00000409578.1
ENST00000409346.1
family with sequence similarity 131, member B
chr10_+_104678102 0.03 ENST00000433628.2
cyclin M2
chr6_+_31553978 0.02 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr9_+_116267536 0.02 ENST00000374136.1
regulator of G-protein signaling 3
chr15_+_89402148 0.02 ENST00000560601.1
aggrecan
chr20_+_62887081 0.02 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr19_-_17932314 0.02 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
insulin-like 3 (Leydig cell)
chr2_+_106468204 0.02 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr12_-_51718436 0.02 ENST00000544402.1
bridging integrator 2
chr3_+_37493590 0.02 ENST00000422441.1
integrin, alpha 9
chr10_-_4720301 0.02 ENST00000449712.1
long intergenic non-protein coding RNA 704
chr17_+_75401152 0.02 ENST00000585930.1
septin 9
chr6_-_27279949 0.02 ENST00000444565.1
ENST00000377451.2
POM121 transmembrane nucleoporin-like 2
chr16_-_11492366 0.02 ENST00000595360.1
Protein LOC388210
chr17_-_73840415 0.02 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
unc-13 homolog D (C. elegans)
chr1_+_178482212 0.02 ENST00000319416.2
ENST00000258298.2
ENST00000367643.3
ENST00000367642.3
testis expressed 35
chr7_+_7811992 0.02 ENST00000406829.1
RPA3 antisense RNA 1
chr1_+_39796810 0.02 ENST00000289893.4
microtubule-actin crosslinking factor 1
chrX_+_102469997 0.02 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr11_-_64889529 0.01 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr6_-_159240415 0.01 ENST00000367075.3
ezrin
chr14_-_74296806 0.01 ENST00000555539.1
RP5-1021I20.2
chr17_-_38821373 0.01 ENST00000394052.3
keratin 222
chr1_+_90308981 0.01 ENST00000527156.1
leucine rich repeat containing 8 family, member D
chr3_+_33331156 0.01 ENST00000542085.1
F-box and leucine-rich repeat protein 2
chr5_-_131347501 0.01 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr22_-_45608237 0.01 ENST00000492273.1
KIAA0930
chr1_-_155232221 0.00 ENST00000355379.3
secretory carrier membrane protein 3
chr19_-_9649303 0.00 ENST00000253115.2
zinc finger protein 426
chr15_-_58571445 0.00 ENST00000558231.1
aldehyde dehydrogenase 1 family, member A2
chr7_+_134576317 0.00 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr17_+_45286387 0.00 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0002432 granuloma formation(GO:0002432)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway