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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF740_ZNF219

Z-value: 0.81

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Transcription factors associated with ZNF740_ZNF219

Gene Symbol Gene ID Gene Info
ENSG00000139651.9 zinc finger protein 740
ENSG00000165804.11 zinc finger protein 219

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF740hg19_v2_chr12_+_53574464_535745390.612.0e-01Click!
ZNF219hg19_v2_chr14_-_21562671_21562702-0.552.6e-01Click!

Activity profile of ZNF740_ZNF219 motif

Sorted Z-values of ZNF740_ZNF219 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_110500826 0.69 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WAS protein family, member 1
chr17_-_58469591 0.68 ENST00000589335.1
ubiquitin specific peptidase 32
chr17_-_27277615 0.65 ENST00000583747.1
ENST00000584236.1
PHD finger protein 12
chr14_+_38065052 0.55 ENST00000556845.1
tetratricopeptide repeat domain 6
chr1_+_164528866 0.52 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr1_+_6845578 0.51 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr17_-_58469329 0.48 ENST00000393003.3
ubiquitin specific peptidase 32
chr2_+_149402989 0.46 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_48673465 0.45 ENST00000598938.1
ligase I, DNA, ATP-dependent
chr2_-_55277654 0.44 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr2_-_148778323 0.42 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr1_-_167906277 0.40 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr2_-_61765315 0.38 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chrX_-_119695279 0.36 ENST00000336592.6
cullin 4B
chr1_-_150208412 0.35 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_-_55277692 0.35 ENST00000394611.2
reticulon 4
chr3_-_171177852 0.34 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TRAF2 and NCK interacting kinase
chr2_-_55277436 0.34 ENST00000354474.6
reticulon 4
chr7_-_127032363 0.34 ENST00000393312.1
zinc finger protein 800
chr17_+_55334364 0.33 ENST00000322684.3
ENST00000579590.1
musashi RNA-binding protein 2
chr18_-_51750948 0.33 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr17_-_56065540 0.33 ENST00000583932.1
vascular endothelial zinc finger 1
chr14_-_54418598 0.32 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chr6_-_31869769 0.31 ENST00000375527.2
zinc finger and BTB domain containing 12
chr12_+_57522692 0.30 ENST00000554174.1
low density lipoprotein receptor-related protein 1
chr15_+_96904487 0.30 ENST00000600790.1
Uncharacterized protein
chr12_+_69004805 0.30 ENST00000541216.1
RAP1B, member of RAS oncogene family
chr8_+_26149274 0.29 ENST00000522535.1
protein phosphatase 2, regulatory subunit B, alpha
chr3_+_107243204 0.29 ENST00000456817.1
ENST00000458458.1
bobby sox homolog (Drosophila)
chr1_+_35734616 0.29 ENST00000441447.1
zinc finger, MYM-type 4
chr2_-_148778258 0.28 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr11_-_63933504 0.28 ENST00000255681.6
MACRO domain containing 1
chr2_-_174828892 0.28 ENST00000418194.2
Sp3 transcription factor
chr8_+_95653840 0.28 ENST00000520385.1
epithelial splicing regulatory protein 1
chr17_+_55333876 0.27 ENST00000284073.2
musashi RNA-binding protein 2
chr10_+_76586348 0.27 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr15_+_100106670 0.27 ENST00000559903.1
myocyte enhancer factor 2A
chr10_+_35416223 0.26 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr7_-_127032741 0.26 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
zinc finger protein 800
chr1_-_150208498 0.26 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr22_-_28197486 0.26 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr14_+_23352374 0.26 ENST00000267396.4
ENST00000536884.1
RAS (RAD and GEM)-like GTP binding 2
chr1_+_212458834 0.26 ENST00000261461.2
protein phosphatase 2, regulatory subunit B', alpha
chr1_-_98511756 0.25 ENST00000602984.1
ENST00000602852.1
MIR137 host gene (non-protein coding)
chr12_+_69004736 0.25 ENST00000545720.2
RAP1B, member of RAS oncogene family
chr12_+_21654714 0.25 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr14_-_61190754 0.24 ENST00000216513.4
SIX homeobox 4
chr2_-_148779106 0.24 ENST00000416719.1
ENST00000264169.2
origin recognition complex, subunit 4
chr2_-_61765732 0.24 ENST00000443240.1
ENST00000436018.1
exportin 1 (CRM1 homolog, yeast)
chr12_+_69004619 0.24 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr2_-_55277512 0.24 ENST00000402434.2
reticulon 4
chr3_-_88108192 0.24 ENST00000309534.6
CGG triplet repeat binding protein 1
chr15_-_71146347 0.23 ENST00000559140.2
La ribonucleoprotein domain family, member 6
chrX_+_123094672 0.23 ENST00000354548.5
ENST00000458700.1
stromal antigen 2
chr2_+_149402553 0.23 ENST00000258484.6
ENST00000409654.1
enhancer of polycomb homolog 2 (Drosophila)
chr12_-_6715808 0.23 ENST00000545584.1
chromodomain helicase DNA binding protein 4
chr15_-_60771128 0.23 ENST00000558512.1
ENST00000561114.1
NMDA receptor regulated 2
chr4_+_146402997 0.23 ENST00000512019.1
SMAD family member 1
chr4_-_140098339 0.22 ENST00000394235.2
E74-like factor 2 (ets domain transcription factor)
chr17_+_42634844 0.22 ENST00000315323.3
frizzled family receptor 2
chr17_-_66287310 0.22 ENST00000582867.1
solute carrier family 16, member 6
chr13_-_52026730 0.22 ENST00000420668.2
integrator complex subunit 6
chr17_-_6459802 0.21 ENST00000262483.8
PITPNM family member 3
chr19_+_38880695 0.21 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr17_+_46131912 0.21 ENST00000584634.1
ENST00000580050.1
nuclear factor, erythroid 2-like 1
chr8_+_120428546 0.20 ENST00000259526.3
nephroblastoma overexpressed
chr13_+_20532900 0.20 ENST00000382871.2
zinc finger, MYM-type 2
chr1_-_91487770 0.20 ENST00000337393.5
zinc finger protein 644
chr22_-_29138386 0.20 ENST00000544772.1
checkpoint kinase 2
chr18_+_72265084 0.20 ENST00000582337.1
zinc finger protein 407
chr12_+_57522439 0.20 ENST00000338962.4
low density lipoprotein receptor-related protein 1
chr15_-_60771280 0.19 ENST00000560072.1
ENST00000560406.1
ENST00000560520.1
ENST00000261520.4
ENST00000439632.1
NMDA receptor regulated 2
chr12_+_69004705 0.19 ENST00000534899.1
ENST00000453560.2
ENST00000378985.3
ENST00000540209.1
ENST00000540781.1
ENST00000535492.1
ENST00000539091.1
ENST00000542145.1
ENST00000485252.2
ENST00000541386.1
ENST00000538877.1
ENST00000543697.1
RAP1B, member of RAS oncogene family
chr5_+_133707252 0.19 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr14_+_74815116 0.19 ENST00000256362.4
vertebrae development associated
chr17_+_38278530 0.19 ENST00000398532.4
male-specific lethal 1 homolog (Drosophila)
chr11_-_85780086 0.19 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr2_+_111878483 0.19 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2-like 11 (apoptosis facilitator)
chr9_-_20622478 0.19 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_+_95653302 0.19 ENST00000423620.2
ENST00000433389.2
epithelial splicing regulatory protein 1
chr11_-_67980744 0.18 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr1_-_150208320 0.18 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_-_61697862 0.18 ENST00000398571.2
ubiquitin specific peptidase 34
chr15_-_65477637 0.18 ENST00000300107.3
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr22_+_46546406 0.18 ENST00000440343.1
ENST00000415785.1
peroxisome proliferator-activated receptor alpha
chr3_+_154797636 0.18 ENST00000481828.1
membrane metallo-endopeptidase
chr10_+_98592009 0.18 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chr1_-_150208363 0.18 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_81687197 0.18 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr1_+_6845497 0.18 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr20_+_47662805 0.17 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr15_-_43212836 0.17 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
tau tubulin kinase 2
chr17_-_47755338 0.17 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr13_+_20532848 0.17 ENST00000382874.2
zinc finger, MYM-type 2
chr11_+_85956182 0.17 ENST00000327320.4
ENST00000351625.6
ENST00000534595.1
embryonic ectoderm development
chr7_+_26241325 0.17 ENST00000456948.1
ENST00000409747.1
chromobox homolog 3
chr20_-_31071309 0.17 ENST00000326071.4
chromosome 20 open reading frame 112
chrX_-_20134990 0.17 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7 domain containing 2
chr1_+_164528616 0.17 ENST00000340699.3
pre-B-cell leukemia homeobox 1
chr2_-_208030886 0.16 ENST00000426163.1
Kruppel-like factor 7 (ubiquitous)
chr18_-_72265035 0.16 ENST00000585279.1
ENST00000580048.1
long intergenic non-protein coding RNA 909
chr1_-_211752073 0.16 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr11_-_85779971 0.16 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chrX_+_123095860 0.16 ENST00000428941.1
stromal antigen 2
chr12_-_111180644 0.16 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
protein phosphatase 1, catalytic subunit, gamma isozyme
chr17_+_1959369 0.16 ENST00000576444.1
ENST00000322941.3
hypermethylated in cancer 1
chr1_-_244013384 0.16 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr12_+_56401268 0.15 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr8_-_101734170 0.15 ENST00000522387.1
ENST00000518196.1
poly(A) binding protein, cytoplasmic 1
chr1_+_203765437 0.15 ENST00000550078.1
zinc finger, BED-type containing 6
chr12_+_6833323 0.15 ENST00000544725.1
COP9 signalosome subunit 7A
chrX_+_24167746 0.15 ENST00000428571.1
ENST00000539115.1
zinc finger protein, X-linked
chr13_+_20532807 0.15 ENST00000382869.3
ENST00000382881.3
zinc finger, MYM-type 2
chrX_+_123095546 0.15 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
stromal antigen 2
chr5_+_36876833 0.15 ENST00000282516.8
ENST00000448238.2
Nipped-B homolog (Drosophila)
chr5_+_49962495 0.15 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr2_-_101767715 0.15 ENST00000376840.4
ENST00000409318.1
TBC1 domain family, member 8 (with GRAM domain)
chr1_+_26438289 0.15 ENST00000374271.4
ENST00000374269.1
PDLIM1 interacting kinase 1 like
chrX_+_123095890 0.15 ENST00000435215.1
stromal antigen 2
chr15_+_71145578 0.14 ENST00000544974.2
ENST00000558546.1
leucine rich repeat containing 49
chr11_+_77532233 0.14 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr10_+_99344104 0.14 ENST00000555577.1
ENST00000370649.3
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr5_-_142784003 0.14 ENST00000416954.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_157291953 0.14 ENST00000310454.6
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr12_+_1100710 0.14 ENST00000589132.1
ELKS/RAB6-interacting/CAST family member 1
chr7_+_26241310 0.14 ENST00000396386.2
chromobox homolog 3
chr17_+_46131843 0.14 ENST00000577411.1
nuclear factor, erythroid 2-like 1
chr13_-_52027134 0.14 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr17_-_4269768 0.14 ENST00000396981.2
ubiquitin-conjugating enzyme E2G 1
chr6_-_30523865 0.14 ENST00000433809.1
guanine nucleotide binding protein-like 1
chr3_-_129612394 0.14 ENST00000505616.1
ENST00000426664.2
transmembrane and coiled-coil domain family 1
chr10_+_99344071 0.14 ENST00000370647.4
ENST00000370646.4
4-hydroxy-2-oxoglutarate aldolase 1
chr8_+_124429006 0.14 ENST00000522194.1
ENST00000523356.1
WDYHV motif containing 1
chr15_+_98503922 0.14 ENST00000268042.6
arrestin domain containing 4
chr1_+_167905894 0.14 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DDB1 and CUL4 associated factor 6
chr20_-_52210368 0.14 ENST00000371471.2
zinc finger protein 217
chr22_+_29168652 0.13 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chrX_-_119694538 0.13 ENST00000371322.5
cullin 4B
chr11_-_77531752 0.13 ENST00000440064.2
ENST00000528095.1
remodeling and spacing factor 1
chr17_+_46132037 0.13 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
nuclear factor, erythroid 2-like 1
chr4_-_102267953 0.13 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_7222233 0.13 ENST00000436587.2
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr2_+_149402009 0.13 ENST00000457184.1
enhancer of polycomb homolog 2 (Drosophila)
chrX_+_12993336 0.13 ENST00000380635.1
thymosin beta 4, X-linked
chr5_-_56247935 0.13 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
mesoderm induction early response 1, family member 3
chr1_-_91487013 0.13 ENST00000347275.5
ENST00000370440.1
zinc finger protein 644
chr19_-_36233332 0.13 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGF-like family receptor 1
chr3_-_171178157 0.13 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TRAF2 and NCK interacting kinase
chr1_+_164529004 0.13 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
pre-B-cell leukemia homeobox 1
chr3_-_52002194 0.13 ENST00000466412.1
poly(rC) binding protein 4
chr4_+_38665810 0.13 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr11_-_77531858 0.13 ENST00000360355.2
remodeling and spacing factor 1
chr20_-_271009 0.13 ENST00000382369.5
chromosome 20 open reading frame 96
chr13_-_45010939 0.12 ENST00000261489.2
TSC22 domain family, member 1
chr4_-_99850243 0.12 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr2_+_26568965 0.12 ENST00000260585.7
ENST00000447170.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr6_+_114178512 0.12 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr13_+_100741269 0.12 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
propionyl CoA carboxylase, alpha polypeptide
chr2_-_224702201 0.12 ENST00000446015.2
adaptor-related protein complex 1, sigma 3 subunit
chr17_+_57297807 0.12 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
glycerophosphodiester phosphodiesterase domain containing 1
chr10_+_21823079 0.12 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr16_-_49890016 0.12 ENST00000563137.2
zinc finger protein 423
chrX_-_20134713 0.12 ENST00000452324.3
MAP7 domain containing 2
chr11_+_77532155 0.12 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
adipogenesis associated, Mth938 domain containing
chr14_+_57857262 0.12 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_-_48132924 0.12 ENST00000403359.3
F-box protein 11
chr11_-_46142615 0.12 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr7_+_23145347 0.12 ENST00000322231.7
kelch-like family member 7
chr19_-_41222775 0.12 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
aarF domain containing kinase 4
chr11_-_46142505 0.12 ENST00000524497.1
ENST00000418153.2
PHD finger protein 21A
chr8_-_124428569 0.11 ENST00000521903.1
ATPase family, AAA domain containing 2
chr12_-_6716569 0.11 ENST00000544040.1
ENST00000545942.1
chromodomain helicase DNA binding protein 4
chr5_+_67511524 0.11 ENST00000521381.1
ENST00000521657.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_53846594 0.11 ENST00000550192.1
poly(rC) binding protein 2
chr14_-_53619816 0.11 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD domain containing 1
chr12_-_21654479 0.11 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RecQ protein-like (DNA helicase Q1-like)
chr11_-_77532050 0.11 ENST00000308488.6
remodeling and spacing factor 1
chr18_-_32924372 0.11 ENST00000261332.6
ENST00000399061.3
zinc finger protein 24
chr7_-_79082867 0.11 ENST00000419488.1
ENST00000354212.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_150721570 0.11 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
autophagy related 9B
chr15_+_100106244 0.11 ENST00000557942.1
myocyte enhancer factor 2A
chr1_-_149908217 0.11 ENST00000369140.3
myotubularin related protein 11
chr18_+_21594585 0.11 ENST00000317571.3
tetratricopeptide repeat domain 39C
chr1_-_167906020 0.11 ENST00000458574.1
mitochondrial pyruvate carrier 2
chr12_+_100661156 0.11 ENST00000360820.2
SCY1-like 2 (S. cerevisiae)
chr8_+_95653427 0.11 ENST00000454170.2
epithelial splicing regulatory protein 1
chr5_-_142783694 0.11 ENST00000394466.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_181845843 0.11 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr3_+_20081515 0.11 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr15_-_71146460 0.11 ENST00000344870.4
La ribonucleoprotein domain family, member 6
chr2_-_172017393 0.10 ENST00000442919.2
tousled-like kinase 1
chr9_-_14313893 0.10 ENST00000380921.3
ENST00000380959.3
nuclear factor I/B
chr5_+_137688285 0.10 ENST00000314358.5
lysine (K)-specific demethylase 3B
chr1_+_28995231 0.10 ENST00000373816.1
glucocorticoid modulatory element binding protein 1
chr8_+_95653373 0.10 ENST00000358397.5
epithelial splicing regulatory protein 1
chr1_+_178694362 0.10 ENST00000367634.2
Ral GEF with PH domain and SH3 binding motif 2
chr15_+_100106155 0.10 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
myocyte enhancer factor 2A
chr6_+_73331520 0.10 ENST00000342056.2
ENST00000355194.4
potassium voltage-gated channel, KQT-like subfamily, member 5
chr2_-_202316169 0.10 ENST00000430254.1
trafficking protein, kinesin binding 2
chr17_+_42385927 0.10 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 1.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0071893 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.2 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.4 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.1 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 1.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) regulation of penile erection(GO:0060405)
0.0 0.4 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.0 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.0 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:1990868 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0035822 gene conversion(GO:0035822)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) regulation of tolerance induction dependent upon immune response(GO:0002652)
0.0 0.0 GO:0051413 response to cortisone(GO:0051413)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.0 0.0 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.0 GO:0075341 host cell PML body(GO:0075341)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.0 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins