Motif ID: Aire

Z-value: 0.978


Transcription factors associated with Aire:

Gene SymbolEntrez IDGene Name
Aire ENSMUSG00000000731.9 Aire



Activity profile for motif Aire.

activity profile for motif Aire


Sorted Z-values histogram for motif Aire

Sorted Z-values for motif Aire



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_61185558 58.851 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr13_-_110280103 11.086 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr8_+_69808672 9.647 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr12_-_78983476 8.650 ENSMUST00000070174.7
Tmem229b
transmembrane protein 229B
chr5_-_84417359 7.837 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr10_+_123264076 7.628 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr3_-_116968969 7.128 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr2_+_55435918 5.636 ENSMUST00000067101.3
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr18_+_37400845 5.003 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr9_-_53610329 4.919 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr7_-_127895578 4.642 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr16_+_36875119 4.416 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr14_+_76476913 4.415 ENSMUST00000140251.2
Tsc22d1
TSC22 domain family, member 1
chr7_+_60155538 4.066 ENSMUST00000057611.4
Gm7367
predicted pseudogene 7367
chr2_-_134644079 4.001 ENSMUST00000110119.1
Tmx4
thioredoxin-related transmembrane protein 4
chr18_+_37725706 3.945 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr10_+_86021961 3.874 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr19_-_28963863 3.627 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr16_-_91618986 2.683 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr10_-_130280218 2.665 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr10_-_81014902 2.649 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
Gng7


guanine nucleotide binding protein (G protein), gamma 7


chr7_+_28863831 2.636 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chr8_+_64947177 2.630 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr5_+_24100578 2.391 ENSMUST00000030841.5
ENSMUST00000163409.1
Klhl7

kelch-like 7

chr7_-_14562171 2.377 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr11_-_115627948 2.326 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
Slc25a19


solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19


chr12_+_84052114 2.301 ENSMUST00000120927.1
Acot3
acyl-CoA thioesterase 3
chr17_+_35236556 2.241 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr10_+_52358767 2.200 ENSMUST00000180473.1
Gm26741
predicted gene, 26741
chrM_+_14138 2.101 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr9_-_97111117 2.038 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr2_-_134644125 1.898 ENSMUST00000038228.4
Tmx4
thioredoxin-related transmembrane protein 4
chr3_-_89411781 1.863 ENSMUST00000107429.3
ENSMUST00000129308.2
ENSMUST00000107426.1
ENSMUST00000050398.4
ENSMUST00000162701.1
Flad1




RFad1, flavin adenine dinucleotide synthetase, homolog (yeast)




chr1_-_5070281 1.791 ENSMUST00000147158.1
ENSMUST00000118000.1
Rgs20

regulator of G-protein signaling 20

chr19_+_34217588 1.784 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr9_+_64235201 1.734 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr14_+_21481428 1.716 ENSMUST00000182996.1
Kat6b
K(lysine) acetyltransferase 6B
chr5_+_140735526 1.594 ENSMUST00000120630.2
Amz1
archaelysin family metallopeptidase 1
chr13_-_62371936 1.514 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr2_+_164948219 1.508 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr12_+_36157124 1.507 ENSMUST00000041640.3
Ankmy2
ankyrin repeat and MYND domain containing 2
chr1_+_65186727 1.500 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr7_-_141434532 1.492 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr12_-_36156781 1.454 ENSMUST00000020856.4
Bzw2
basic leucine zipper and W2 domains 2
chr3_-_62506970 1.430 ENSMUST00000029336.4
Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr12_+_10390756 1.428 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr7_+_45896941 1.411 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr8_-_4217133 1.391 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr9_+_109054839 1.368 ENSMUST00000154184.1
Shisa5
shisa homolog 5 (Xenopus laevis)
chr2_-_121473993 1.332 ENSMUST00000056732.3
Mfap1b
microfibrillar-associated protein 1B
chr8_-_4217261 1.332 ENSMUST00000168386.2
BC068157
cDNA sequence BC068157
chr8_-_4216912 1.303 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr4_-_46566432 1.253 ENSMUST00000030021.7
ENSMUST00000107757.1
Coro2a

coronin, actin binding protein 2A

chr9_-_53667429 1.237 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr10_+_58446845 1.146 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr6_+_126939957 1.091 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr3_+_89715016 1.008 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr2_-_165400398 0.968 ENSMUST00000029213.4
Ocstamp
osteoclast stimulatory transmembrane protein
chr17_+_22689771 0.935 ENSMUST00000055305.8
Gm9805
predicted gene 9805
chr19_-_6118491 0.925 ENSMUST00000113533.1
Sac3d1
SAC3 domain containing 1
chr14_-_18894255 0.909 ENSMUST00000124353.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chrM_-_14060 0.889 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr5_+_130369420 0.873 ENSMUST00000086029.3
Caln1
calneuron 1
chr9_-_113708209 0.846 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr5_-_135251209 0.791 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr10_-_111997204 0.741 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr1_-_65186456 0.728 ENSMUST00000169032.1
Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr7_+_45897429 0.616 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr16_-_36874806 0.605 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr5_+_121660528 0.508 ENSMUST00000031414.8
Brap
BRCA1 associated protein
chr4_-_19570073 0.489 ENSMUST00000029885.4
Cpne3
copine III
chr1_-_171059390 0.459 ENSMUST00000164044.1
ENSMUST00000169017.1
Fcgr3

Fc receptor, IgG, low affinity III

chr10_+_53337686 0.450 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chrM_+_7759 0.405 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_-_31739763 0.390 ENSMUST00000178878.1
Gm5117
predicted gene 5117
chr7_-_103741322 0.321 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr2_+_172248492 0.321 ENSMUST00000038532.1
Mc3r
melanocortin 3 receptor
chr9_+_13662460 0.285 ENSMUST00000177755.1
Maml2
mastermind like 2 (Drosophila)
chr5_+_29378604 0.269 ENSMUST00000181005.1
4632411P08Rik
RIKEN cDNA 4632411P08 gene
chr5_-_113310697 0.259 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr1_+_44119952 0.250 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chr12_+_69296676 0.248 ENSMUST00000021362.4
Klhdc2
kelch domain containing 2
chr4_+_42714926 0.184 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr19_+_3323301 0.160 ENSMUST00000025835.4
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr8_-_109962127 0.151 ENSMUST00000001722.7
ENSMUST00000051430.6
Marveld3

MARVEL (membrane-associating) domain containing 3

chr11_-_69695802 0.131 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr5_-_100373484 0.122 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr2_-_94010807 0.109 ENSMUST00000111240.1
Alkbh3
alkB, alkylation repair homolog 3 (E. coli)
chr9_+_76014855 0.048 ENSMUST00000008052.6
ENSMUST00000183425.1
ENSMUST00000183979.1
ENSMUST00000117981.2
Hmgcll1



3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 7.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6 1.9 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.6 2.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.4 2.1 GO:0033762 response to glucagon(GO:0033762)
0.4 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 1.0 GO:0034241 positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289)
0.3 1.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) positive regulation of receptor binding(GO:1900122)
0.3 2.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 2.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 5.6 GO:0010107 potassium ion import(GO:0010107)
0.2 0.8 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.5 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 1.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 2.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 11.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 3.9 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.1 1.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 5.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 2.0 GO:0006862 nucleotide transport(GO:0006862)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.5 GO:0032288 myelin assembly(GO:0032288)
0.1 2.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 1.4 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.5 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 1.1 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 7.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 2.6 GO:0015992 proton transport(GO:0015992)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 2.3 GO:0098792 xenophagy(GO:0098792)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 2.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.0 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 1.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 0.9 GO:0070469 respiratory chain(GO:0070469)
0.3 2.1 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 2.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 2.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.3 GO:0001527 microfibril(GO:0001527)
0.1 7.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 11.1 GO:0008021 synaptic vesicle(GO:0008021)
0.1 5.6 GO:0030315 T-tubule(GO:0030315)
0.1 2.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 7.1 GO:0043197 dendritic spine(GO:0043197)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 4.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.0 7.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.8 4.9 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.5 11.1 GO:0031489 myosin V binding(GO:0031489)
0.4 4.6 GO:0048038 quinone binding(GO:0048038)
0.3 1.0 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.3 1.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 0.8 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 2.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 5.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.8 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.2 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 2.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 2.0 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.3 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.4 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 1.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 1.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 6.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 2.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)