Motif ID: Arid3a

Z-value: 0.666


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927039_79927139-0.613.8e-07Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_24493656 8.820 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr15_+_99006056 7.830 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr12_-_4689926 7.690 ENSMUST00000080062.6
 Gm17541
predicted gene, 17541
chr5_-_70842617 4.077 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr12_+_65225513 2.809 ENSMUST00000046331.4
 Wdr20b
WD repeat domain 20b
chr2_-_176144697 2.803 ENSMUST00000178872.1
 Gm2004
predicted gene 2004
chr1_+_17145357 2.699 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr2_+_177009681 2.658 ENSMUST00000178182.1
 Gm14419
predicted gene 14419
chr15_+_100334929 2.488 ENSMUST00000075420.4
 Mettl7a3
methyltransferase like 7A3
chr11_-_110095937 2.441 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr12_-_108003414 2.358 ENSMUST00000109887.1
ENSMUST00000109891.2
 Bcl11b

B cell leukemia/lymphoma 11B

chr2_-_32982007 2.158 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chrX_+_163911401 1.763 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_116654245 1.755 ENSMUST00000021166.5
 Cygb
cytoglobin
chr1_+_179961110 1.752 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr1_-_150392719 1.745 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr4_+_141368116 1.691 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr9_+_114731177 1.682 ENSMUST00000035007.8
 Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr18_+_36939178 1.651 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr13_-_23762378 1.633 ENSMUST00000091701.2
 Hist1h3a
histone cluster 1, H3a
chr12_-_4769217 1.585 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr10_+_123264076 1.576 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr3_-_85741389 1.549 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr11_-_110095974 1.548 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr4_-_87806276 1.542 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_+_4769375 1.508 ENSMUST00000178879.1
 Pfn4
profilin family, member 4
chr3_-_116129615 1.482 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr14_+_120275669 1.421 ENSMUST00000088419.6
ENSMUST00000167459.1
 Mbnl2

muscleblind-like 2

chr1_+_179960472 1.373 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr2_-_175133322 1.325 ENSMUST00000099029.3
 Gm14399
predicted gene 14399
chr2_+_176807362 1.304 ENSMUST00000179435.1
 Gm14295
predicted gene 14295
chr18_-_6241486 1.302 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr2_+_3770673 1.248 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr17_+_3532554 1.219 ENSMUST00000168560.1
 Cldn20
claudin 20
chr10_+_69533761 1.127 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr8_-_46080284 1.037 ENSMUST00000177186.1
 Snx25
sorting nexin 25
chr4_-_87806296 1.022 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr12_-_108003594 0.969 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr9_+_108392820 0.959 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr3_+_32436376 0.936 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_+_54538984 0.920 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr11_-_80377975 0.912 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr7_+_99594605 0.911 ENSMUST00000162290.1
 Arrb1
arrestin, beta 1
chr14_+_105681824 0.843 ENSMUST00000073238.6
 Gm10076
predicted gene 10076
chr12_+_4769278 0.838 ENSMUST00000020967.4
 Pfn4
profilin family, member 4
chrX_-_134111852 0.822 ENSMUST00000033610.6
 Nox1
NADPH oxidase 1
chrX_+_153237466 0.814 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr16_+_43510267 0.797 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr9_-_42457594 0.793 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr10_+_79996479 0.724 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr3_+_32436151 0.721 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_+_60181495 0.719 ENSMUST00000160834.1
 Nbeal1
neurobeachin like 1
chr15_-_3583191 0.713 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr2_-_175327598 0.676 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr4_+_134930898 0.675 ENSMUST00000030622.2
 Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr2_+_164460945 0.639 ENSMUST00000072452.4
 Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr12_-_87444017 0.625 ENSMUST00000091090.4
 2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr8_+_95534078 0.623 ENSMUST00000041569.3
 Ccdc113
coiled-coil domain containing 113
chr18_+_35770318 0.595 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr3_+_30602056 0.576 ENSMUST00000047502.7
 Mynn
myoneurin
chr1_+_150392794 0.569 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr5_-_23616528 0.565 ENSMUST00000088392.4
 Srpk2
serine/arginine-rich protein specific kinase 2
chr10_-_100589205 0.559 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr17_-_24936894 0.546 ENSMUST00000115228.2
ENSMUST00000117509.1
ENSMUST00000121723.1
ENSMUST00000119115.1
ENSMUST00000121787.1
ENSMUST00000088345.5
ENSMUST00000120035.1
 Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr17_-_24936969 0.542 ENSMUST00000178969.1
ENSMUST00000115229.3
 Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

chr3_+_95282897 0.494 ENSMUST00000039537.7
ENSMUST00000107187.2
 Fam63a

family with sequence similarity 63, member A

chr10_-_58675631 0.448 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr1_-_158958367 0.435 ENSMUST00000159861.2
 Pappa2
pappalysin 2
chr4_-_108071327 0.434 ENSMUST00000106701.1
 Scp2
sterol carrier protein 2, liver
chr17_+_29274078 0.404 ENSMUST00000149405.2
 BC004004
cDNA sequence BC004004
chr8_-_85432841 0.391 ENSMUST00000047749.5
 4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr11_-_98018308 0.383 ENSMUST00000107561.2
 Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr7_+_27452417 0.382 ENSMUST00000108357.1
 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr6_+_51544513 0.377 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10

chr11_+_87664274 0.339 ENSMUST00000092800.5
 Rnf43
ring finger protein 43
chr16_-_57292845 0.318 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
 Tmem30c


transmembrane protein 30C


chr18_-_6241470 0.318 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr1_+_155158703 0.271 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr5_+_86804214 0.196 ENSMUST00000119339.1
ENSMUST00000120498.1
 Ythdc1

YTH domain containing 1

chr3_-_146495115 0.144 ENSMUST00000093951.2
 Spata1
spermatogenesis associated 1
chr14_+_59201418 0.129 ENSMUST00000140136.2
ENSMUST00000142326.1
 Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr4_+_139923349 0.129 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr12_+_69963452 0.038 ENSMUST00000110560.1
 Gm3086
predicted gene 3086

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.6 1.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 1.6 GO:0035617 stress granule disassembly(GO:0035617)
0.4 1.8 GO:0015671 oxygen transport(GO:0015671)
0.3 2.6 GO:0007379 segment specification(GO:0007379)
0.2 2.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.8 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.2 0.6 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 3.1 GO:0007097 nuclear migration(GO:0007097)
0.1 1.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 3.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.9 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.4 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.1 2.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.8 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.2 GO:0046323 glucose import(GO:0046323)
0.0 1.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 3.2 GO:0006869 lipid transport(GO:0006869)
0.0 0.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 4.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.5 GO:0002102 podosome(GO:0002102)
0.1 0.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004096 catalase activity(GO:0004096)
0.4 1.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 0.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 4.1 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.2 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.2 2.2 GO:0005536 glucose binding(GO:0005536)
0.1 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 2.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 1.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 4.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.5 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 3.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)