Motif ID: Arnt2

Z-value: 0.420


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.191.5e-01Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_101496648 3.427 ENSMUST00000106930.1
ENSMUST00000154120.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr2_-_54085542 2.961 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_-_5098418 2.086 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr7_-_45370559 1.297 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr7_+_130865756 1.092 ENSMUST00000120441.1
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_33371486 1.077 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr7_+_130865835 0.994 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr2_-_33371400 0.970 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr17_-_46890405 0.963 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr1_-_58973421 0.852 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr5_-_115300957 0.840 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr14_-_63543931 0.786 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr4_-_123116686 0.767 ENSMUST00000166337.1
Gm17244
predicted gene, 17244
chr1_+_59912972 0.749 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr5_-_115300912 0.723 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr1_-_16619245 0.648 ENSMUST00000182984.1
ENSMUST00000182554.1
Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr12_-_59011996 0.611 ENSMUST00000021375.5
Sec23a
SEC23A (S. cerevisiae)
chr17_-_26508463 0.603 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr1_+_58973521 0.569 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr1_+_87327008 0.552 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr8_+_83900706 0.536 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1


latrophilin 1


chr13_+_118714678 0.524 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr1_+_87327044 0.514 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr1_-_52817503 0.501 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr1_-_52817643 0.495 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chrX_+_99136119 0.486 ENSMUST00000052839.6
Efnb1
ephrin B1
chr2_+_79255500 0.463 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr17_+_46890621 0.461 ENSMUST00000040434.7
Tbcc
tubulin-specific chaperone C
chr7_-_44869788 0.442 ENSMUST00000046575.9
Ptov1
prostate tumor over expressed gene 1
chr11_+_107547925 0.406 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr18_+_31634374 0.380 ENSMUST00000025109.7
Sap130
Sin3A associated protein
chr4_-_41275091 0.324 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr18_+_31634368 0.323 ENSMUST00000178164.1
Sap130
Sin3A associated protein
chr1_+_87326997 0.270 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr10_-_63421739 0.242 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr5_-_135251209 0.229 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr3_+_69721985 0.222 ENSMUST00000029358.8
Nmd3
NMD3 homolog (S. cerevisiae)
chr6_+_4601124 0.207 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr13_+_13590402 0.167 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr4_+_148041172 0.131 ENSMUST00000069604.8
Mthfr
5,10-methylenetetrahydrofolate reductase
chr2_+_119208975 0.129 ENSMUST00000102519.4
Zfyve19
zinc finger, FYVE domain containing 19
chr7_+_19076242 0.048 ENSMUST00000032570.7
ENSMUST00000108479.1
Dmwd

dystrophia myotonica-containing WD repeat motif

chr11_+_43528759 0.034 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr2_+_5951440 0.016 ENSMUST00000060092.6
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 2.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 2.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 0.5 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 2.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:1904996 diapedesis(GO:0050904) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.2 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.1 1.0 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.6 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 3.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 1.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)