Motif ID: Atf1_Creb5

Z-value: 0.690

Transcription factors associated with Atf1_Creb5:

Gene SymbolEntrez IDGene Name
Atf1 ENSMUSG00000023027.6 Atf1
Creb5 ENSMUSG00000053007.6 Creb5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf1mm10_v2_chr15_+_100227871_100227878-0.246.7e-02Click!
Creb5mm10_v2_chr6_+_53573364_53573394-0.133.2e-01Click!


Activity profile for motif Atf1_Creb5.

activity profile for motif Atf1_Creb5


Sorted Z-values histogram for motif Atf1_Creb5

Sorted Z-values for motif Atf1_Creb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf1_Creb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_23761223 5.259 ENSMUST00000102964.2
 Hist1h4a
histone cluster 1, H4a
chr10_+_29211637 4.656 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr2_+_155276297 4.593 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr6_-_55681257 4.487 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr19_-_61228396 4.448 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr9_-_96752822 4.357 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr5_-_124032214 3.698 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr12_+_79130777 3.586 ENSMUST00000021550.6
 Arg2
arginase type II
chr7_-_126949499 3.565 ENSMUST00000106339.1
ENSMUST00000052937.5
 Asphd1

aspartate beta-hydroxylase domain containing 1

chr12_+_102554966 3.500 ENSMUST00000021610.5
 Chga
chromogranin A
chrX_+_170009659 3.373 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr11_+_101468164 3.241 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr9_-_98032983 2.900 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr11_+_113619318 2.879 ENSMUST00000146390.2
ENSMUST00000106630.1
 Sstr2

somatostatin receptor 2

chrX_-_21061981 2.834 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
 Zfp182


zinc finger protein 182


chr15_-_84105662 2.823 ENSMUST00000082365.5
 Sult4a1
sulfotransferase family 4A, member 1
chr13_-_22042949 2.782 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr10_-_102490418 2.760 ENSMUST00000020040.3
 Nts
neurotensin
chr9_+_53850243 2.730 ENSMUST00000048485.5
 Sln
sarcolipin
chr6_+_54681687 2.690 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 164 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 5.3 GO:0016579 protein deubiquitination(GO:0016579)
0.5 5.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 4.6 GO:0021542 dentate gyrus development(GO:0021542)
0.2 4.5 GO:0001553 luteinization(GO:0001553)
0.4 4.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.5 4.3 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.2 3.7 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 3.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
1.2 3.6 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
1.2 3.5 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.2 3.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 3.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 3.0 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.3 2.9 GO:0030432 peristalsis(GO:0030432)
0.0 2.8 GO:0006342 chromatin silencing(GO:0006342)
0.7 2.7 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 2.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.5 2.3 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.4 2.2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.8 GO:0000786 nucleosome(GO:0000786)
0.3 5.3 GO:0000421 autophagosome membrane(GO:0000421)
0.3 5.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 4.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 3.5 GO:0042583 chromaffin granule(GO:0042583)
0.3 3.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 3.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.7 GO:0035253 ciliary rootlet(GO:0035253)
0.3 2.5 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 2.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.2 GO:0072562 blood microparticle(GO:0072562)
0.0 2.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 2.0 GO:0016589 NURF complex(GO:0016589)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0042393 histone binding(GO:0042393)
0.3 6.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 5.3 GO:0005125 cytokine activity(GO:0005125)
0.1 5.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 4.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 4.6 GO:0015631 tubulin binding(GO:0015631)
0.2 4.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.6 4.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5 4.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 4.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 3.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.6 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.4 3.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 3.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.0 2.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 2.3 GO:0042169 SH2 domain binding(GO:0042169)