Motif ID: Atf5
Z-value: 1.000
Transcription factors associated with Atf5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf5 | ENSMUSG00000038539.8 | Atf5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf5 | mm10_v2_chr7_-_44816586_44816658 | 0.57 | 2.8e-06 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 8.6 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
1.8 | 5.5 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
1.6 | 4.7 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
1.5 | 5.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
1.3 | 3.9 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
1.3 | 9.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
1.3 | 5.2 | GO:1990743 | protein sialylation(GO:1990743) |
1.2 | 3.5 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
1.0 | 4.9 | GO:0034436 | glycoprotein transport(GO:0034436) |
0.8 | 3.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.8 | 6.0 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.7 | 11.8 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.7 | 2.1 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
0.7 | 2.0 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.6 | 1.8 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166) |
0.6 | 0.6 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.6 | 1.7 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.5 | 5.3 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.5 | 1.9 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.4 | 1.3 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.4 | 2.3 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.4 | 17.0 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.4 | 2.1 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
0.3 | 6.1 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.3 | 3.0 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.3 | 2.9 | GO:0030035 | microspike assembly(GO:0030035) |
0.3 | 3.2 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.3 | 0.9 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.3 | 3.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.3 | 2.0 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.3 | 1.4 | GO:0042701 | progesterone secretion(GO:0042701) |
0.3 | 7.2 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.3 | 8.3 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.3 | 3.7 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
0.3 | 2.8 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
0.2 | 3.7 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 2.9 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.2 | 7.0 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.2 | 5.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 0.9 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
0.2 | 8.3 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.2 | 1.5 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
0.2 | 3.0 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.2 | 0.8 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.2 | 2.5 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598) |
0.1 | 2.1 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
0.1 | 0.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.1 | 4.7 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.1 | 0.8 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
0.1 | 3.7 | GO:0003170 | heart valve development(GO:0003170) |
0.1 | 4.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 7.9 | GO:0060976 | coronary vasculature development(GO:0060976) |
0.1 | 1.2 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.1 | 0.3 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.1 | 0.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 1.1 | GO:0051205 | ionotropic glutamate receptor signaling pathway(GO:0035235) protein insertion into membrane(GO:0051205) |
0.1 | 0.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 2.0 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.3 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.0 | 2.2 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
0.0 | 5.2 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.0 | 2.1 | GO:0030705 | cytoskeleton-dependent intracellular transport(GO:0030705) |
0.0 | 1.1 | GO:0030641 | regulation of cellular pH(GO:0030641) |
0.0 | 2.8 | GO:0006906 | vesicle fusion(GO:0006906) |
0.0 | 3.1 | GO:0072659 | protein localization to plasma membrane(GO:0072659) |
0.0 | 0.1 | GO:0021854 | hypothalamus development(GO:0021854) |
0.0 | 0.7 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 17.0 | GO:0043083 | synaptic cleft(GO:0043083) |
1.2 | 6.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.7 | 5.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.5 | 5.5 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.5 | 2.8 | GO:0044308 | axonal spine(GO:0044308) |
0.4 | 8.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.4 | 1.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.4 | 4.9 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.3 | 3.0 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.3 | 2.1 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
0.2 | 2.1 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 11.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.2 | 2.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.2 | 14.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.2 | 2.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.2 | 3.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.2 | 2.2 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 6.5 | GO:0044295 | axonal growth cone(GO:0044295) |
0.1 | 6.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.1 | 4.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 3.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.1 | 0.9 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 1.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 1.2 | GO:0033270 | paranode region of axon(GO:0033270) |
0.1 | 0.7 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.0 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.9 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 3.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 4.9 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 3.2 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 11.5 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 2.9 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.6 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 1.9 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.0 | 1.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 1.3 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 9.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 1.8 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 2.2 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 17.0 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
1.6 | 4.9 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
1.6 | 4.7 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
1.0 | 6.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.9 | 5.2 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.8 | 3.2 | GO:0071532 | ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532) |
0.8 | 2.3 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.6 | 11.8 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.5 | 8.9 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.4 | 1.3 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.4 | 4.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.4 | 3.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.3 | 2.0 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.3 | 1.7 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.2 | 8.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.2 | 8.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.2 | 3.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.2 | 8.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.2 | 5.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.2 | 2.7 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.1 | 2.8 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 2.6 | GO:0008143 | poly(A) binding(GO:0008143) |
0.1 | 5.0 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.1 | 1.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.1 | 2.1 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.1 | 7.0 | GO:0005262 | calcium channel activity(GO:0005262) |
0.1 | 0.9 | GO:0001846 | opsonin binding(GO:0001846) |
0.1 | 2.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.1 | 3.1 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 0.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.1 | 7.1 | GO:0005125 | cytokine activity(GO:0005125) |
0.1 | 3.0 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.1 | 4.1 | GO:0030276 | clathrin binding(GO:0030276) |
0.1 | 3.5 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
0.1 | 2.8 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
0.1 | 7.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.1 | 3.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.4 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821) |
0.0 | 0.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 2.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 1.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 5.1 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.9 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 2.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.8 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |