Motif ID: Atf6

Z-value: 1.204


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.095.1e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_23988852 10.945 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr3_+_123267445 9.162 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr8_-_70487314 9.130 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr5_+_134986191 8.649 ENSMUST00000094245.2
Cldn3
claudin 3
chr7_+_126950518 8.503 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr7_+_126950687 7.818 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr12_+_82616885 7.652 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr7_+_126950837 7.629 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr5_-_136170634 7.626 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr18_-_31447383 7.000 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr10_+_29211637 6.923 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr8_-_70700070 6.792 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr6_-_136173492 6.355 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr6_+_77242644 5.795 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 5.762 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr11_+_69991061 5.177 ENSMUST00000018711.8
Gabarap
gamma-aminobutyric acid receptor associated protein
chr2_+_155276297 4.948 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr6_-_124464772 4.839 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr17_+_46297917 4.823 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr4_+_43406435 4.550 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 24.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.6 14.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
3.6 10.9 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.7 10.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.9 10.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 9.8 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
1.1 8.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7 8.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.5 8.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.9 8.1 GO:0090166 Golgi disassembly(GO:0090166)
0.3 8.1 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.5 7.1 GO:0045176 apical protein localization(GO:0045176)
0.9 7.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 6.7 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 5.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
1.9 5.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 5.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.9 5.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.7 5.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 5.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 31.5 GO:0043025 neuronal cell body(GO:0043025)
0.1 19.2 GO:0030426 growth cone(GO:0030426)
0.4 17.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 10.1 GO:0000421 autophagosome membrane(GO:0000421)
0.9 10.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 10.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 9.3 GO:0005657 replication fork(GO:0005657)
0.4 8.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 8.6 GO:0043034 costamere(GO:0043034)
0.2 8.1 GO:0031201 SNARE complex(GO:0031201)
0.1 7.6 GO:0097060 synaptic membrane(GO:0097060)
0.2 7.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 7.4 GO:0043209 myelin sheath(GO:0043209)
0.1 5.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 5.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 5.3 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.7 4.9 GO:0005827 polar microtubule(GO:0005827)
0.1 4.9 GO:0043197 dendritic spine(GO:0043197)
0.3 4.7 GO:0031045 dense core granule(GO:0031045)
0.1 4.4 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.9 10.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 8.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 8.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.5 8.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.7 8.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 6.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 6.7 GO:0005096 GTPase activator activity(GO:0005096)
0.6 6.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 6.2 GO:0005158 insulin receptor binding(GO:0005158)
1.4 5.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 5.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.8 5.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.7 5.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 5.2 GO:0050811 GABA receptor binding(GO:0050811)
0.2 5.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 4.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.9 4.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.9 4.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)