Motif ID: Atf7_E4f1

Z-value: 1.196

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf7mm10_v2_chr15_-_102529025_102529025-0.572.1e-06Click!
E4f1mm10_v2_chr17_-_24455265_24455345-0.522.0e-05Click!


Activity profile for motif Atf7_E4f1.

activity profile for motif Atf7_E4f1


Sorted Z-values histogram for motif Atf7_E4f1

Sorted Z-values for motif Atf7_E4f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 12.632 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_67374116 12.300 ENSMUST00000061322.8
 Mlf1
myeloid leukemia factor 1
chr3_+_67374091 11.079 ENSMUST00000077916.5
 Mlf1
myeloid leukemia factor 1
chr9_-_20976762 10.973 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr4_+_141301228 9.737 ENSMUST00000006614.2
 Epha2
Eph receptor A2
chr4_+_111720187 9.503 ENSMUST00000084354.3
 Spata6
spermatogenesis associated 6
chr8_+_116921735 9.221 ENSMUST00000034205.4
 Cenpn
centromere protein N
chr5_-_106458440 9.210 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr7_-_144939823 9.047 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr3_-_36571952 8.553 ENSMUST00000029270.3
 Ccna2
cyclin A2
chr17_-_71526819 7.289 ENSMUST00000024851.9
 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_40800054 6.909 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr3_+_135212557 6.514 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr17_+_36958623 6.252 ENSMUST00000173814.1
 Znrd1as
Znrd1 antisense
chr8_+_92674289 6.020 ENSMUST00000034185.6
 Irx6
Iroquois related homeobox 6 (Drosophila)
chr13_+_8885501 5.935 ENSMUST00000169314.2
 Idi1
isopentenyl-diphosphate delta isomerase
chr1_+_74791516 5.878 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr19_+_59260878 5.844 ENSMUST00000026084.3
 Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr17_-_31277327 5.754 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr13_+_8885937 5.665 ENSMUST00000177397.1
ENSMUST00000177400.1
ENSMUST00000177447.1
 Idi1


isopentenyl-diphosphate delta isomerase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 222 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 18.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 14.6 GO:0006412 translation(GO:0006412)
0.1 13.9 GO:0042254 ribosome biogenesis(GO:0042254)
2.8 13.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.5 13.7 GO:0034508 centromere complex assembly(GO:0034508)
1.9 13.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
2.1 12.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 12.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.5 11.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
3.7 11.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.8 11.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 10.4 GO:0048864 stem cell development(GO:0048864)
2.5 10.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.8 10.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
3.2 9.7 GO:0014028 notochord formation(GO:0014028)
0.8 9.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.9 9.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.8 9.5 GO:0044458 motile cilium assembly(GO:0044458)
1.9 9.3 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.3 9.2 GO:0001709 cell fate determination(GO:0001709)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 37.0 GO:0031514 motile cilium(GO:0031514)
0.1 27.2 GO:0005667 transcription factor complex(GO:0005667)
0.2 25.1 GO:0000776 kinetochore(GO:0000776)
0.1 21.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 19.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 13.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 12.0 GO:0005730 nucleolus(GO:0005730)
0.2 11.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.3 11.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 11.1 GO:0031965 nuclear membrane(GO:0031965)
3.5 10.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.6 9.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.2 9.6 GO:0098536 deuterosome(GO:0098536)
0.0 9.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 9.2 GO:0005844 polysome(GO:0005844)
0.2 9.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.0 8.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.2 8.6 GO:0001940 male pronucleus(GO:0001940)
0.9 8.6 GO:0005642 annulate lamellae(GO:0005642)
0.4 8.1 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 24.5 GO:0044822 poly(A) RNA binding(GO:0044822)
0.1 20.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 19.4 GO:0003677 DNA binding(GO:0003677)
0.1 18.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.9 13.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 11.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 11.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.5 10.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 10.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 10.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 9.7 GO:0017160 Ral GTPase binding(GO:0017160)
1.9 9.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 9.5 GO:0005198 structural molecule activity(GO:0005198)
0.8 9.3 GO:0003680 AT DNA binding(GO:0003680)
0.4 9.2 GO:0008266 poly(U) RNA binding(GO:0008266)
1.5 9.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.4 9.0 GO:0070064 proline-rich region binding(GO:0070064)
0.7 8.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 7.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 7.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)