Motif ID: Atf7_E4f1
Z-value: 1.196
Transcription factors associated with Atf7_E4f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf7 | ENSMUSG00000052414.9 | Atf7 |
Atf7 | ENSMUSG00000071584.1 | Atf7 |
E4f1 | ENSMUSG00000024137.8 | E4f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf7 | mm10_v2_chr15_-_102529025_102529025 | -0.57 | 2.1e-06 | Click! |
E4f1 | mm10_v2_chr17_-_24455265_24455345 | -0.52 | 2.0e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.7 | 11.0 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
3.2 | 9.7 | GO:0014028 | notochord formation(GO:0014028) |
2.8 | 13.8 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
2.5 | 10.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
2.3 | 9.1 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
2.2 | 8.8 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
2.1 | 12.6 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
2.1 | 18.9 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
1.9 | 13.5 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
1.9 | 9.6 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
1.9 | 9.3 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) |
1.8 | 11.0 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
1.6 | 1.6 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
1.6 | 4.7 | GO:0060067 | cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
1.4 | 8.6 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
1.3 | 9.0 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
1.2 | 3.6 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) |
1.1 | 4.5 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
1.0 | 2.0 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
1.0 | 5.8 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
1.0 | 2.9 | GO:0035973 | aggrephagy(GO:0035973) |
0.9 | 8.3 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.9 | 3.7 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
0.9 | 4.6 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.9 | 2.7 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.9 | 2.6 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.9 | 2.6 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.8 | 10.0 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.8 | 9.7 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.8 | 9.5 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.8 | 3.1 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.8 | 8.5 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.8 | 2.3 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.7 | 3.6 | GO:0031052 | programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) |
0.7 | 5.0 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.7 | 2.0 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.7 | 6.0 | GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030) |
0.7 | 4.6 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.7 | 5.9 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.6 | 1.9 | GO:0030167 | proteoglycan catabolic process(GO:0030167) |
0.6 | 3.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.6 | 3.1 | GO:0060051 | negative regulation of protein glycosylation(GO:0060051) |
0.6 | 1.8 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.6 | 3.1 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.6 | 3.4 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.5 | 1.5 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
0.5 | 11.7 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
0.5 | 1.4 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.5 | 13.7 | GO:0034508 | centromere complex assembly(GO:0034508) |
0.4 | 1.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) |
0.4 | 2.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.4 | 1.7 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.4 | 4.3 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.4 | 2.5 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
0.4 | 2.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.4 | 2.9 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
0.4 | 2.0 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.4 | 1.5 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.4 | 1.1 | GO:0051030 | snRNA transport(GO:0051030) |
0.4 | 1.1 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.3 | 3.0 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.3 | 2.0 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.3 | 1.0 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.3 | 2.2 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.3 | 2.5 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.3 | 0.9 | GO:0048597 | post-embryonic camera-type eye morphogenesis(GO:0048597) |
0.3 | 1.8 | GO:0023014 | MAPK cascade(GO:0000165) signal transduction by protein phosphorylation(GO:0023014) |
0.3 | 3.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.3 | 2.3 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.3 | 1.2 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
0.3 | 3.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.3 | 1.2 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.3 | 1.1 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.3 | 5.1 | GO:0007530 | sex determination(GO:0007530) |
0.3 | 2.0 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.3 | 1.1 | GO:0048539 | bone marrow development(GO:0048539) |
0.3 | 2.5 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
0.3 | 7.9 | GO:0009409 | response to cold(GO:0009409) |
0.3 | 1.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.3 | 1.6 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.3 | 2.9 | GO:0019985 | translesion synthesis(GO:0019985) |
0.3 | 3.1 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.3 | 9.2 | GO:0001709 | cell fate determination(GO:0001709) |
0.2 | 1.0 | GO:0006407 | rRNA export from nucleus(GO:0006407) |
0.2 | 0.7 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.2 | 4.0 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.2 | 0.7 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.2 | 0.9 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
0.2 | 1.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.2 | 0.9 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
0.2 | 4.0 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
0.2 | 0.7 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.2 | 2.2 | GO:0010225 | response to UV-C(GO:0010225) |
0.2 | 0.9 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
0.2 | 1.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.2 | 0.7 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.2 | 1.1 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.2 | 2.5 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.2 | 3.3 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.2 | 2.1 | GO:1990403 | embryonic brain development(GO:1990403) |
0.2 | 0.8 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.2 | 3.2 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.2 | 1.8 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.2 | 7.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.2 | 2.9 | GO:0021542 | dentate gyrus development(GO:0021542) |
0.2 | 3.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.2 | 7.8 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.2 | 1.2 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.2 | 3.8 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.2 | 2.6 | GO:0042407 | cristae formation(GO:0042407) |
0.2 | 1.1 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
0.2 | 2.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.2 | 3.0 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.2 | 1.0 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.2 | 0.7 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.2 | 0.3 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
0.2 | 3.3 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.2 | 4.1 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.2 | 0.8 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.2 | 1.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.2 | 5.8 | GO:0035082 | axoneme assembly(GO:0035082) |
0.2 | 0.5 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.2 | 3.9 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.2 | 0.8 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.2 | 2.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.2 | 0.6 | GO:0046836 | glycolipid transport(GO:0046836) |
0.1 | 0.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.1 | 0.6 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.1 | 2.7 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 12.1 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
0.1 | 1.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 1.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.4 | GO:2000832 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.1 | 1.7 | GO:0030261 | chromosome condensation(GO:0030261) |
0.1 | 0.7 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
0.1 | 2.0 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
0.1 | 1.9 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.1 | 0.7 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.1 | 8.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.1 | 0.8 | GO:0051036 | regulation of endosome size(GO:0051036) |
0.1 | 1.0 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.1 | 0.4 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
0.1 | 0.6 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.1 | 0.7 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
0.1 | 1.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 1.4 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
0.1 | 0.5 | GO:0060021 | palate development(GO:0060021) |
0.1 | 1.0 | GO:0051923 | sulfation(GO:0051923) |
0.1 | 2.7 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
0.1 | 0.3 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 0.8 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.1 | 2.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.3 | GO:0030070 | insulin processing(GO:0030070) |
0.1 | 0.2 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
0.1 | 1.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.1 | 0.2 | GO:0009644 | response to high light intensity(GO:0009644) |
0.1 | 3.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.1 | 0.5 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.1 | 0.8 | GO:0000054 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428) |
0.1 | 1.2 | GO:0060972 | left/right pattern formation(GO:0060972) |
0.1 | 1.4 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.1 | 0.3 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
0.1 | 0.9 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.7 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.1 | 1.4 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.1 | 1.1 | GO:1904872 | RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
0.1 | 0.3 | GO:1904995 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
0.1 | 0.8 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.1 | 0.7 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 1.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
0.1 | 13.9 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.1 | 3.6 | GO:0006094 | gluconeogenesis(GO:0006094) |
0.1 | 2.6 | GO:0034605 | cellular response to heat(GO:0034605) |
0.1 | 0.6 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.1 | 0.6 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.1 | 1.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.1 | 10.4 | GO:0048864 | stem cell development(GO:0048864) |
0.1 | 0.3 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
0.1 | 1.2 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
0.1 | 2.7 | GO:0006352 | DNA-templated transcription, initiation(GO:0006352) |
0.1 | 3.5 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 0.2 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
0.0 | 0.9 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 0.5 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 2.2 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 3.0 | GO:1900046 | regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046) |
0.0 | 1.1 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.7 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.0 | 1.0 | GO:0031018 | endocrine pancreas development(GO:0031018) |
0.0 | 0.7 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
0.0 | 0.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.8 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.0 | 1.0 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 4.5 | GO:0098780 | mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
0.0 | 2.0 | GO:0034620 | cellular response to unfolded protein(GO:0034620) |
0.0 | 1.5 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
0.0 | 0.5 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.2 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
0.0 | 0.7 | GO:0045666 | positive regulation of neuron differentiation(GO:0045666) |
0.0 | 1.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.1 | GO:0009446 | putrescine metabolic process(GO:0009445) putrescine biosynthetic process(GO:0009446) |
0.0 | 0.9 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 14.6 | GO:0006412 | translation(GO:0006412) |
0.0 | 1.2 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 1.4 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.7 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
0.0 | 1.2 | GO:0042633 | molting cycle(GO:0042303) hair cycle(GO:0042633) |
0.0 | 0.0 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
0.0 | 0.4 | GO:0030318 | melanocyte differentiation(GO:0030318) |
0.0 | 0.5 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
0.0 | 1.6 | GO:0045333 | cellular respiration(GO:0045333) |
0.0 | 5.6 | GO:0008380 | RNA splicing(GO:0008380) |
0.0 | 3.2 | GO:0007059 | chromosome segregation(GO:0007059) |
0.0 | 1.7 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.0 | 0.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 2.1 | GO:0030336 | negative regulation of cell migration(GO:0030336) |
0.0 | 0.4 | GO:0017145 | stem cell division(GO:0017145) |
0.0 | 0.8 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.4 | GO:0051591 | response to cAMP(GO:0051591) |
0.0 | 0.9 | GO:1902652 | cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652) |
0.0 | 0.7 | GO:0030518 | intracellular steroid hormone receptor signaling pathway(GO:0030518) |
0.0 | 0.5 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 10.4 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
1.8 | 7.3 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
1.6 | 9.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
1.3 | 11.5 | GO:0030008 | TRAPP complex(GO:0030008) |
1.2 | 8.6 | GO:0001940 | male pronucleus(GO:0001940) |
1.2 | 3.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
1.2 | 9.6 | GO:0098536 | deuterosome(GO:0098536) |
1.2 | 3.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
1.0 | 3.1 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
1.0 | 8.7 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
1.0 | 2.9 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.9 | 8.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.8 | 13.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.8 | 2.4 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.8 | 4.6 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.8 | 4.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.7 | 5.8 | GO:0001520 | outer dense fiber(GO:0001520) |
0.6 | 4.5 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.6 | 3.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.6 | 4.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.5 | 3.8 | GO:0000796 | condensin complex(GO:0000796) |
0.5 | 3.7 | GO:0070187 | telosome(GO:0070187) |
0.5 | 6.0 | GO:0016589 | NURF complex(GO:0016589) |
0.5 | 3.9 | GO:0070652 | HAUS complex(GO:0070652) |
0.5 | 1.4 | GO:0097447 | dendritic tree(GO:0097447) |
0.5 | 2.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.4 | 2.9 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.4 | 8.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.4 | 19.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.3 | 4.8 | GO:0031045 | dense core granule(GO:0031045) |
0.3 | 6.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.3 | 0.9 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.3 | 37.0 | GO:0031514 | motile cilium(GO:0031514) |
0.3 | 2.6 | GO:0061617 | MICOS complex(GO:0061617) |
0.3 | 2.3 | GO:0089701 | U2AF(GO:0089701) |
0.3 | 2.8 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.3 | 1.1 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.3 | 4.3 | GO:0005652 | nuclear lamina(GO:0005652) |
0.3 | 1.1 | GO:0005745 | m-AAA complex(GO:0005745) |
0.3 | 1.8 | GO:0016461 | unconventional myosin complex(GO:0016461) |
0.2 | 2.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.2 | 1.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476) |
0.2 | 3.2 | GO:0031011 | Ino80 complex(GO:0031011) |
0.2 | 0.8 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.2 | 9.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.2 | 2.1 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.2 | 25.1 | GO:0000776 | kinetochore(GO:0000776) |
0.2 | 4.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.2 | 1.6 | GO:0045252 | dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
0.2 | 1.8 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.2 | 9.2 | GO:0005844 | polysome(GO:0005844) |
0.2 | 11.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 3.6 | GO:0002102 | podosome(GO:0002102) |
0.1 | 1.0 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.1 | 1.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 1.5 | GO:0031512 | motile primary cilium(GO:0031512) |
0.1 | 5.8 | GO:0015934 | large ribosomal subunit(GO:0015934) |
0.1 | 1.9 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 2.0 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 1.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.1 | 0.5 | GO:1990246 | uniplex complex(GO:1990246) |
0.1 | 0.8 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 21.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 3.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 1.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 1.0 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 0.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.1 | 1.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.1 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 0.4 | GO:0042827 | platelet dense granule(GO:0042827) |
0.1 | 1.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 1.4 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
0.1 | 3.3 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 1.6 | GO:0030914 | STAGA complex(GO:0030914) |
0.1 | 0.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 5.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 0.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 0.8 | GO:0044292 | dendrite terminus(GO:0044292) |
0.1 | 0.8 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.1 | 27.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 3.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 0.4 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.1 | 0.3 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 11.1 | GO:0031965 | nuclear membrane(GO:0031965) |
0.1 | 4.0 | GO:0044815 | nucleosome(GO:0000786) DNA packaging complex(GO:0044815) |
0.1 | 1.9 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.1 | 0.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 3.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 1.1 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.4 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 1.5 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.6 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.5 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 9.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 2.4 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 1.0 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.6 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 1.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.5 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 12.0 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 0.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.0 | 2.5 | GO:0031256 | leading edge membrane(GO:0031256) |
0.0 | 0.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 2.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.7 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 4.4 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
0.0 | 0.8 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.7 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.7 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.0 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.8 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
1.9 | 9.5 | GO:0032027 | myosin light chain binding(GO:0032027) |
1.6 | 6.5 | GO:0043515 | kinetochore binding(GO:0043515) |
1.5 | 9.1 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
1.5 | 10.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
1.2 | 3.7 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139) |
1.2 | 4.6 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
1.1 | 4.3 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
1.0 | 3.1 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
1.0 | 2.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.9 | 3.8 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.9 | 2.8 | GO:0043912 | D-lysine oxidase activity(GO:0043912) |
0.9 | 13.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.9 | 7.0 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.9 | 2.6 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.9 | 2.6 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.8 | 9.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.8 | 11.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.8 | 2.4 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.7 | 5.4 | GO:0001618 | virus receptor activity(GO:0001618) |
0.7 | 2.0 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.7 | 8.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.6 | 1.9 | GO:0070052 | collagen V binding(GO:0070052) |
0.6 | 3.1 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.6 | 3.6 | GO:0045340 | mercury ion binding(GO:0045340) |
0.6 | 2.4 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.5 | 1.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.5 | 1.5 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
0.5 | 1.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.5 | 7.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.5 | 4.5 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
0.4 | 9.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.4 | 9.2 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.4 | 2.5 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.4 | 4.0 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
0.4 | 3.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.4 | 9.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.4 | 1.5 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
0.4 | 6.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.4 | 4.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.3 | 5.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.3 | 3.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.3 | 1.2 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
0.3 | 0.9 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.3 | 0.9 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.3 | 1.2 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.3 | 5.4 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.3 | 2.5 | GO:0032564 | dATP binding(GO:0032564) |
0.3 | 3.3 | GO:0031996 | thioesterase binding(GO:0031996) |
0.3 | 2.2 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
0.3 | 10.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.2 | 1.9 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.2 | 0.9 | GO:0043426 | MRF binding(GO:0043426) |
0.2 | 4.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.2 | 2.3 | GO:0050733 | RS domain binding(GO:0050733) |
0.2 | 0.6 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.2 | 6.2 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.2 | 3.0 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.2 | 1.4 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
0.2 | 1.5 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
0.2 | 10.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.2 | 2.6 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.2 | 1.0 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.2 | 7.9 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
0.2 | 0.9 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.2 | 0.8 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.2 | 4.9 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 4.4 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.1 | 0.8 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 1.3 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.1 | 0.9 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 1.4 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.6 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) succinate-CoA ligase activity(GO:0004774) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) CoA-ligase activity(GO:0016405) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
0.1 | 1.1 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 1.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 2.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.9 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.1 | 6.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.1 | 1.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 0.8 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.1 | 0.3 | GO:0030519 | snoRNP binding(GO:0030519) |
0.1 | 1.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.1 | 1.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 2.6 | GO:0030515 | snoRNA binding(GO:0030515) |
0.1 | 2.3 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.1 | 0.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 1.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 20.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.1 | 1.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.1 | 18.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.1 | 1.4 | GO:0048156 | tau protein binding(GO:0048156) |
0.1 | 7.9 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
0.1 | 1.1 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.1 | 1.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 2.0 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 2.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.1 | 4.9 | GO:0031491 | nucleosome binding(GO:0031491) |
0.1 | 0.7 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.8 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 1.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 1.1 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.1 | 1.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 2.5 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.1 | 0.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.1 | 0.4 | GO:0000339 | RNA cap binding(GO:0000339) |
0.1 | 5.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 2.3 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 3.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 1.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 4.4 | GO:0020037 | heme binding(GO:0020037) |
0.1 | 2.5 | GO:0001047 | core promoter binding(GO:0001047) |
0.1 | 1.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 1.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 2.9 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.1 | 0.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 1.6 | GO:0019843 | rRNA binding(GO:0019843) |
0.1 | 0.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.1 | 4.3 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.1 | 1.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 2.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 1.3 | GO:0008607 | RNA polymerase II core binding(GO:0000993) phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.4 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 1.8 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.1 | 0.7 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.1 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 11.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.1 | 0.4 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.2 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
0.0 | 1.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 1.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.3 | GO:0045703 | pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703) |
0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 2.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 9.5 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 0.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 2.6 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 1.7 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 1.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.9 | GO:0051087 | chaperone binding(GO:0051087) |
0.0 | 24.5 | GO:0044822 | poly(A) RNA binding(GO:0044822) |
0.0 | 0.6 | GO:0016773 | phosphotransferase activity, alcohol group as acceptor(GO:0016773) |
0.0 | 0.7 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 0.1 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
0.0 | 19.4 | GO:0003677 | DNA binding(GO:0003677) |
0.0 | 0.6 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.2 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |