Motif ID: Bcl6b

Z-value: 0.545


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.522.1e-05Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 9.297 ENSMUST00000107377.3
Tnc
tenascin C
chr16_-_74411292 5.509 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 4.599 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr9_+_40269430 3.576 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr3_+_55242526 3.284 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr19_-_5797410 3.281 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chrX_+_151344171 2.966 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr8_+_13907748 2.871 ENSMUST00000043520.3
Fbxo25
F-box protein 25
chr1_-_173942445 2.816 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr13_-_98815408 2.767 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr10_-_95417099 2.374 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr2_+_119594288 2.304 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr10_+_57794335 2.285 ENSMUST00000151623.1
ENSMUST00000020022.7
Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr2_-_65567465 2.159 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_-_96240317 2.147 ENSMUST00000078756.5
Hist2h2aa2
histone cluster 2, H2aa2
chr9_-_112232449 2.122 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_-_65567505 2.013 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_-_95416850 1.882 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr10_+_81633694 1.869 ENSMUST00000140345.1
ENSMUST00000126323.1
Ankrd24

ankyrin repeat domain 24

chr6_+_149309391 1.738 ENSMUST00000130664.1
ENSMUST00000046689.6
2810474O19Rik

RIKEN cDNA 2810474O19 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 10.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
2.3 9.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 4.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.8 4.2 GO:0046684 response to pyrethroid(GO:0046684)
0.5 3.7 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 3.6 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.8 3.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 3.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
1.0 2.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 2.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.3 2.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 2.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 2.1 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 1.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 1.4 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.2 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.1 GO:0030673 axolemma(GO:0030673)
0.6 9.3 GO:0005614 interstitial matrix(GO:0005614)
0.5 7.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 4.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0005903 brush border(GO:0005903)
0.0 1.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.2 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.1 GO:0008046 axon guidance receptor activity(GO:0008046)
1.5 9.3 GO:0045545 syndecan binding(GO:0045545)
0.9 4.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 4.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 3.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 3.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 2.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.9 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 2.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.4 GO:0015265 urea channel activity(GO:0015265)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)