Motif ID: Bcl6b
Z-value: 0.545
Transcription factors associated with Bcl6b:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl6b | ENSMUSG00000000317.5 | Bcl6b |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bcl6b | mm10_v2_chr11_-_70229677_70229761 | 0.52 | 2.1e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 2.3 | 9.3 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.0 | 2.9 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.8 | 4.2 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.8 | 3.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.5 | 3.6 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.5 | 3.7 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.3 | 2.3 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 1.1 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.2 | 1.5 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.2 | 4.3 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.2 | 1.4 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
| 0.1 | 2.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.3 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.1 | 0.4 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.1 | 2.8 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.1 | 0.8 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 3.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.1 | 0.7 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.1 | 0.2 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 1.7 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 2.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 0.2 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
| 0.0 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.0 | 0.1 | GO:0042126 | nitrate metabolic process(GO:0042126) |
| 0.0 | 2.1 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.3 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 9.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.5 | 7.7 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.3 | 10.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 1.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.3 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 0.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 2.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.8 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 3.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 2.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 1.4 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 4.8 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 1.5 | GO:0005903 | brush border(GO:0005903) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 9.3 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.3 | 10.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.9 | 4.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.5 | 3.6 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.3 | 2.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.3 | 4.2 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.2 | 1.4 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.1 | 2.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.7 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 2.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 0.8 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 0.2 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.1 | 0.3 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.1 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.0 | 0.8 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 3.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 2.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 2.9 | GO:0005516 | calmodulin binding(GO:0005516) |
