Motif ID: Cbfb

Z-value: 0.372


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.143.0e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 2.551 ENSMUST00000168589.1
 Sla
src-like adaptor
chr14_+_101729907 2.261 ENSMUST00000100337.3
 Lmo7
LIM domain only 7
chr11_-_83649349 1.331 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr19_-_50678642 1.047 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chr2_+_32721055 0.941 ENSMUST00000074248.4
 Sh2d3c
SH2 domain containing 3C
chr4_-_6990774 0.860 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr19_-_50678485 0.855 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr5_+_104435112 0.697 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr14_-_101729690 0.693 ENSMUST00000066461.3
 Gm9922
predicted gene 9922
chr2_+_164948219 0.490 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr12_+_95692212 0.430 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr10_+_69925954 0.377 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
 Ank3


ankyrin 3, epithelial


chr2_+_172393794 0.329 ENSMUST00000099061.2
ENSMUST00000103073.2
 Cass4

Cas scaffolding protein family member 4

chr17_-_64331817 0.303 ENSMUST00000172733.1
ENSMUST00000172818.1
 Pja2

praja 2, RING-H2 motif containing

chr1_+_151755339 0.293 ENSMUST00000059498.5
 Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr5_+_24364804 0.267 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr8_+_90828820 0.264 ENSMUST00000109614.2
ENSMUST00000048665.6
 Chd9

chromodomain helicase DNA binding protein 9

chr2_+_72297895 0.209 ENSMUST00000144111.1
 Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr7_-_90129339 0.191 ENSMUST00000181189.1
 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr8_+_3353415 0.188 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr15_+_99393219 0.168 ENSMUST00000159209.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr6_+_136954521 0.139 ENSMUST00000137768.1
 Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr15_+_99392948 0.122 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
 Tmbim6


transmembrane BAX inhibitor motif containing 6


chr11_-_74724670 0.088 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr1_-_63176653 0.081 ENSMUST00000027111.8
ENSMUST00000168099.2
 Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr15_+_99393574 0.078 ENSMUST00000162624.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_-_17008647 0.074 ENSMUST00000102881.3
 Plek
pleckstrin
chr7_-_46795661 0.065 ENSMUST00000123725.1
 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr3_+_121291725 0.051 ENSMUST00000039442.7
 Alg14
asparagine-linked glycosylation 14
chr7_-_115824699 0.038 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr1_+_63176818 0.032 ENSMUST00000129339.1
 Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr15_+_99393610 0.023 ENSMUST00000159531.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr14_-_64949838 0.020 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
 Hmbox1





homeobox containing 1





chr4_+_10874498 0.016 ENSMUST00000080517.7
ENSMUST00000101504.2
 2610301B20Rik

RIKEN cDNA 2610301B20 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.4 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.7 GO:0033280 response to vitamin D(GO:0033280)
0.1 0.3 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.3 GO:0042805 actinin binding(GO:0042805)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)