Motif ID: Cdc5l

Z-value: 0.774


Transcription factors associated with Cdc5l:

Gene SymbolEntrez IDGene Name
Cdc5l ENSMUSG00000023932.8 Cdc5l

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_45433709-0.066.3e-01Click!


Activity profile for motif Cdc5l.

activity profile for motif Cdc5l


Sorted Z-values histogram for motif Cdc5l

Sorted Z-values for motif Cdc5l



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdc5l

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_31447383 11.637 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr18_-_22850738 10.119 ENSMUST00000092015.4
ENSMUST00000069215.6
 Nol4

nucleolar protein 4

chr12_+_29528382 7.715 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr2_+_65620829 6.284 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_-_112187766 5.865 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_107497762 5.765 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr5_+_107497718 5.403 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr5_+_66968416 4.803 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr9_-_55919605 4.450 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr9_-_96752822 4.234 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr9_-_112187898 3.796 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_66968559 3.781 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr10_+_17723220 3.602 ENSMUST00000038107.7
 Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_+_143640664 3.387 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr19_-_5797410 3.201 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr1_+_180111339 3.010 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr6_+_86526271 2.371 ENSMUST00000180896.1
 1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr12_+_74297474 1.786 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr10_-_127189981 1.587 ENSMUST00000019611.7
 Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr4_-_149126688 1.565 ENSMUST00000030815.2
 Cort
cortistatin
chrX_-_37104523 1.490 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr2_+_106695594 1.467 ENSMUST00000016530.7
 Mpped2
metallophosphoesterase domain containing 2
chrX_+_136822781 1.459 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1
chr1_-_30863256 1.455 ENSMUST00000088310.3
 Phf3
PHD finger protein 3
chr19_+_26749726 1.388 ENSMUST00000175842.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_64975762 1.117 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chrX_+_136822671 1.083 ENSMUST00000033800.6
 Plp1
proteolipid protein (myelin) 1
chr4_+_95967205 0.696 ENSMUST00000030306.7
 Hook1
hook homolog 1 (Drosophila)
chr11_-_50953745 0.691 ENSMUST00000162420.1
ENSMUST00000051159.2
 Prop1

paired like homeodomain factor 1

chr7_-_103741322 0.687 ENSMUST00000051346.2
 Olfr629
olfactory receptor 629
chr1_+_17601893 0.661 ENSMUST00000088476.2
 Pi15
peptidase inhibitor 15
chr7_+_130577334 0.555 ENSMUST00000059145.7
ENSMUST00000084513.4
 Tacc2

transforming, acidic coiled-coil containing protein 2

chr17_-_78684262 0.354 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr2_-_72986716 0.238 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr5_-_31220491 0.192 ENSMUST00000031032.7
 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr1_-_97761538 0.062 ENSMUST00000171129.1
 Ppip5k2
diphosphoinositol pentakisphosphate kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.5 11.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.9 3.6 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.8 3.2 GO:0035063 nuclear speck organization(GO:0035063)
0.2 3.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.7 GO:0060126 hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126)
0.2 9.7 GO:0034605 cellular response to heat(GO:0034605)
0.2 2.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 3.0 GO:0007097 nuclear migration(GO:0007097)
0.1 1.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 8.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0030953 astral microtubule organization(GO:0030953)
0.0 1.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 4.2 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.7 GO:0008333 endosome to lysosome transport(GO:0008333)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.6 GO:0031045 dense core granule(GO:0031045)
0.4 6.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.0 GO:0042641 actomyosin(GO:0042641)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.5 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 7.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 6.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 3.6 GO:0050693 LBD domain binding(GO:0050693)
0.4 3.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 11.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 4.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 10.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 9.3 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.0 GO:0000287 magnesium ion binding(GO:0000287)