Motif ID: Cdx2

Z-value: 0.768


Transcription factors associated with Cdx2:

Gene SymbolEntrez IDGene Name
Cdx2 ENSMUSG00000029646.3 Cdx2



Activity profile for motif Cdx2.

activity profile for motif Cdx2


Sorted Z-values histogram for motif Cdx2

Sorted Z-values for motif Cdx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 55 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_96455359 7.702 ENSMUST00000033553.7
 Heph
hephaestin
chr15_+_3270767 6.933 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr1_-_89933290 5.851 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr13_+_89540636 4.368 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr9_-_21989427 4.069 ENSMUST00000045726.6
 Rgl3
ral guanine nucleotide dissociation stimulator-like 3
chr1_+_12692430 3.891 ENSMUST00000180062.1
ENSMUST00000177608.1
 Sulf1

sulfatase 1

chr12_+_85473883 3.777 ENSMUST00000021674.6
 Fos
FBJ osteosarcoma oncogene
chr2_-_24048857 3.709 ENSMUST00000114497.1
 Hnmt
histamine N-methyltransferase
chr11_-_79504078 3.669 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein
chr16_-_44016387 3.322 ENSMUST00000036174.3
 Gramd1c
GRAM domain containing 1C
chr8_-_33843562 2.986 ENSMUST00000183062.1
 Rbpms
RNA binding protein gene with multiple splicing
chr19_-_34879452 2.975 ENSMUST00000036584.5
 Pank1
pantothenate kinase 1
chr1_-_163289214 2.904 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr9_-_45936049 2.875 ENSMUST00000034590.2
 Tagln
transgelin
chr3_+_126597415 2.682 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
 Camk2d


calcium/calmodulin-dependent protein kinase II, delta


chr3_+_126597299 2.610 ENSMUST00000106400.2
ENSMUST00000106401.1
 Camk2d

calcium/calmodulin-dependent protein kinase II, delta

chr15_-_50882806 2.601 ENSMUST00000184885.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_139582790 2.503 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr11_+_87663087 2.308 ENSMUST00000165679.1
 Rnf43
ring finger protein 43
chr10_+_88091070 2.250 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.7 GO:0006825 copper ion transport(GO:0006825)
1.0 6.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.8 5.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.1 5.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 4.4 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
1.0 3.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 3.8 GO:0035994 response to muscle stretch(GO:0035994)
0.2 3.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 3.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 3.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 3.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 2.9 GO:0048664 neuron fate determination(GO:0048664)
0.7 2.8 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 2.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 2.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.8 2.3 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.5 2.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.5 2.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 2.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.6 1.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.5 3.6 GO:0097452 GAIT complex(GO:0097452)
0.1 3.2 GO:0043194 axon initial segment(GO:0043194)
0.0 3.0 GO:0030118 clathrin coat(GO:0030118)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0016460 myosin II complex(GO:0016460)
0.1 1.1 GO:0061574 ASAP complex(GO:0061574)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
1.5 7.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 6.9 GO:0008430 selenium binding(GO:0008430)
0.7 5.3 GO:0031432 titin binding(GO:0031432)
0.2 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 4.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 3.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
1.2 3.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.6 3.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 3.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 2.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.3 GO:0005109 frizzled binding(GO:0005109)
0.0 2.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.4 2.2 GO:0045545 syndecan binding(GO:0045545)
0.2 2.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)