Motif ID: Cebpa_Cebpg

Z-value: 0.939

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpamm10_v2_chr7_+_35119285_351193010.678.9e-09Click!
Cebpgmm10_v2_chr7_-_35056467_35056556-0.383.2e-03Click!


Activity profile for motif Cebpa_Cebpg.

activity profile for motif Cebpa_Cebpg


Sorted Z-values histogram for motif Cebpa_Cebpg

Sorted Z-values for motif Cebpa_Cebpg



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Showing 1 to 20 of 145 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65970610 10.321 ENSMUST00000127387.1
 Clu
clusterin
chr14_+_65971049 10.059 ENSMUST00000128539.1
 Clu
clusterin
chr9_+_37367354 9.102 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr14_+_65971164 8.795 ENSMUST00000144619.1
 Clu
clusterin
chr3_+_19957037 8.407 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin


chr3_+_66219909 7.832 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr14_+_65970804 6.651 ENSMUST00000138191.1
 Clu
clusterin
chr7_-_103813913 6.509 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr4_+_136143497 5.921 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr2_+_102706356 5.582 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
 Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr1_+_169655493 4.164 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr7_-_79149042 4.060 ENSMUST00000032825.8
ENSMUST00000107409.3
 Mfge8

milk fat globule-EGF factor 8 protein

chr15_-_88978958 4.037 ENSMUST00000042594.6
ENSMUST00000109368.1
 Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr9_+_94669876 3.905 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_+_27447978 3.389 ENSMUST00000037399.9
ENSMUST00000108358.1
 Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr5_+_63812447 3.239 ENSMUST00000081747.3
 0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr1_+_134182404 3.201 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
 Chi3l1



chitinase 3-like 1



chr12_+_74297474 3.109 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr1_+_74542881 3.092 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
 Plcd4




phospholipase C, delta 4




chr6_+_17463749 3.043 ENSMUST00000115443.1
 Met
met proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.0 35.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.5 8.4 GO:0046688 response to copper ion(GO:0046688)
2.6 7.8 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 6.7 GO:0007050 cell cycle arrest(GO:0007050)
0.2 5.9 GO:0071398 cellular response to fatty acid(GO:0071398)
0.8 5.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 4.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 4.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.8 4.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.6 3.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.7 3.4 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 3.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.4 2.9 GO:0032264 IMP salvage(GO:0032264)
0.1 2.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.9 2.6 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.4 2.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 2.2 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 2.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 2.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 2.0 GO:0046039 GTP metabolic process(GO:0046039)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.1 35.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.3 8.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 7.8 GO:0055037 recycling endosome(GO:0055037)
1.6 6.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 5.8 GO:0030424 axon(GO:0030424)
0.2 5.6 GO:0030673 axolemma(GO:0030673)
0.0 4.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.1 GO:0030054 cell junction(GO:0030054)
0.0 3.0 GO:0036126 sperm flagellum(GO:0036126)
0.1 2.6 GO:0097440 apical dendrite(GO:0097440)
0.1 2.4 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0005938 cell cortex(GO:0005938)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.2 1.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.5 GO:0043203 axon hillock(GO:0043203)
0.0 1.5 GO:0043209 myelin sheath(GO:0043209)
0.5 1.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 35.8 GO:0051787 misfolded protein binding(GO:0051787)
1.7 8.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.6 7.8 GO:0001849 complement component C1q binding(GO:0001849)
1.6 6.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 5.9 GO:0005504 fatty acid binding(GO:0005504)
1.4 5.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 5.4 GO:0005096 GTPase activator activity(GO:0005096)
0.5 4.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 4.1 GO:0008565 protein transporter activity(GO:0008565)
0.5 3.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 3.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 3.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 3.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 2.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 2.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 2.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)