Motif ID: Cenpb

Z-value: 1.258


Transcription factors associated with Cenpb:

Gene SymbolEntrez IDGene Name
Cenpb ENSMUSG00000068267.4 Cenpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cenpbmm10_v2_chr2_-_131179985_131180092-0.637.2e-08Click!


Activity profile for motif Cenpb.

activity profile for motif Cenpb


Sorted Z-values histogram for motif Cenpb

Sorted Z-values for motif Cenpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cenpb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_98662227 38.435 ENSMUST00000099684.3
 Gm10801
predicted gene 10801
chr8_-_87959560 12.402 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr7_-_137314394 9.684 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr2_+_172550991 8.333 ENSMUST00000170744.1
 Tfap2c
transcription factor AP-2, gamma
chr16_-_17125106 7.175 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr12_+_59013379 7.143 ENSMUST00000021379.7
 Gemin2
gem (nuclear organelle) associated protein 2
chrX_-_143827391 7.132 ENSMUST00000087316.5
 Capn6
calpain 6
chr3_+_135307711 6.618 ENSMUST00000051849.8
 Slc9b2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr1_-_138848576 6.392 ENSMUST00000112030.2
 Lhx9
LIM homeobox protein 9
chr9_-_8004585 6.335 ENSMUST00000086580.5
ENSMUST00000065353.6
 Yap1

yes-associated protein 1

chr17_+_87282880 6.193 ENSMUST00000041110.5
ENSMUST00000125875.1
 Ttc7

tetratricopeptide repeat domain 7

chr13_+_48261427 6.169 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr11_+_101316917 6.075 ENSMUST00000151385.1
 Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr14_-_15438974 5.533 ENSMUST00000055211.4
 Lrrc3b
leucine rich repeat containing 3B
chr5_-_24730635 5.364 ENSMUST00000068693.5
 Wdr86
WD repeat domain 86
chr6_+_4755327 5.276 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr7_+_29983948 4.944 ENSMUST00000148442.1
 Zfp568
zinc finger protein 568
chr17_+_23679363 4.881 ENSMUST00000024699.2
 Cldn6
claudin 6
chr5_-_144358103 4.843 ENSMUST00000055190.7
 Baiap2l1
BAI1-associated protein 2-like 1
chr5_-_138170992 4.769 ENSMUST00000139983.1
 Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 131 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 14.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 8.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
2.8 8.3 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.2 8.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.9 7.9 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.8 7.0 GO:0042756 drinking behavior(GO:0042756)
0.2 6.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
2.2 6.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 6.5 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
1.3 6.4 GO:0035262 gonad morphogenesis(GO:0035262)
1.1 6.3 GO:0060242 contact inhibition(GO:0060242)
1.5 6.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.8 5.3 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 5.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
1.0 4.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 4.9 GO:0051601 exocyst localization(GO:0051601)
0.0 4.9 GO:0045216 cell-cell junction organization(GO:0045216)
0.3 4.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 4.8 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.9 4.7 GO:0070327 thyroid hormone transport(GO:0070327)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 30.0 GO:0005739 mitochondrion(GO:0005739)
0.7 11.1 GO:0042555 MCM complex(GO:0042555)
0.8 10.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 9.0 GO:0005643 nuclear pore(GO:0005643)
0.4 7.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.7 6.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5 6.1 GO:0008537 proteasome activator complex(GO:0008537)
0.5 6.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 6.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 5.3 GO:0005876 spindle microtubule(GO:0005876)
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.0 GO:0005925 focal adhesion(GO:0005925)
0.3 4.9 GO:0000145 exocyst(GO:0000145)
0.2 4.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 4.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 3.8 GO:0016234 inclusion body(GO:0016234)
1.2 3.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.4 GO:0044822 poly(A) RNA binding(GO:0044822)
0.3 12.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.5 11.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 9.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 7.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 6.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.8 6.5 GO:0008097 5S rRNA binding(GO:0008097)
0.3 6.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 6.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 6.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 5.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 5.3 GO:0043237 laminin-1 binding(GO:0043237)
0.5 5.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
1.2 4.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 4.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
1.1 4.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 4.5 GO:0005536 glucose binding(GO:0005536)
0.3 4.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 4.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.1 GO:0003746 translation elongation factor activity(GO:0003746)