Motif ID: Chd1_Pml

Z-value: 4.823

Transcription factors associated with Chd1_Pml:

Gene SymbolEntrez IDGene Name
Chd1 ENSMUSG00000023852.7 Chd1
Pml ENSMUSG00000036986.10 Pml

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pmlmm10_v2_chr9_-_58249660_58249672-0.201.2e-01Click!
Chd1mm10_v2_chr17_+_15704963_157049940.114.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Chd1_Pml

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84800024 144.665 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr8_-_84800344 114.172 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr15_-_66286224 99.528 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chrX_+_170009659 83.779 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr6_+_99692679 81.221 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr4_-_120287349 77.677 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr2_+_155775333 64.345 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chr6_-_32588192 61.577 ENSMUST00000115096.2
Plxna4
plexin A4
chr6_-_114042020 52.846 ENSMUST00000101045.3
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr11_-_6065737 51.998 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr16_-_67620880 51.635 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr4_+_124657646 50.811 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr12_-_4477138 50.486 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr1_-_56972437 49.571 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr15_-_12321899 48.356 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chrX_+_170009892 48.005 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr10_-_43174521 45.465 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr11_-_6065538 45.197 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr4_+_97777780 45.163 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr6_+_54816906 44.959 ENSMUST00000079869.6
Znrf2
zinc and ring finger 2
chr12_-_5375682 44.775 ENSMUST00000020958.8
Klhl29
kelch-like 29
chr16_-_67620805 42.370 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr1_-_56971762 42.200 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr9_-_98033181 41.953 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chrX_+_69360294 41.408 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr4_-_129121699 40.025 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr1_+_167001417 39.345 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr3_+_136670076 38.291 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_+_8801742 37.781 ENSMUST00000089085.2
Pde10a
phosphodiesterase 10A
chr11_-_69369377 37.637 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr1_-_119422239 36.696 ENSMUST00000038765.5
Inhbb
inhibin beta-B
chr15_-_25413752 36.601 ENSMUST00000058845.7
Basp1
brain abundant, membrane attached signal protein 1
chr7_+_123982799 35.914 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr10_+_39732099 35.726 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr17_+_6106880 35.671 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr10_+_127078886 35.558 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_-_133498538 35.241 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr6_-_88875035 35.149 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr9_-_86880414 34.782 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr5_+_37028329 34.749 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr2_+_90885860 33.609 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr17_+_86167777 33.457 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr18_+_69346143 33.451 ENSMUST00000114980.1
Tcf4
transcription factor 4
chrX_-_104201126 33.258 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr11_-_26210553 33.043 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr19_+_16132812 32.598 ENSMUST00000025541.5
Gnaq
guanine nucleotide binding protein, alpha q polypeptide
chrX_+_161717055 32.502 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr7_+_44310213 32.346 ENSMUST00000107938.1
Shank1
SH3/ankyrin domain gene 1
chr12_-_79007276 32.156 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr19_+_36554661 31.963 ENSMUST00000169036.2
ENSMUST00000047247.5
Hectd2

HECT domain containing 2

chr16_+_18127607 31.675 ENSMUST00000059589.5
Rtn4r
reticulon 4 receptor
chr11_+_77930800 31.638 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr5_-_22344690 31.516 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr5_-_122049822 31.504 ENSMUST00000111752.3
Cux2
cut-like homeobox 2
chr4_+_133039482 31.378 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr7_+_57591147 31.277 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr6_+_61180313 30.973 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr5_-_139129662 30.958 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr15_-_78120011 30.958 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr14_-_39472825 30.955 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr4_+_97777606 30.910 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr5_+_15934685 30.697 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr11_-_87359011 30.526 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr4_-_46991842 30.431 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_+_83779999 30.178 ENSMUST00000046168.5
Mpped1
metallophosphoesterase domain containing 1
chr3_+_105452326 29.989 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr15_+_83779975 29.884 ENSMUST00000163723.1
Mpped1
metallophosphoesterase domain containing 1
chr5_+_36868467 29.596 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr4_+_129985098 29.555 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr7_-_134938264 29.300 ENSMUST00000171394.1
Fam196a
family with sequence similarity 196, member A
chr5_+_125532377 29.115 ENSMUST00000031446.6
Tmem132b
transmembrane protein 132B
chr15_+_25414175 28.913 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr11_+_80477015 28.898 ENSMUST00000053413.10
ENSMUST00000147694.1
Cdk5r1

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

chr6_-_53068562 28.811 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr14_-_29721835 28.791 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr4_+_33924632 28.721 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr12_+_12262139 28.582 ENSMUST00000069066.6
ENSMUST00000069005.8
Fam49a

family with sequence similarity 49, member A

chr17_-_56140333 28.378 ENSMUST00000001256.4
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chrX_-_104201099 28.228 ENSMUST00000087879.4
C77370
expressed sequence C77370
chr6_+_115134899 28.065 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr18_+_69345721 27.892 ENSMUST00000078486.6
ENSMUST00000114982.1
Tcf4

transcription factor 4

chr15_+_89499598 27.886 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr4_+_107802277 27.728 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr16_+_44173271 27.486 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr6_+_86526271 27.477 ENSMUST00000180896.1
1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr9_-_53975246 27.388 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr3_+_18054258 27.300 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr6_+_54681687 27.093 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr2_-_162661075 26.564 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr7_-_46179929 26.546 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr4_+_32238713 26.540 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr11_+_104231390 26.529 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr13_-_101768154 26.481 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr11_+_24076529 26.413 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr4_-_129121234 26.368 ENSMUST00000030572.3
Hpca
hippocalcin
chr5_-_122050102 26.190 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr8_+_93810832 26.076 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr12_-_27342696 26.032 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr2_+_82053222 25.715 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr9_-_56635624 25.626 ENSMUST00000114256.1
Lingo1
leucine rich repeat and Ig domain containing 1
chr16_+_44173239 25.506 ENSMUST00000119746.1
Gm608
predicted gene 608
chr11_+_104231573 25.264 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr5_-_100159261 25.253 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr4_-_129121889 25.196 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr3_-_56183678 25.189 ENSMUST00000029374.6
Nbea
neurobeachin
chr6_-_148444336 25.169 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr2_-_181135103 25.155 ENSMUST00000149964.2
ENSMUST00000103050.3
ENSMUST00000081528.6
ENSMUST00000049792.8
ENSMUST00000103048.3
ENSMUST00000103047.3
ENSMUST00000129073.1
ENSMUST00000144592.1
ENSMUST00000139458.1
ENSMUST00000154164.1
ENSMUST00000123336.1
ENSMUST00000129361.1
ENSMUST00000103051.2
Kcnq2












potassium voltage-gated channel, subfamily Q, member 2












chr7_+_126823287 25.023 ENSMUST00000079423.5
Fam57b
family with sequence similarity 57, member B
chr1_-_33907721 24.930 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr9_-_98032983 24.910 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr6_-_13838432 24.844 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr8_+_26977336 24.735 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chrX_+_161717498 24.692 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chrY_+_90784738 24.690 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr17_+_6106464 24.609 ENSMUST00000142030.1
Tulp4
tubby like protein 4
chr15_+_40655020 24.173 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chrX_-_158043266 24.152 ENSMUST00000026750.8
ENSMUST00000112513.1
Cnksr2

connector enhancer of kinase suppressor of Ras 2

chr17_-_45549655 24.092 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr5_-_71095765 24.075 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr4_+_141368116 24.034 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr12_-_100725028 23.922 ENSMUST00000043599.6
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr14_-_30353468 23.790 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_-_70365052 23.560 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr4_-_22488296 23.491 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr17_+_46297406 23.418 ENSMUST00000061722.6
ENSMUST00000166280.1
Dlk2

delta-like 2 homolog (Drosophila)

chr4_-_91372028 23.340 ENSMUST00000107110.1
ENSMUST00000008633.8
ENSMUST00000107118.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr14_-_102982630 23.338 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr4_-_140246751 23.203 ENSMUST00000039331.8
Igsf21
immunoglobulin superfamily, member 21
chr3_-_88000350 23.070 ENSMUST00000090971.5
Bcan
brevican
chr6_+_103510874 22.997 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr5_+_121220191 22.942 ENSMUST00000119892.2
ENSMUST00000042614.6
Gm15800

predicted gene 15800

chr11_+_104231515 22.885 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr6_+_124996681 22.837 ENSMUST00000032479.4
Pianp
PILR alpha associated neural protein
chr10_+_13966268 22.798 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_18514802 22.749 ENSMUST00000090601.5
Cttnbp2
cortactin binding protein 2
chr1_-_3671498 22.748 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr8_+_111536492 22.698 ENSMUST00000168428.1
ENSMUST00000171182.1
Znrf1

zinc and ring finger 1

chr5_-_45857473 22.648 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr2_-_5714490 22.583 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr5_-_124249758 22.500 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr8_+_121730563 22.248 ENSMUST00000026357.5
Jph3
junctophilin 3
chr1_+_167001457 22.242 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr12_-_111908040 22.165 ENSMUST00000163747.2
ENSMUST00000054815.7
Ppp1r13b

protein phosphatase 1, regulatory (inhibitor) subunit 13B

chr8_-_36249292 22.114 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr11_-_108343917 22.025 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr11_-_86357570 21.875 ENSMUST00000043624.8
Med13
mediator complex subunit 13
chr6_-_120493807 21.826 ENSMUST00000178687.1
Cecr6
cat eye syndrome chromosome region, candidate 6
chr4_-_45530330 21.741 ENSMUST00000061986.5
Shb
src homology 2 domain-containing transforming protein B
chr3_+_107036156 21.737 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr18_+_67933257 21.654 ENSMUST00000063775.3
Ldlrad4
low density lipoprotein receptor class A domain containing 4
chr10_-_80387642 21.649 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)

chr5_+_110879788 21.635 ENSMUST00000156290.2
ENSMUST00000040111.9
Ttc28

tetratricopeptide repeat domain 28

chr1_-_72536930 21.615 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr14_-_73325773 21.604 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr11_+_104231465 21.484 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr6_-_88874597 21.463 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr15_+_66577536 21.346 ENSMUST00000048188.8
Phf20l1
PHD finger protein 20-like 1
chr8_+_70754679 21.324 ENSMUST00000110093.2
ENSMUST00000143118.1
ENSMUST00000034301.5
ENSMUST00000110090.1
Rab3a



RAB3A, member RAS oncogene family



chr6_-_124769548 21.302 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr2_-_33371486 21.296 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr2_-_84886692 21.030 ENSMUST00000054514.5
ENSMUST00000151799.1
Rtn4rl2

reticulon 4 receptor-like 2

chrX_+_73503074 20.985 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr4_-_82505274 20.970 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr2_-_33371400 20.951 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr11_+_98348404 20.937 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_-_95514570 20.795 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr17_+_8340710 20.760 ENSMUST00000163887.1
Prr18
proline rich region 18
chr14_-_103346765 20.753 ENSMUST00000159855.1
Mycbp2
MYC binding protein 2
chr3_+_136670679 20.752 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr5_+_15934762 20.704 ENSMUST00000115281.2
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr4_+_101496648 20.662 ENSMUST00000106930.1
ENSMUST00000154120.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr7_-_30445508 20.600 ENSMUST00000006828.7
Aplp1
amyloid beta (A4) precursor-like protein 1
chr12_+_71309876 20.596 ENSMUST00000061273.5
ENSMUST00000150639.1
Dact1

dapper homolog 1, antagonist of beta-catenin (xenopus)

chr4_-_123664725 20.542 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr11_-_116412965 20.464 ENSMUST00000100202.3
ENSMUST00000106398.2
Rnf157

ring finger protein 157

chr4_-_105109829 20.414 ENSMUST00000030243.7
Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr6_-_37299950 20.357 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr2_+_152081529 20.252 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr5_-_109558957 20.176 ENSMUST00000044579.7
Crlf2
cytokine receptor-like factor 2
chr9_+_57940104 20.009 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr9_+_59750876 19.999 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr17_+_69969217 19.981 ENSMUST00000060072.5
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr4_+_129984833 19.979 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr10_+_39732364 19.955 ENSMUST00000164763.1
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr4_+_42917234 19.830 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr15_-_76521902 19.811 ENSMUST00000164703.1
ENSMUST00000096365.3
Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr17_-_25433775 19.761 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr4_-_82505749 19.746 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr8_-_29219338 19.728 ENSMUST00000168630.2
Unc5d
unc-5 homolog D (C. elegans)
chr11_+_70844745 19.727 ENSMUST00000076270.6
ENSMUST00000179114.1
ENSMUST00000100928.4
ENSMUST00000177731.1
ENSMUST00000108533.3
ENSMUST00000081362.6
ENSMUST00000178245.1
Rabep1






rabaptin, RAB GTPase binding effector protein 1






chr4_-_148287927 19.635 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr11_+_50602072 19.597 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr4_+_155734800 19.516 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr9_+_95559817 19.421 ENSMUST00000079597.5
Paqr9
progestin and adipoQ receptor family member IX
chr2_+_128967383 19.334 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr13_-_32802849 19.308 ENSMUST00000057911.1
D930007J09Rik
RIKEN cDNA D930007J09 gene
chr16_-_20621255 19.218 ENSMUST00000052939.2
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr1_+_181352618 19.169 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr2_-_168741898 19.118 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr7_+_44384604 19.099 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
33.9 101.7 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
30.5 91.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
29.1 87.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
22.4 314.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
19.0 57.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
18.8 75.4 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
18.8 56.5 GO:0050975 sensory perception of touch(GO:0050975)
16.8 50.3 GO:0046959 habituation(GO:0046959)
16.6 49.8 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
15.6 31.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
13.6 54.3 GO:0097477 lateral motor column neuron migration(GO:0097477)
13.0 52.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
12.6 88.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
12.2 48.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
11.3 56.7 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
11.0 32.9 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
10.8 172.0 GO:0060081 membrane hyperpolarization(GO:0060081)
9.8 157.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
9.8 39.0 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
9.7 38.9 GO:0021586 pons maturation(GO:0021586)
9.7 9.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
9.7 48.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
9.5 47.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
9.4 28.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
9.3 27.8 GO:0016191 synaptic vesicle uncoating(GO:0016191) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
9.3 55.6 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
9.3 27.8 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
9.2 27.6 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
9.1 9.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
8.9 35.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
8.8 8.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
8.6 34.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
8.2 24.7 GO:0045924 regulation of female receptivity(GO:0045924)
8.1 96.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
8.0 23.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
7.9 71.3 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
7.9 23.6 GO:0071873 response to norepinephrine(GO:0071873)
7.8 38.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
7.7 61.5 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
7.6 61.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
7.4 37.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
7.4 36.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
7.3 65.9 GO:0042118 endothelial cell activation(GO:0042118)
7.3 21.9 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
6.9 27.5 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
6.7 114.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
6.6 19.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
6.6 13.2 GO:1900453 negative regulation of long term synaptic depression(GO:1900453)
6.5 6.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
6.4 19.1 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
6.3 63.3 GO:0023041 neuronal signal transduction(GO:0023041)
6.3 37.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
6.2 6.2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
6.2 24.7 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
6.2 18.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
6.1 18.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
6.1 6.1 GO:0097107 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107)
6.1 6.1 GO:0035811 negative regulation of urine volume(GO:0035811)
6.1 139.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
6.0 6.0 GO:0008355 olfactory learning(GO:0008355)
6.0 17.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
5.9 29.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
5.9 11.8 GO:0097494 regulation of vesicle size(GO:0097494)
5.7 5.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
5.7 17.2 GO:0007525 somatic muscle development(GO:0007525)
5.7 17.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
5.7 28.5 GO:0021960 anterior commissure morphogenesis(GO:0021960)
5.7 17.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
5.7 11.3 GO:2000852 regulation of corticosterone secretion(GO:2000852)
5.6 28.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
5.6 44.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
5.6 5.6 GO:0018307 enzyme active site formation(GO:0018307)
5.5 5.5 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
5.5 66.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
5.5 27.6 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
5.5 5.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
5.4 5.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
5.4 16.3 GO:0002159 desmosome assembly(GO:0002159)
5.3 42.4 GO:0097264 self proteolysis(GO:0097264)
5.3 15.8 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791)
5.2 20.8 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
5.2 10.4 GO:0034334 adherens junction maintenance(GO:0034334)
5.1 148.8 GO:0060074 synapse maturation(GO:0060074)
5.1 15.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
5.1 20.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
4.9 24.5 GO:0051012 microtubule sliding(GO:0051012)
4.8 52.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
4.7 18.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
4.7 23.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
4.6 13.9 GO:0031133 regulation of axon diameter(GO:0031133)
4.6 41.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
4.6 9.3 GO:0021852 pyramidal neuron migration(GO:0021852)
4.6 18.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
4.6 41.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
4.6 18.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
4.6 22.9 GO:0034183 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
4.6 36.6 GO:0010459 negative regulation of heart rate(GO:0010459)
4.5 31.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
4.5 4.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
4.5 17.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
4.5 22.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
4.4 8.8 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
4.4 13.2 GO:0019858 cytosine metabolic process(GO:0019858)
4.4 17.6 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
4.3 47.6 GO:0032482 Rab protein signal transduction(GO:0032482)
4.3 43.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
4.3 38.9 GO:0060134 prepulse inhibition(GO:0060134)
4.2 12.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
4.2 33.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
4.2 37.6 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
4.2 58.5 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
4.1 4.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
4.1 8.2 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
4.0 16.1 GO:1902669 positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
4.0 12.0 GO:0050915 sensory perception of sour taste(GO:0050915)
4.0 12.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
4.0 11.9 GO:0021546 rhombomere development(GO:0021546)
4.0 4.0 GO:2000830 vacuolar phosphate transport(GO:0007037) vitamin D3 metabolic process(GO:0070640) positive regulation of parathyroid hormone secretion(GO:2000830)
4.0 19.8 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
4.0 31.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
3.9 15.6 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
3.9 19.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
3.9 27.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
3.9 19.3 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
3.8 15.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
3.8 38.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
3.8 18.8 GO:0030242 pexophagy(GO:0030242)
3.7 15.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
3.7 15.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
3.7 14.9 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
3.7 73.8 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
3.7 3.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
3.7 14.7 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
3.7 14.7 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
3.7 33.0 GO:0044090 positive regulation of vacuole organization(GO:0044090)
3.7 11.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
3.6 138.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
3.6 7.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
3.6 14.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
3.6 43.5 GO:0070842 aggresome assembly(GO:0070842)
3.6 10.9 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
3.6 10.7 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
3.5 3.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
3.5 17.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
3.5 24.4 GO:0097324 melanocyte migration(GO:0097324)
3.4 20.7 GO:0072319 vesicle uncoating(GO:0072319)
3.4 3.4 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
3.4 44.6 GO:0071625 vocalization behavior(GO:0071625)
3.4 10.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
3.4 3.4 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
3.4 26.8 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
3.4 16.8 GO:0043314 negative regulation of cellular extravasation(GO:0002692) negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
3.3 10.0 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
3.3 16.5 GO:0006543 glutamine catabolic process(GO:0006543)
3.3 6.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
3.3 9.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
3.2 22.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
3.2 9.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
3.2 54.5 GO:0046069 cGMP catabolic process(GO:0046069)
3.2 28.8 GO:0031280 negative regulation of cyclase activity(GO:0031280)
3.2 3.2 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
3.2 60.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
3.2 69.6 GO:0048268 clathrin coat assembly(GO:0048268)
3.1 12.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
3.1 12.5 GO:0061010 gall bladder development(GO:0061010)
3.1 15.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
3.1 40.3 GO:0001964 startle response(GO:0001964)
3.1 30.8 GO:0071435 potassium ion export(GO:0071435)
3.1 18.5 GO:0051013 microtubule severing(GO:0051013)
3.0 9.0 GO:0021764 amygdala development(GO:0021764)
3.0 9.0 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
3.0 3.0 GO:0003383 apical constriction(GO:0003383)
3.0 15.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
3.0 14.9 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
3.0 9.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
2.9 29.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
2.9 11.7 GO:0010544 negative regulation of platelet activation(GO:0010544)
2.9 5.8 GO:0032847 regulation of cellular pH reduction(GO:0032847)
2.9 8.7 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
2.9 2.9 GO:0021604 cranial nerve structural organization(GO:0021604)
2.9 8.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
2.9 8.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
2.9 77.7 GO:2001222 regulation of neuron migration(GO:2001222)
2.9 5.8 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
2.9 28.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
2.9 17.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
2.8 2.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
2.8 22.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
2.8 17.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.8 8.5 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
2.8 11.3 GO:0060178 regulation of exocyst localization(GO:0060178)
2.8 25.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
2.8 16.9 GO:0005513 detection of calcium ion(GO:0005513)
2.8 2.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
2.8 5.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
2.8 8.3 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
2.8 11.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
2.8 33.1 GO:0008038 neuron recognition(GO:0008038)
2.8 11.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
2.7 11.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
2.7 16.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.7 5.5 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
2.7 2.7 GO:0070141 response to UV-A(GO:0070141)
2.7 8.2 GO:0045204 MAPK export from nucleus(GO:0045204)
2.7 13.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.7 8.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) protein myristoylation(GO:0018377)
2.7 13.3 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
2.7 29.2 GO:0045332 phospholipid translocation(GO:0045332)
2.6 7.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
2.6 2.6 GO:0046958 nonassociative learning(GO:0046958)
2.6 13.1 GO:0007256 activation of JNKK activity(GO:0007256)
2.6 2.6 GO:1900452 regulation of long term synaptic depression(GO:1900452)
2.6 10.3 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
2.6 5.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
2.6 7.7 GO:0072092 ureteric bud invasion(GO:0072092)
2.6 17.9 GO:0016584 nucleosome positioning(GO:0016584)
2.5 10.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.5 5.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
2.5 5.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511) negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
2.5 7.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
2.5 10.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
2.5 2.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
2.5 5.0 GO:0072289 metanephric nephron tubule formation(GO:0072289)
2.5 7.5 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
2.5 15.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
2.5 9.9 GO:0031642 negative regulation of myelination(GO:0031642)
2.5 2.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
2.4 21.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
2.4 33.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.4 4.8 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
2.4 14.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
2.4 4.8 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
2.4 14.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
2.4 12.0 GO:0046684 response to pyrethroid(GO:0046684)
2.4 12.0 GO:0015871 choline transport(GO:0015871)
2.4 16.7 GO:0030322 stabilization of membrane potential(GO:0030322)
2.4 4.8 GO:0014887 cardiac muscle adaptation(GO:0014887)
2.4 7.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
2.4 7.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
2.4 23.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
2.4 23.7 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
2.4 9.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
2.4 4.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
2.3 7.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
2.3 23.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
2.3 6.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.3 4.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
2.3 2.3 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
2.3 16.0 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
2.3 6.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
2.3 25.1 GO:0006857 oligopeptide transport(GO:0006857)
2.3 6.8 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
2.3 4.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.2 9.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
2.2 6.7 GO:2001258 negative regulation of cation channel activity(GO:2001258)
2.2 13.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.2 8.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.2 2.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
2.2 2.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
2.2 6.6 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
2.2 2.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
2.2 6.6 GO:0008228 opsonization(GO:0008228)
2.2 6.6 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
2.2 39.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
2.2 21.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
2.2 8.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
2.2 69.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
2.1 6.4 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
2.1 10.7 GO:0048102 autophagic cell death(GO:0048102)
2.1 14.9 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
2.1 2.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
2.1 19.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
2.1 6.4 GO:0030321 transepithelial chloride transport(GO:0030321) transepithelial ammonium transport(GO:0070634)
2.1 12.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
2.1 14.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
2.1 37.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
2.1 10.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
2.1 20.7 GO:0016082 synaptic vesicle priming(GO:0016082)
2.1 28.8 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
2.1 12.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
2.0 10.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
2.0 8.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
2.0 8.1 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
2.0 6.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.0 10.0 GO:0090168 Golgi reassembly(GO:0090168)
2.0 99.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.0 23.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
2.0 15.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.0 7.8 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
2.0 19.6 GO:0000042 protein targeting to Golgi(GO:0000042)
2.0 74.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
1.9 7.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.9 48.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
1.9 19.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.9 7.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.9 5.8 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.9 5.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.9 21.1 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
1.9 11.4 GO:0014850 response to muscle activity(GO:0014850)
1.9 3.8 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
1.9 51.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
1.9 5.6 GO:0071492 cellular response to UV-A(GO:0071492)
1.9 9.4 GO:0051684 maintenance of Golgi location(GO:0051684)
1.9 9.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.9 22.3 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.9 14.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.8 1.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
1.8 5.5 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
1.8 5.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.8 18.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
1.8 20.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.8 9.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.8 7.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.8 1.8 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
1.8 21.7 GO:1990403 embryonic brain development(GO:1990403)
1.8 7.2 GO:0033700 phospholipid efflux(GO:0033700)
1.8 5.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.8 7.2 GO:0035617 stress granule disassembly(GO:0035617)
1.8 17.9 GO:0014047 glutamate secretion(GO:0014047)
1.8 1.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.8 5.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
1.8 49.9 GO:0042220 response to cocaine(GO:0042220)
1.8 7.1 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
1.8 15.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
1.8 12.3 GO:0007296 vitellogenesis(GO:0007296)
1.7 8.7 GO:0019236 response to pheromone(GO:0019236)
1.7 5.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
1.7 3.4 GO:0001922 B-1 B cell homeostasis(GO:0001922)
1.7 3.4 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
1.7 5.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.7 3.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
1.7 5.1 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
1.7 1.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
1.7 11.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
1.7 1.7 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
1.7 3.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.7 5.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.7 11.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.7 1.7 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
1.6 11.5 GO:0061157 mRNA destabilization(GO:0061157)
1.6 6.6 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
1.6 11.4 GO:0032411 positive regulation of transporter activity(GO:0032411)
1.6 1.6 GO:0051956 negative regulation of amino acid transport(GO:0051956)
1.6 3.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
1.6 4.8 GO:0051542 elastin biosynthetic process(GO:0051542)
1.6 11.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
1.6 3.2 GO:2000821 regulation of grooming behavior(GO:2000821)
1.6 11.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.6 6.3 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.6 12.5 GO:0006265 DNA topological change(GO:0006265)
1.6 1.6 GO:0007143 female meiotic division(GO:0007143)
1.6 51.5 GO:0061512 protein localization to cilium(GO:0061512)
1.6 4.7 GO:0016598 protein arginylation(GO:0016598)
1.5 1.5 GO:0035993 deltoid tuberosity development(GO:0035993)
1.5 3.1 GO:0001543 ovarian follicle rupture(GO:0001543)
1.5 7.7 GO:0032486 Rap protein signal transduction(GO:0032486)
1.5 6.2 GO:0097298 regulation of nucleus size(GO:0097298)
1.5 7.7 GO:0046549 retinal cone cell development(GO:0046549)
1.5 4.6 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
1.5 4.6 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
1.5 10.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.5 7.5 GO:0006382 adenosine to inosine editing(GO:0006382)
1.5 7.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
1.5 4.5 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
1.5 4.5 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.5 3.0 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
1.5 3.0 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
1.5 4.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.5 3.0 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
1.5 5.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.5 7.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.5 7.3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
1.5 2.9 GO:0090494 catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
1.5 11.7 GO:0048520 positive regulation of behavior(GO:0048520)
1.5 2.9 GO:0007258 JUN phosphorylation(GO:0007258)
1.5 14.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
1.4 7.2 GO:0034421 post-translational protein acetylation(GO:0034421)
1.4 44.7 GO:0014044 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
1.4 1.4 GO:0097212 lysosomal membrane organization(GO:0097212)
1.4 4.3 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
1.4 7.2 GO:0097242 beta-amyloid clearance(GO:0097242)
1.4 4.3 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
1.4 34.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
1.4 1.4 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
1.4 21.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
1.4 4.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
1.4 19.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
1.4 9.8 GO:0090527 actin filament reorganization(GO:0090527)
1.4 4.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
1.4 1.4 GO:0001927 exocyst assembly(GO:0001927)
1.4 47.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.4 4.2 GO:0032596 protein transport into membrane raft(GO:0032596)
1.4 19.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
1.4 2.8 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.4 11.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.4 12.4 GO:0045109 intermediate filament organization(GO:0045109)
1.4 5.5 GO:0006041 glucosamine metabolic process(GO:0006041)
1.4 5.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.4 6.8 GO:0006622 protein targeting to lysosome(GO:0006622)
1.4 1.4 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
1.4 21.7 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
1.4 2.7 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.4 2.7 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
1.3 4.0 GO:0048388 endosomal lumen acidification(GO:0048388)
1.3 5.4 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.3 52.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
1.3 9.4 GO:2000272 negative regulation of receptor activity(GO:2000272)
1.3 2.7 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
1.3 29.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
1.3 9.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
1.3 5.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
1.3 7.9 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
1.3 5.3 GO:0044565 dendritic cell proliferation(GO:0044565)
1.3 11.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.3 3.9 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.3 3.9 GO:2000834 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
1.3 11.6 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
1.3 2.6 GO:0071071 regulation of phospholipid biosynthetic process(GO:0071071)
1.3 18.0 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.3 1.3 GO:0002432 granuloma formation(GO:0002432)
1.3 1.3 GO:0000710 meiotic mismatch repair(GO:0000710)
1.3 10.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
1.3 8.9 GO:0071318 cellular response to ATP(GO:0071318)
1.3 63.3 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
1.3 1.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
1.3 12.5 GO:1901621 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.2 1.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
1.2 11.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.2 9.8 GO:0086026 atrial cardiac muscle cell action potential(GO:0086014) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
1.2 13.4 GO:0002021 response to dietary excess(GO:0002021)
1.2 18.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
1.2 3.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
1.2 1.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
1.2 3.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.2 40.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
1.2 6.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.2 8.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
1.2 7.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.2 11.9 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
1.2 11.9 GO:0007220 Notch receptor processing(GO:0007220)
1.2 14.2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.2 2.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.2 4.7 GO:0001771 immunological synapse formation(GO:0001771)
1.2 14.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.2 7.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.2 3.5 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
1.2 2.3 GO:0060025 regulation of synaptic activity(GO:0060025)
1.2 2.3 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
1.1 17.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
1.1 3.4 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
1.1 111.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
1.1 8.0 GO:1904424 regulation of GTP binding(GO:1904424)
1.1 5.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.1 5.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
1.1 159.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.1 5.7 GO:0046416 D-amino acid metabolic process(GO:0046416)
1.1 1.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
1.1 16.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
1.1 13.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.1 7.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
1.1 2.2 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
1.1 34.0 GO:0045921 positive regulation of exocytosis(GO:0045921)
1.1 2.2 GO:0061043 regulation of vascular wound healing(GO:0061043)
1.1 19.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
1.1 1.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
1.1 14.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.1 3.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
1.1 2.1 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
1.1 5.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.1 4.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.1 16.8 GO:0045214 sarcomere organization(GO:0045214)
1.1 4.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.1 8.4 GO:0002931 response to ischemia(GO:0002931)
1.0 6.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.0 12.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
1.0 1.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
1.0 3.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.0 3.0 GO:0097309 cap1 mRNA methylation(GO:0097309)
1.0 9.8 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.0 2.0 GO:0035973 aggrephagy(GO:0035973)
1.0 1.0 GO:0090148 membrane fission(GO:0090148)
1.0 5.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
1.0 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.0 10.5 GO:0035418 protein localization to synapse(GO:0035418)
0.9 2.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.9 5.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.9 7.5 GO:0006903 vesicle targeting(GO:0006903)
0.9 2.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.9 11.1 GO:0097352 autophagosome maturation(GO:0097352)
0.9 4.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.9 1.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.9 1.8 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.9 3.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.9 4.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.9 6.4 GO:0032328 alanine transport(GO:0032328)
0.9 4.5 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.9 5.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.9 1.8 GO:0070417 cellular response to cold(GO:0070417)
0.9 13.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.9 1.8 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.9 1.8 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.9 6.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.9 6.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.9 4.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.9 2.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.9 0.9 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.9 12.9 GO:0090102 cochlea development(GO:0090102)
0.9 17.9 GO:0006491 N-glycan processing(GO:0006491)
0.8 6.7 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.8 5.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.8 5.0 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001)
0.8 2.5 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.8 6.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.8 4.1 GO:0016322 neuron remodeling(GO:0016322)
0.8 2.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.8 17.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.8 4.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.8 3.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.8 0.8 GO:0001963 synaptic transmission, dopaminergic(GO:0001963)
0.8 0.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.8 3.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.8 1.6 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.8 0.8 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.8 7.9 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.8 3.1 GO:0014889 muscle atrophy(GO:0014889)
0.8 1.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.8 2.4 GO:0046541 saliva secretion(GO:0046541)
0.8 1.6 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.8 4.7 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.8 2.3 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.8 44.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.8 2.3 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.8 4.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.8 2.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.8 2.3 GO:0021592 fourth ventricle development(GO:0021592)
0.8 5.3 GO:0051014 actin filament severing(GO:0051014)
0.8 4.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.8 0.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.8 3.0 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.8 0.8 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.8 4.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.7 1.5 GO:1990035 calcium ion import into cell(GO:1990035)
0.7 5.2 GO:0007097 nuclear migration(GO:0007097)
0.7 0.7 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.7 3.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 3.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.7 8.9 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.7 2.2 GO:0010869 regulation of receptor biosynthetic process(GO:0010869)
0.7 3.7 GO:0030259 lipid glycosylation(GO:0030259)
0.7 16.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.7 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.7 36.3 GO:0007612 learning(GO:0007612)
0.7 2.9 GO:0019228 neuronal action potential(GO:0019228)
0.7 9.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.7 1.4 GO:0043379 memory T cell differentiation(GO:0043379)
0.7 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.7 0.7 GO:0051541 elastin metabolic process(GO:0051541)
0.7 0.7 GO:0031645 negative regulation of neurological system process(GO:0031645)
0.7 0.7 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.7 1.4 GO:0051409 response to nitrosative stress(GO:0051409)
0.7 2.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.7 2.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.7 6.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.7 4.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.7 2.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.7 0.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) negative regulation of interleukin-1 secretion(GO:0050711) oligodendrocyte apoptotic process(GO:0097252)
0.7 4.8 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.7 1.4 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.7 2.7 GO:0035608 protein deglutamylation(GO:0035608)
0.7 7.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.7 3.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.7 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.7 3.4 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.7 6.0 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.7 5.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.7 3.3 GO:0051036 regulation of endosome size(GO:0051036)
0.7 2.0 GO:0030070 insulin processing(GO:0030070)
0.7 5.2 GO:0033572 transferrin transport(GO:0033572)
0.7 4.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.7 2.6 GO:0061718 NADH regeneration(GO:0006735) regulation of anion channel activity(GO:0010359) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.7 3.9 GO:0015791 polyol transport(GO:0015791)
0.7 0.7 GO:0003093 regulation of glomerular filtration(GO:0003093)
0.7 4.6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.6 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.6 1.9 GO:0043615 astrocyte cell migration(GO:0043615)
0.6 1.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.6 3.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.6 8.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.6 0.6 GO:0060022 hard palate development(GO:0060022)
0.6 1.2 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.6 7.5 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.6 3.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.6 16.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.6 0.6 GO:0032800 receptor biosynthetic process(GO:0032800)
0.6 3.0 GO:0050716 regulation of interleukin-1 secretion(GO:0050704) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.6 1.8 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.6 1.8 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.6 1.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.6 1.2 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.6 4.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 1.2 GO:1900424 regulation of defense response to bacterium(GO:1900424)
0.6 0.6 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.6 2.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.6 1.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.6 1.8 GO:0099504 synaptic vesicle cycle(GO:0099504)
0.6 5.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.6 2.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.6 0.6 GO:1902837 amino acid import into cell(GO:1902837)
0.6 2.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.6 13.4 GO:0007041 lysosomal transport(GO:0007041)
0.6 2.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.6 2.9 GO:0006689 ganglioside catabolic process(GO:0006689)
0.6 2.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.6 2.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.6 9.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 2.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.6 3.4 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.6 7.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.6 20.1 GO:0000045 autophagosome assembly(GO:0000045)
0.6 0.6 GO:0070375 ERK5 cascade(GO:0070375)
0.6 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.6 3.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.6 1.7 GO:0060468 prevention of polyspermy(GO:0060468)
0.5 2.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.5 2.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 14.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.5 6.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.5 2.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.5 1.0 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.5 11.5 GO:0007595 lactation(GO:0007595)
0.5 1.0 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.5 2.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.5 4.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.5 1.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.5 21.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.5 4.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 1.5 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.5 8.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.5 0.5 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.5 1.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.5 13.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.5 1.0 GO:0010820 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.5 2.5 GO:0048278 vesicle docking(GO:0048278)
0.5 2.5 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.5 3.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 2.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.5 3.4 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.5 0.5 GO:0040009 regulation of growth rate(GO:0040009)
0.5 1.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.5 6.7 GO:0007020 microtubule nucleation(GO:0007020)
0.5 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.5 4.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.5 3.3 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.5 1.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.5 1.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.5 1.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.5 1.8 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.5 6.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 1.4 GO:0046104 thymidine metabolic process(GO:0046104)
0.5 2.7 GO:0006172 ADP biosynthetic process(GO:0006172)
0.5 1.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.5 12.2 GO:0018345 protein palmitoylation(GO:0018345)
0.5 1.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.5 2.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 1.3 GO:0051026 chiasma assembly(GO:0051026)
0.4 1.3 GO:0019085 early viral transcription(GO:0019085)
0.4 24.4 GO:0006906 vesicle fusion(GO:0006906)
0.4 2.7 GO:0007616 long-term memory(GO:0007616)
0.4 0.4 GO:0039535 regulation of RIG-I signaling pathway(GO:0039535)
0.4 8.6 GO:0016578 histone deubiquitination(GO:0016578)
0.4 1.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.4 3.8 GO:0009404 toxin metabolic process(GO:0009404)
0.4 2.5 GO:0042755 eating behavior(GO:0042755)
0.4 2.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.4 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 0.4 GO:0009188 ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.4 6.3 GO:0008088 axo-dendritic transport(GO:0008088)
0.4 4.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.4 0.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.4 8.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.4 0.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.4 2.0 GO:0007603 phototransduction, visible light(GO:0007603)
0.4 2.8 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 3.7 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.4 1.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.4 0.8 GO:2000427 regulation of apoptotic cell clearance(GO:2000425) positive regulation of apoptotic cell clearance(GO:2000427)
0.4 2.0 GO:1901678 iron coordination entity transport(GO:1901678)
0.4 1.6 GO:0006983 ER overload response(GO:0006983)
0.4 2.3 GO:0070995 NADPH oxidation(GO:0070995)
0.4 4.6 GO:0051668 localization within membrane(GO:0051668)
0.4 17.0 GO:0016579 protein deubiquitination(GO:0016579)
0.4 1.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.4 5.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 3.0 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.4 3.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.4 4.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.4 4.1 GO:0031297 replication fork processing(GO:0031297)
0.4 1.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 1.8 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 11.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 22.5 GO:0036503 ERAD pathway(GO:0036503)
0.4 0.7 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.4 1.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.4 1.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 0.4 GO:0044849 estrous cycle(GO:0044849)
0.4 6.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.4 2.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.3 3.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 2.1 GO:0030035 microspike assembly(GO:0030035)
0.3 1.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 2.1 GO:0021670 lateral ventricle development(GO:0021670)
0.3 1.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.3 1.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 8.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 3.4 GO:0006012 galactose metabolic process(GO:0006012)
0.3 0.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 42.4 GO:0007018 microtubule-based movement(GO:0007018)
0.3 0.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.3 1.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 9.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.3 3.8 GO:0097300 programmed necrotic cell death(GO:0097300)
0.3 0.3 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.3 0.6 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.3 2.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 1.2 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.3 2.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 2.1 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.3 2.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.3 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.3 4.6 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.3 2.9 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.3 1.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.7 GO:0048305 immunoglobulin secretion(GO:0048305)
0.3 1.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 0.6 GO:0032570 response to progesterone(GO:0032570)
0.3 2.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 4.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.3 2.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 1.6 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.3 0.3 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.3 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.3 1.3 GO:0016239 positive regulation of macroautophagy(GO:0016239) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.3 2.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.3 7.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.3 1.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 1.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 2.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 0.5 GO:0009838 abscission(GO:0009838)
0.3 1.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.3 5.1 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.3 0.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 1.2 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.2 1.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 1.5 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 1.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.9 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 0.9 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.2 0.9 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.2 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.2 1.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.3 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.2 1.6 GO:0080009 mRNA methylation(GO:0080009)
0.2 2.2 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.2 4.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 1.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.2 1.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 1.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 0.6 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 0.9 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.2 1.3 GO:0031665 negative regulation of response to biotic stimulus(GO:0002832) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 0.4 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 2.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 0.6 GO:0051601 exocyst localization(GO:0051601)
0.2 1.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 3.1 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.8 GO:0030578 PML body organization(GO:0030578)
0.2 0.4 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 0.8 GO:0008206 bile acid metabolic process(GO:0008206)
0.2 0.8 GO:0002347 response to tumor cell(GO:0002347)
0.2 0.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.7 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.4 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.2 3.6 GO:0006829 zinc II ion transport(GO:0006829)
0.2 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 0.6 GO:0070230 positive regulation of lymphocyte apoptotic process(GO:0070230)
0.2 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 6.8 GO:0007338 single fertilization(GO:0007338)
0.1 3.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.7 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.2 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.1 0.4 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.2 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.1 0.5 GO:0044110 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 1.9 GO:0097581 lamellipodium organization(GO:0097581)
0.1 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 1.1 GO:0036065 fucosylation(GO:0036065)
0.1 0.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.8 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 5.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.4 GO:1901216 positive regulation of neuron death(GO:1901216)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.1 0.9 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 0.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.1 GO:0071549 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.2 GO:0001881 receptor recycling(GO:0001881)
0.1 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.7 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0032743 positive regulation of interleukin-2 production(GO:0032743)
0.1 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 1.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0090313 regulation of protein targeting to membrane(GO:0090313) positive regulation of protein targeting to membrane(GO:0090314)
0.0 0.5 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.8 GO:0006497 protein lipidation(GO:0006497)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 73.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
14.6 14.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
13.8 55.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
12.5 75.2 GO:0005955 calcineurin complex(GO:0005955)
12.5 37.5 GO:0042642 actomyosin, myosin complex part(GO:0042642)
11.1 110.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
10.7 32.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
10.3 102.7 GO:0044327 dendritic spine head(GO:0044327)
9.6 38.3 GO:0043511 inhibin complex(GO:0043511)
9.2 27.6 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
8.9 88.6 GO:0045298 tubulin complex(GO:0045298)
8.4 25.2 GO:0048179 activin receptor complex(GO:0048179)
8.3 33.0 GO:0044307 dendritic branch(GO:0044307)
8.1 8.1 GO:0098984 neuron to neuron synapse(GO:0098984)
7.4 36.9 GO:0030314 junctional membrane complex(GO:0030314)
6.8 205.5 GO:0043194 axon initial segment(GO:0043194)
6.8 20.3 GO:0014802 terminal cisterna(GO:0014802)
6.6 26.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
6.6 72.4 GO:0002116 semaphorin receptor complex(GO:0002116)
6.5 6.5 GO:1902737 dendritic filopodium(GO:1902737)
6.1 18.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
6.0 78.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
6.0 214.6 GO:0032809 neuronal cell body membrane(GO:0032809)
5.9 94.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
5.7 5.7 GO:0030137 COPI-coated vesicle(GO:0030137)
5.6 202.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
5.6 16.8 GO:0044194 cytolytic granule(GO:0044194)
5.6 11.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
5.4 27.2 GO:1990761 growth cone lamellipodium(GO:1990761)
5.4 10.8 GO:0060187 cell pole(GO:0060187)
5.3 47.5 GO:0000813 ESCRT I complex(GO:0000813)
4.9 29.6 GO:0005883 neurofilament(GO:0005883)
4.7 23.4 GO:0044316 cone cell pedicle(GO:0044316)
4.7 14.0 GO:1990075 periciliary membrane compartment(GO:1990075)
4.5 162.2 GO:0048786 presynaptic active zone(GO:0048786)
4.5 4.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
4.4 75.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
4.2 112.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
4.1 28.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
4.0 12.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
3.9 19.6 GO:0036449 microtubule minus-end(GO:0036449)
3.9 19.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.8 57.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
3.8 68.8 GO:0042734 presynaptic membrane(GO:0042734)
3.8 45.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
3.8 11.3 GO:0032437 cuticular plate(GO:0032437)
3.7 114.2 GO:0051233 spindle midzone(GO:0051233)
3.7 11.0 GO:0031251 PAN complex(GO:0031251)
3.6 68.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
3.6 3.6 GO:0042588 zymogen granule(GO:0042588)
3.4 55.1 GO:0030673 axolemma(GO:0030673)
3.4 17.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
3.3 29.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.3 9.8 GO:0043083 synaptic cleft(GO:0043083)
3.2 32.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
3.2 9.5 GO:0044308 axonal spine(GO:0044308)
3.1 9.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
3.0 93.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
3.0 182.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
2.9 14.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
2.9 11.5 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
2.9 8.6 GO:0030056 hemidesmosome(GO:0030056)
2.8 2.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
2.7 29.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
2.7 10.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
2.6 34.4 GO:0031209 SCAR complex(GO:0031209)
2.6 36.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
2.6 7.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.6 10.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.5 10.1 GO:0000322 storage vacuole(GO:0000322)
2.5 5.0 GO:0033268 node of Ranvier(GO:0033268)
2.5 7.5 GO:0005927 muscle tendon junction(GO:0005927)
2.4 2.4 GO:0098793 presynapse(GO:0098793)
2.3 146.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
2.3 9.2 GO:0032280 symmetric synapse(GO:0032280)
2.3 54.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
2.2 2.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.2 11.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.2 15.4 GO:0070695 FHF complex(GO:0070695)
2.2 161.3 GO:0043198 dendritic shaft(GO:0043198)
2.1 173.7 GO:0043195 terminal bouton(GO:0043195)
2.1 4.2 GO:0001739 sex chromatin(GO:0001739)
2.1 30.9 GO:0034704 calcium channel complex(GO:0034704)
2.0 394.5 GO:0045211 postsynaptic membrane(GO:0045211)
2.0 6.0 GO:0097433 dense body(GO:0097433)
2.0 6.0 GO:0005940 septin ring(GO:0005940)
1.9 5.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.9 102.3 GO:0005905 clathrin-coated pit(GO:0005905)
1.9 11.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.9 9.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.8 3.7 GO:0033263 CORVET complex(GO:0033263)
1.8 53.1 GO:0031901 early endosome membrane(GO:0031901)
1.8 3.5 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
1.7 46.7 GO:0035371 microtubule plus-end(GO:0035371)
1.7 15.2 GO:0070688 MLL5-L complex(GO:0070688)
1.6 197.5 GO:0031225 anchored component of membrane(GO:0031225)
1.6 116.8 GO:0043204 perikaryon(GO:0043204)
1.6 198.7 GO:0070382 exocytic vesicle(GO:0070382)
1.6 15.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.6 75.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.5 7.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.5 26.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
1.5 4.4 GO:0031430 M band(GO:0031430)
1.4 17.4 GO:0044666 MLL3/4 complex(GO:0044666)
1.4 140.7 GO:0055037 recycling endosome(GO:0055037)
1.4 22.1 GO:0097060 synaptic membrane(GO:0097060)
1.4 6.8 GO:0035189 Rb-E2F complex(GO:0035189)
1.3 6.7 GO:0032807 DNA ligase IV complex(GO:0032807)
1.3 6.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
1.3 16.1 GO:0000124 SAGA complex(GO:0000124)
1.3 2.7 GO:0030870 Mre11 complex(GO:0030870)
1.3 13.3 GO:0061700 GATOR2 complex(GO:0061700)
1.3 5.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.3 6.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
1.3 2.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.3 21.5 GO:0030014 CCR4-NOT complex(GO:0030014)
1.2 6.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.2 7.3 GO:0030127 COPII vesicle coat(GO:0030127)
1.2 19.5 GO:0001750 photoreceptor outer segment(GO:0001750)
1.2 3.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
1.2 4.8 GO:0033269 internode region of axon(GO:0033269)
1.2 3.5 GO:0031417 NatC complex(GO:0031417)
1.1 17.0 GO:0043034 costamere(GO:0043034)
1.1 2.3 GO:0002142 stereocilia ankle link complex(GO:0002142)
1.1 3.4 GO:0031094 platelet dense tubular network(GO:0031094)
1.1 2.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371) UBC13-MMS2 complex(GO:0031372)
1.1 1.1 GO:0030658 transport vesicle membrane(GO:0030658)
1.1 2.2 GO:1903349 omegasome membrane(GO:1903349)
1.1 11.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
1.1 3.3 GO:0001940 male pronucleus(GO:0001940)
1.1 18.7 GO:0097228 sperm principal piece(GO:0097228)
1.1 7.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
1.1 2.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.0 8.3 GO:0030008 TRAPP complex(GO:0030008)
1.0 2.1 GO:0070847 core mediator complex(GO:0070847)
1.0 3.1 GO:0043020 NADPH oxidase complex(GO:0043020)
1.0 14.3 GO:0042101 T cell receptor complex(GO:0042101)
1.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
1.0 3.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.0 7.0 GO:0000145 exocyst(GO:0000145)
1.0 2.9 GO:0045098 type III intermediate filament(GO:0045098)
0.9 4.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.9 119.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.9 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.9 1.8 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.9 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.9 11.7 GO:0005614 interstitial matrix(GO:0005614)
0.9 5.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.9 1.8 GO:0005683 U7 snRNP(GO:0005683)
0.9 15.5 GO:0001891 phagocytic cup(GO:0001891)
0.8 5.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.8 23.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.8 1.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.8 30.4 GO:0030139 endocytic vesicle(GO:0030139)
0.8 6.5 GO:0042382 paraspeckles(GO:0042382)
0.8 3.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.8 1.6 GO:0016939 kinesin II complex(GO:0016939)
0.8 2.4 GO:0055087 Ski complex(GO:0055087)
0.8 44.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.8 106.4 GO:0030427 site of polarized growth(GO:0030427)
0.8 29.8 GO:0005776 autophagosome(GO:0005776)
0.8 86.6 GO:0005802 trans-Golgi network(GO:0005802)
0.8 31.6 GO:0008180 COP9 signalosome(GO:0008180)
0.7 5.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.7 2.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.7 2.8 GO:0097227 sperm annulus(GO:0097227)
0.7 18.8 GO:0031201 SNARE complex(GO:0031201)
0.7 2.1 GO:0071797 LUBAC complex(GO:0071797)
0.7 9.0 GO:0010369 chromocenter(GO:0010369)
0.7 26.8 GO:0035869 ciliary transition zone(GO:0035869)
0.7 3.4 GO:0002080 acrosomal membrane(GO:0002080)
0.7 3.3 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.6 4.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.6 7.1 GO:0031672 A band(GO:0031672)
0.6 5.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.6 5.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.6 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 256.6 GO:0005768 endosome(GO:0005768)
0.6 27.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.6 1.2 GO:0071439 clathrin complex(GO:0071439)
0.6 9.1 GO:0097440 apical dendrite(GO:0097440)
0.6 1.7 GO:0030061 mitochondrial crista(GO:0030061)
0.6 4.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 10.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.6 1.7 GO:0031084 BLOC-2 complex(GO:0031084)
0.5 3.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.5 0.5 GO:0002141 stereocilia ankle link(GO:0002141)
0.5 2.1 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.5 2.0 GO:0032982 myosin filament(GO:0032982)
0.5 2.4 GO:0097449 astrocyte projection(GO:0097449)
0.5 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 17.5 GO:0005871 kinesin complex(GO:0005871)
0.5 4.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 2.2 GO:0042583 chromaffin granule(GO:0042583)
0.4 5.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.4 9.3 GO:0005685 U1 snRNP(GO:0005685)
0.4 5.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.4 4.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.4 8.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 2.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 2.8 GO:0060077 inhibitory synapse(GO:0060077)
0.4 0.8 GO:0001533 cornified envelope(GO:0001533)
0.4 10.9 GO:0009925 basal plasma membrane(GO:0009925)
0.4 9.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.4 5.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 19.1 GO:0036064 ciliary basal body(GO:0036064)
0.4 4.4 GO:0043596 nuclear replication fork(GO:0043596)
0.4 1.8 GO:0032433 filopodium tip(GO:0032433)
0.3 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 1.4 GO:0035339 SPOTS complex(GO:0035339)
0.3 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.3 2.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 3.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 3.6 GO:0031931 TORC1 complex(GO:0031931)
0.3 0.6 GO:0030478 actin cap(GO:0030478)
0.3 4.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 57.7 GO:0000139 Golgi membrane(GO:0000139)
0.3 10.7 GO:0035861 site of double-strand break(GO:0035861)
0.3 8.2 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.3 3.7 GO:0016589 NURF complex(GO:0016589)
0.3 1.2 GO:0030315 T-tubule(GO:0030315)
0.3 1.2 GO:0072487 MSL complex(GO:0072487)
0.3 0.9 GO:0070939 Dsl1p complex(GO:0070939)
0.3 0.9 GO:1990879 CST complex(GO:1990879)
0.3 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 2.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 2.0 GO:0000812 Swr1 complex(GO:0000812)
0.3 2.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 15.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 0.5 GO:0051286 cell tip(GO:0051286)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.8 GO:0034464 BBSome(GO:0034464)
0.2 2.9 GO:0017119 Golgi transport complex(GO:0017119)
0.2 625.9 GO:0016021 integral component of membrane(GO:0016021)
0.2 2.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 18.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.9 GO:0031298 replication fork protection complex(GO:0031298)
0.2 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.7 GO:0030904 retromer complex(GO:0030904)
0.2 0.9 GO:0097361 CIA complex(GO:0097361)
0.2 4.7 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 0.5 GO:0001652 granular component(GO:0001652)
0.2 2.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 6.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.1 GO:0005774 vacuolar membrane(GO:0005774)
0.1 19.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.2 GO:0071920 cleavage body(GO:0071920)
0.1 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.7 67.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
15.0 59.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
13.9 55.6 GO:0038025 reelin receptor activity(GO:0038025)
12.7 76.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
12.6 50.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
11.9 35.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
11.7 35.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
11.0 54.8 GO:0032184 SUMO polymer binding(GO:0032184)
10.6 63.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
9.4 75.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
9.3 37.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
9.0 251.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
8.4 50.2 GO:0033142 progesterone receptor binding(GO:0033142)
7.8 38.9 GO:0017002 activin-activated receptor activity(GO:0017002)
7.6 22.7 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
7.3 29.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
7.1 35.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
6.9 62.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
6.8 87.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
6.7 20.0 GO:0038191 neuropilin binding(GO:0038191)
6.7 20.0 GO:0004994 somatostatin receptor activity(GO:0004994)
6.6 92.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
6.6 39.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
6.6 32.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
6.5 26.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
6.5 26.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
6.4 19.3 GO:0050827 toxin receptor binding(GO:0050827)
6.3 88.2 GO:0017154 semaphorin receptor activity(GO:0017154)
6.1 18.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
6.1 30.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
5.9 17.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
5.9 35.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
5.9 105.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
5.8 52.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
5.8 46.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
5.7 11.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
5.6 33.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
5.4 75.0 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
5.3 37.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
5.3 15.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
5.1 20.6 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
5.1 15.3 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
5.1 25.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
4.8 14.3 GO:0015217 ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
4.7 14.2 GO:0001847 opsonin receptor activity(GO:0001847)
4.7 84.6 GO:0034185 apolipoprotein binding(GO:0034185)
4.7 65.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
4.7 18.7 GO:0035174 histone serine kinase activity(GO:0035174)
4.6 13.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
4.6 111.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
4.6 18.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
4.5 18.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
4.5 13.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.4 80.1 GO:0004890 GABA-A receptor activity(GO:0004890)
4.4 13.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
4.4 22.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
4.4 104.9 GO:0017075 syntaxin-1 binding(GO:0017075)
4.3 39.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
4.3 17.0 GO:0070699 type II activin receptor binding(GO:0070699)
4.2 16.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
4.2 100.7 GO:0043274 phospholipase binding(GO:0043274)
4.1 28.8 GO:0008046 axon guidance receptor activity(GO:0008046)
4.1 24.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
4.1 32.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
4.0 8.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
4.0 16.1 GO:0036033 mediator complex binding(GO:0036033)
4.0 24.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
4.0 32.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
4.0 15.9 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
3.9 15.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
3.9 19.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
3.8 11.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
3.8 15.3 GO:0005131 growth hormone receptor binding(GO:0005131)
3.7 14.9 GO:0033691 sialic acid binding(GO:0033691)
3.7 22.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.6 3.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
3.5 10.6 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
3.5 28.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
3.5 52.2 GO:0050321 tau-protein kinase activity(GO:0050321)
3.4 158.3 GO:0045296 cadherin binding(GO:0045296)
3.4 3.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
3.4 10.2 GO:0031208 POZ domain binding(GO:0031208)
3.4 23.8 GO:0034711 inhibin binding(GO:0034711)
3.4 16.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
3.4 50.6 GO:0050811 GABA receptor binding(GO:0050811)
3.3 16.5 GO:0004359 glutaminase activity(GO:0004359)
3.2 6.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
3.2 12.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.2 66.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
3.1 18.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.1 21.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
3.1 27.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
3.0 3.0 GO:0034437 glycoprotein transporter activity(GO:0034437)
3.0 29.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
3.0 14.9 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
3.0 17.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
2.9 14.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.9 14.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
2.9 129.4 GO:0045499 chemorepellent activity(GO:0045499)
2.8 17.0 GO:0032051 clathrin light chain binding(GO:0032051)
2.8 19.8 GO:0001618 virus receptor activity(GO:0001618)
2.8 53.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
2.8 14.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.8 11.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
2.8 13.8 GO:0045503 dynein light chain binding(GO:0045503)
2.7 2.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
2.7 8.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
2.7 34.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
2.6 5.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
2.6 13.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.6 7.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
2.5 5.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.5 95.6 GO:0001540 beta-amyloid binding(GO:0001540)
2.5 25.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
2.5 12.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
2.5 29.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
2.5 17.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
2.4 9.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
2.3 18.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.3 16.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.3 14.0 GO:0004016 adenylate cyclase activity(GO:0004016)
2.3 44.2 GO:0051018 protein kinase A binding(GO:0051018)
2.3 16.2 GO:0035184 histone threonine kinase activity(GO:0035184)
2.3 13.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.3 52.8 GO:0031489 myosin V binding(GO:0031489)
2.3 16.0 GO:0061665 SUMO ligase activity(GO:0061665)
2.3 6.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
2.3 2.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.2 8.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.2 8.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.2 19.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
2.2 24.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.2 19.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.2 6.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
2.1 73.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.1 66.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
2.1 29.3 GO:0051010 microtubule plus-end binding(GO:0051010)
2.1 12.5 GO:0070728 leucine binding(GO:0070728)
2.1 6.2 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
2.1 12.4 GO:0042296 ISG15 transferase activity(GO:0042296)
2.0 2.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
2.0 10.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.0 12.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.0 6.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.0 6.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
2.0 4.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.0 17.8 GO:0051011 microtubule minus-end binding(GO:0051011)
2.0 23.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.9 21.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.9 11.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.9 5.8 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
1.9 5.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.9 7.5 GO:0097109 neuroligin family protein binding(GO:0097109)
1.9 25.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
1.8 5.5 GO:0019002 GMP binding(GO:0019002)
1.8 5.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.8 9.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.8 62.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
1.8 8.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.8 40.3 GO:0001786 phosphatidylserine binding(GO:0001786)
1.7 13.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
1.7 36.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.7 8.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.7 47.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.7 1.7 GO:0070538 oleic acid binding(GO:0070538)
1.7 5.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
1.6 115.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.6 23.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
1.6 13.2 GO:0001784 phosphotyrosine binding(GO:0001784)
1.6 21.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
1.6 16.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.6 27.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
1.6 4.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.6 4.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.6 4.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.6 6.2 GO:0008061 chitin binding(GO:0008061)
1.5 7.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
1.5 55.6 GO:0050699 WW domain binding(GO:0050699)
1.5 4.6 GO:0097322 7SK snRNA binding(GO:0097322)
1.5 4.6 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.5 1.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.5 3.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.5 3.0 GO:0097016 L27 domain binding(GO:0097016)
1.5 9.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.5 7.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.5 4.5 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
1.5 3.0 GO:0051425 PTB domain binding(GO:0051425)
1.5 10.5 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
1.5 5.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.4 7.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.4 5.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.4 4.2 GO:0034041 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
1.4 58.1 GO:0030507 spectrin binding(GO:0030507)
1.4 9.6 GO:0015616 DNA translocase activity(GO:0015616)
1.4 5.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.4 2.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.4 15.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
1.4 16.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.3 4.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.3 2.7 GO:0070840 dynein complex binding(GO:0070840)
1.3 13.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.3 39.2 GO:0017091 AU-rich element binding(GO:0017091)
1.3 374.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.3 13.0 GO:0042043 neurexin family protein binding(GO:0042043)
1.3 102.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.3 5.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.3 20.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.3 205.5 GO:0003714 transcription corepressor activity(GO:0003714)
1.3 1.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
1.3 5.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
1.2 8.7 GO:0015248 sterol transporter activity(GO:0015248)
1.2 3.7 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
1.2 12.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
1.2 27.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.2 6.1 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
1.2 3.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
1.2 14.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.2 6.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.2 3.6 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
1.2 8.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.2 4.6 GO:2001069 glycogen binding(GO:2001069)
1.2 8.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.2 26.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.1 9.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.1 2.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
1.1 4.5 GO:0016149 translation release factor activity, codon specific(GO:0016149)
1.1 27.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.1 5.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
1.1 121.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
1.1 11.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.1 24.0 GO:0015085 calcium ion transmembrane transporter activity(GO:0015085)
1.1 3.3 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
1.1 3.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.1 20.4 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
1.1 107.6 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
1.1 3.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
1.0 7.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
1.0 54.6 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
1.0 16.3 GO:0017048 Rho GTPase binding(GO:0017048)
1.0 3.0 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
1.0 35.0 GO:0005484 SNAP receptor activity(GO:0005484)
1.0 61.7 GO:0048365 Rac GTPase binding(GO:0048365)
1.0 36.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.0 85.1 GO:0016247 channel regulator activity(GO:0016247)
1.0 59.6 GO:0003777 microtubule motor activity(GO:0003777)
1.0 1.0 GO:0019172 glyoxalase III activity(GO:0019172)
0.9 5.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.9 5.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.9 2.8 GO:0098809 nitrite reductase activity(GO:0098809)
0.9 1.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 13.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.9 10.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.9 9.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.9 3.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.9 4.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.9 37.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.9 31.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.8 84.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8 24.5 GO:0019894 kinesin binding(GO:0019894)
0.8 8.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 22.4 GO:0070412 R-SMAD binding(GO:0070412)
0.8 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.8 5.0 GO:0005042 netrin receptor activity(GO:0005042)
0.8 2.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.8 2.5 GO:0071253 connexin binding(GO:0071253)
0.8 17.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 12.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.8 4.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 9.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.8 4.0 GO:0034235 GPI anchor binding(GO:0034235)
0.8 1.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.8 3.9 GO:0048495 Roundabout binding(GO:0048495)
0.8 2.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 10.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.8 2.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.8 2.3 GO:1990405 protein antigen binding(GO:1990405)
0.8 4.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.8 3.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.8 0.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.8 0.8 GO:0048156 tau protein binding(GO:0048156)
0.7 5.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.7 5.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.7 11.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.7 11.8 GO:0022839 ion gated channel activity(GO:0022839)
0.7 145.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.7 4.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7 2.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.7 76.9 GO:0017124 SH3 domain binding(GO:0017124)
0.7 15.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.7 11.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.7 13.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.7 0.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.7 2.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 1.9 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.6 12.7 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.6 3.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.6 4.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.6 21.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 4.9 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.6 6.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.6 6.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.6 6.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 3.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.6 1.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.6 7.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.6 78.7 GO:0008017 microtubule binding(GO:0008017)
0.6 1.8 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.6 8.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 13.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.6 1.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.6 137.1 GO:0005096 GTPase activator activity(GO:0005096)
0.6 2.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.6 8.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 5.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 4.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.5 1.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 4.8 GO:0030275 LRR domain binding(GO:0030275)
0.5 7.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 2.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 1.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.5 7.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.5 9.2 GO:0005267 potassium channel activity(GO:0005267)
0.5 1.5 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.5 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.5 2.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5 3.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.5 1.5 GO:0042895 antibiotic transporter activity(GO:0042895)
0.5 2.0 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.5 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.5 1.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.5 2.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.5 1.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.5 2.8 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.5 11.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.5 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 1.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 6.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 5.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 3.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.4 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 10.9 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.4 6.5 GO:0031402 sodium ion binding(GO:0031402)
0.4 4.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 3.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 11.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 4.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 91.9 GO:0005543 phospholipid binding(GO:0005543)
0.4 1.7 GO:0070290 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 22.6 GO:0030674 protein binding, bridging(GO:0030674)
0.4 3.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 1.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 6.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.4 2.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.4 2.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 21.8 GO:0002020 protease binding(GO:0002020)
0.4 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 1.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 9.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 1.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 5.4 GO:0051787 misfolded protein binding(GO:0051787)
0.3 2.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 0.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 0.7 GO:0089720 caspase binding(GO:0089720)
0.3 0.7 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.3 1.0 GO:0016775 phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.3 1.9 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 4.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 1.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 0.6 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.3 1.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 2.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 4.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 28.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.3 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.3 1.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 1.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 1.8 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.2 1.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 4.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 0.5 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.2 1.0 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 0.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 3.0 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.2 3.4 GO:0030276 clathrin binding(GO:0030276)
0.2 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 2.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.9 GO:0004075 biotin carboxylase activity(GO:0004075)
0.2 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 0.8 GO:0008066 glutamate receptor activity(GO:0008066)
0.2 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.2 4.2 GO:0005521 lamin binding(GO:0005521)
0.2 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 0.6 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.2 0.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.2 0.8 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 1.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.7 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.6 GO:0008443 phosphofructokinase activity(GO:0008443)
0.2 0.5 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.2 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.0 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 4.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 0.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 2.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 10.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.7 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.1 1.3 GO:0034943 acyl-CoA ligase activity(GO:0003996) succinate-CoA ligase activity(GO:0004774) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 14.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 0.5 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.2 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 7.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 5.5 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.1 3.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 2.3 GO:0051117 ATPase binding(GO:0051117)
0.1 0.3 GO:0070878 primary miRNA binding(GO:0070878)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 1.5 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)