Motif ID: Chd1_Pml

Z-value: 4.823

Transcription factors associated with Chd1_Pml:

Gene SymbolEntrez IDGene Name
Chd1 ENSMUSG00000023852.7 Chd1
Pml ENSMUSG00000036986.10 Pml

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pmlmm10_v2_chr9_-_58249660_58249672-0.201.2e-01Click!
Chd1mm10_v2_chr17_+_15704963_157049940.114.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Chd1_Pml

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800024 144.665 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr8_-_84800344 114.172 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr15_-_66286224 99.528 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chrX_+_170009659 83.779 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr6_+_99692679 81.221 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr4_-_120287349 77.677 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr2_+_155775333 64.345 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chr6_-_32588192 61.577 ENSMUST00000115096.2
Plxna4
plexin A4
chr6_-_114042020 52.846 ENSMUST00000101045.3
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr11_-_6065737 51.998 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr16_-_67620880 51.635 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr4_+_124657646 50.811 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr12_-_4477138 50.486 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr1_-_56972437 49.571 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr15_-_12321899 48.356 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chrX_+_170009892 48.005 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr10_-_43174521 45.465 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr11_-_6065538 45.197 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr4_+_97777780 45.163 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr6_+_54816906 44.959 ENSMUST00000079869.6
Znrf2
zinc and ring finger 2

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 876 entries
Log-likelihood per target Total log-likelihoodTermDescription
22.4 314.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
10.8 172.0 GO:0060081 membrane hyperpolarization(GO:0060081)
1.1 159.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
9.8 157.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
5.1 148.8 GO:0060074 synapse maturation(GO:0060074)
6.1 139.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
3.6 138.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
6.7 114.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1 111.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
33.9 101.7 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
2.0 99.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
8.1 96.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
30.5 91.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
12.6 88.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
29.1 87.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
2.9 77.7 GO:2001222 regulation of neuron migration(GO:2001222)
18.8 75.4 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
2.0 74.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
3.7 73.8 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
7.9 71.3 GO:0033602 negative regulation of dopamine secretion(GO:0033602)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 277 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 625.9 GO:0016021 integral component of membrane(GO:0016021)
2.0 394.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 256.6 GO:0005768 endosome(GO:0005768)
6.0 214.6 GO:0032809 neuronal cell body membrane(GO:0032809)
6.8 205.5 GO:0043194 axon initial segment(GO:0043194)
5.6 202.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.6 198.7 GO:0070382 exocytic vesicle(GO:0070382)
1.6 197.5 GO:0031225 anchored component of membrane(GO:0031225)
3.0 182.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
2.1 173.7 GO:0043195 terminal bouton(GO:0043195)
4.5 162.2 GO:0048786 presynaptic active zone(GO:0048786)
2.2 161.3 GO:0043198 dendritic shaft(GO:0043198)
2.3 146.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.4 140.7 GO:0055037 recycling endosome(GO:0055037)
0.9 119.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.6 116.8 GO:0043204 perikaryon(GO:0043204)
3.7 114.2 GO:0051233 spindle midzone(GO:0051233)
4.2 112.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
11.1 110.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.8 106.4 GO:0030427 site of polarized growth(GO:0030427)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 469 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 374.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
9.0 251.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.3 205.5 GO:0003714 transcription corepressor activity(GO:0003714)
3.4 158.3 GO:0045296 cadherin binding(GO:0045296)
0.7 145.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.6 137.1 GO:0005096 GTPase activator activity(GO:0005096)
2.9 129.4 GO:0045499 chemorepellent activity(GO:0045499)
1.1 121.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
1.6 115.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
4.6 111.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.1 107.6 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
5.9 105.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
4.4 104.9 GO:0017075 syntaxin-1 binding(GO:0017075)
1.3 102.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
4.2 100.7 GO:0043274 phospholipase binding(GO:0043274)
2.5 95.6 GO:0001540 beta-amyloid binding(GO:0001540)
6.6 92.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 91.9 GO:0005543 phospholipid binding(GO:0005543)
6.3 88.2 GO:0017154 semaphorin receptor activity(GO:0017154)
6.8 87.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)