Motif ID: Chd1_Pml
Z-value: 4.823


Transcription factors associated with Chd1_Pml:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Chd1 | ENSMUSG00000023852.7 | Chd1 |
Pml | ENSMUSG00000036986.10 | Pml |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pml | mm10_v2_chr9_-_58249660_58249672 | -0.20 | 1.2e-01 | Click! |
Chd1 | mm10_v2_chr17_+_15704963_15704994 | 0.11 | 4.1e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 876 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
22.4 | 314.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
10.8 | 172.0 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
1.1 | 159.4 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
9.8 | 157.5 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
5.1 | 148.8 | GO:0060074 | synapse maturation(GO:0060074) |
6.1 | 139.6 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
3.6 | 138.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
6.7 | 114.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
1.1 | 111.1 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
33.9 | 101.7 | GO:0060466 | activation of meiosis involved in egg activation(GO:0060466) |
2.0 | 99.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
8.1 | 96.7 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
30.5 | 91.6 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
12.6 | 88.2 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
29.1 | 87.4 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) |
2.9 | 77.7 | GO:2001222 | regulation of neuron migration(GO:2001222) |
18.8 | 75.4 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
2.0 | 74.1 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
3.7 | 73.8 | GO:2000463 | positive regulation of excitatory postsynaptic potential(GO:2000463) |
7.9 | 71.3 | GO:0033602 | negative regulation of dopamine secretion(GO:0033602) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 277 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 625.9 | GO:0016021 | integral component of membrane(GO:0016021) |
2.0 | 394.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.6 | 256.6 | GO:0005768 | endosome(GO:0005768) |
6.0 | 214.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
6.8 | 205.5 | GO:0043194 | axon initial segment(GO:0043194) |
5.6 | 202.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
1.6 | 198.7 | GO:0070382 | exocytic vesicle(GO:0070382) |
1.6 | 197.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
3.0 | 182.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
2.1 | 173.7 | GO:0043195 | terminal bouton(GO:0043195) |
4.5 | 162.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
2.2 | 161.3 | GO:0043198 | dendritic shaft(GO:0043198) |
2.3 | 146.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
1.4 | 140.7 | GO:0055037 | recycling endosome(GO:0055037) |
0.9 | 119.8 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
1.6 | 116.8 | GO:0043204 | perikaryon(GO:0043204) |
3.7 | 114.2 | GO:0051233 | spindle midzone(GO:0051233) |
4.2 | 112.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
11.1 | 110.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.8 | 106.4 | GO:0030427 | site of polarized growth(GO:0030427) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 469 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 374.8 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
9.0 | 251.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
1.3 | 205.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
3.4 | 158.3 | GO:0045296 | cadherin binding(GO:0045296) |
0.7 | 145.2 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.6 | 137.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
2.9 | 129.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
1.1 | 121.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
1.6 | 115.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
4.6 | 111.0 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
1.1 | 107.6 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
5.9 | 105.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
4.4 | 104.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
1.3 | 102.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
4.2 | 100.7 | GO:0043274 | phospholipase binding(GO:0043274) |
2.5 | 95.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
6.6 | 92.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.4 | 91.9 | GO:0005543 | phospholipid binding(GO:0005543) |
6.3 | 88.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
6.8 | 87.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |