Motif ID: Creb1

Z-value: 2.030


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.302.1e-02Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_56535047 15.087 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr7_-_38107490 12.707 ENSMUST00000108023.3
 Ccne1
cyclin E1
chr7_-_137314394 12.448 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr15_-_76710486 11.977 ENSMUST00000036852.7
 Recql4
RecQ protein-like 4
chr19_+_6084983 11.165 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr11_+_43528759 9.653 ENSMUST00000050574.6
 Ccnjl
cyclin J-like
chr10_+_121033960 9.620 ENSMUST00000020439.4
ENSMUST00000175867.1
 Wif1

Wnt inhibitory factor 1

chr14_-_31251194 8.804 ENSMUST00000022459.3
 Phf7
PHD finger protein 7
chr13_-_29984219 8.567 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr10_-_30200492 8.101 ENSMUST00000099985.4
 Cenpw
centromere protein W
chr7_-_30664986 7.768 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr10_+_127041931 7.330 ENSMUST00000006915.7
ENSMUST00000120542.1
 Mettl1

methyltransferase like 1

chr12_+_52097737 7.126 ENSMUST00000040090.9
 Nubpl
nucleotide binding protein-like
chr2_+_156840966 6.912 ENSMUST00000109564.1
 Tgif2
TGFB-induced factor homeobox 2
chr11_-_106160101 6.835 ENSMUST00000045923.3
 Limd2
LIM domain containing 2
chr17_+_46646225 6.818 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
 Mrpl2


mitochondrial ribosomal protein L2


chr4_+_107879745 6.717 ENSMUST00000030348.5
 Magoh
mago-nashi homolog, proliferation-associated (Drosophila)
chr7_+_3629985 6.609 ENSMUST00000008517.6
ENSMUST00000179769.1
 Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr14_+_63860290 6.308 ENSMUST00000022528.4
 Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr9_-_96478660 6.150 ENSMUST00000057500.4
 Rnf7
ring finger protein 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 172 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 16.7 GO:0006270 DNA replication initiation(GO:0006270)
0.6 15.5 GO:0030488 tRNA methylation(GO:0030488)
5.0 15.1 GO:0021759 globus pallidus development(GO:0021759)
1.3 15.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
3.6 14.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 13.5 GO:0006364 rRNA processing(GO:0006364)
0.1 12.5 GO:0007018 microtubule-based movement(GO:0007018)
2.4 12.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
3.7 11.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.9 11.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.9 10.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 10.7 GO:0098792 xenophagy(GO:0098792)
0.9 9.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 9.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
3.1 9.3 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.6 9.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 9.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
2.2 8.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.2 8.7 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 8.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 36.1 GO:0005730 nucleolus(GO:0005730)
0.1 30.1 GO:0005667 transcription factor complex(GO:0005667)
0.2 17.4 GO:0000776 kinetochore(GO:0000776)
0.3 17.0 GO:0005871 kinesin complex(GO:0005871)
1.1 16.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 14.0 GO:0005694 chromosome(GO:0005694)
0.3 13.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 13.0 GO:0043198 dendritic shaft(GO:0043198)
0.2 12.6 GO:0005643 nuclear pore(GO:0005643)
0.8 12.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 11.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
3.7 11.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.2 11.2 GO:0008278 cohesin complex(GO:0008278)
0.1 10.4 GO:0000793 condensed chromosome(GO:0000793)
1.7 10.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 9.7 GO:0001650 fibrillar center(GO:0001650)
1.4 8.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 8.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 8.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.3 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 40.1 GO:0044822 poly(A) RNA binding(GO:0044822)
0.4 31.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 18.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 18.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 17.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 16.6 GO:0003677 DNA binding(GO:0003677)
1.3 15.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.8 15.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.4 14.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 12.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3 12.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
2.4 12.0 GO:0000405 bubble DNA binding(GO:0000405)
1.6 11.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.9 10.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 9.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 9.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.3 9.3 GO:0017091 AU-rich element binding(GO:0017091)
1.5 8.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.4 8.5 GO:0017160 Ral GTPase binding(GO:0017160)
2.8 8.3 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)