Motif ID: Crem_Jdp2

Z-value: 0.501

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Jdp2mm10_v2_chr12_+_85599047_855991050.496.8e-05Click!
Cremmm10_v2_chr18_-_3337539_33376000.331.1e-02Click!


Activity profile for motif Crem_Jdp2.

activity profile for motif Crem_Jdp2


Sorted Z-values histogram for motif Crem_Jdp2

Sorted Z-values for motif Crem_Jdp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_45885479 4.372 ENSMUST00000034053.5
 Pdlim3
PDZ and LIM domain 3
chr15_-_12321899 4.062 ENSMUST00000180521.1
 1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr7_+_112679327 2.917 ENSMUST00000106638.2
 Tead1
TEA domain family member 1
chr7_+_112679314 2.817 ENSMUST00000084705.5
ENSMUST00000059768.10
 Tead1

TEA domain family member 1

chrX_+_66653003 2.736 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr5_-_124032214 2.568 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr7_+_79500018 2.350 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr13_+_19623163 2.215 ENSMUST00000002883.5
 Sfrp4
secreted frizzled-related protein 4
chr15_+_34238026 2.161 ENSMUST00000022867.3
 Laptm4b
lysosomal-associated protein transmembrane 4B
chr9_-_52679429 2.081 ENSMUST00000098768.2
 AI593442
expressed sequence AI593442
chr6_+_112273758 2.059 ENSMUST00000032376.5
 Lmcd1
LIM and cysteine-rich domains 1
chr11_-_88718223 1.891 ENSMUST00000107909.1
 Msi2
musashi RNA-binding protein 2
chr2_+_109280738 1.889 ENSMUST00000028527.7
 Kif18a
kinesin family member 18A
chr7_+_79500081 1.886 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr1_+_135729147 1.651 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr1_+_95313607 1.650 ENSMUST00000059975.6
 Fam174a
family with sequence similarity 174, member A
chr9_-_20976762 1.545 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr19_+_59260878 1.543 ENSMUST00000026084.3
 Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr1_+_184034381 1.466 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chrX_+_166238901 1.465 ENSMUST00000112235.1
 Gpm6b
glycoprotein m6b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.7 5.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.0 3.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.4 2.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 2.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.7 2.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 2.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 2.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 2.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 2.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 2.0 GO:0048864 stem cell development(GO:0048864)
0.4 1.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.1 1.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 1.7 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.7 GO:0070527 platelet aggregation(GO:0070527)
0.3 1.6 GO:0021764 amygdala development(GO:0021764)
0.0 1.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.5 1.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 1.5 GO:0048388 endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.3 GO:0030018 Z disc(GO:0030018)
0.3 3.0 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.7 GO:0031045 dense core granule(GO:0031045)
0.2 2.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 1.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 1.9 GO:0005844 polysome(GO:0005844)
0.0 1.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.5 GO:0042581 specific granule(GO:0042581)
0.2 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 0.8 GO:1990423 RZZ complex(GO:1990423)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.5 6.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.3 4.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 2.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 2.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 2.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 2.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.0 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 1.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 1.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 1.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 1.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)