Motif ID: Crx_Gsc

Z-value: 0.459

Transcription factors associated with Crx_Gsc:

Gene SymbolEntrez IDGene Name
Crx ENSMUSG00000041578.9 Crx
Gsc ENSMUSG00000021095.4 Gsc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Crxmm10_v2_chr7_-_15879844_158799680.246.9e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crx_Gsc

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_104231390 5.052 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr9_-_53975246 4.131 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chrX_+_7919816 3.064 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr4_+_74013442 2.727 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr7_+_44384098 2.726 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3

synaptotagmin III

chr14_-_19977249 2.630 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr7_+_44384803 2.628 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr14_+_65968483 2.516 ENSMUST00000022616.6
Clu
clusterin
chr7_+_44384604 2.492 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chrY_+_1010543 2.244 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr8_-_54724317 2.121 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr16_+_23290464 1.877 ENSMUST00000115335.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr1_-_154725920 1.866 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr14_-_19977040 1.819 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977151 1.795 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr15_+_82252397 1.744 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr2_+_69722797 1.653 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr2_+_65845767 1.581 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_-_24763047 1.572 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr4_-_140246751 1.563 ENSMUST00000039331.8
Igsf21
immunoglobulin superfamily, member 21

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 5.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 3.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 3.1 GO:0002021 response to dietary excess(GO:0002021)
0.2 2.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 2.6 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.4 2.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.2 2.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 2.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 2.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 1.9 GO:1990743 protein sialylation(GO:1990743)
0.4 1.9 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 1.6 GO:0033574 response to testosterone(GO:0033574)
0.4 1.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 1.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 1.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.5 GO:0019835 cytolysis(GO:0019835)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0070382 exocytic vesicle(GO:0070382)
0.5 5.1 GO:0045298 tubulin complex(GO:0045298)
0.1 4.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.6 GO:0005814 centriole(GO:0005814)
0.1 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.4 2.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 2.1 GO:0031143 pseudopodium(GO:0031143)
0.2 1.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.3 1.1 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 5.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 5.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.2 3.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 2.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.5 GO:0042393 histone binding(GO:0042393)
0.0 2.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 2.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 2.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.2 1.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)