Motif ID: Ctcfl_Ctcf

Z-value: 1.268

Transcription factors associated with Ctcfl_Ctcf:

Gene SymbolEntrez IDGene Name
Ctcf ENSMUSG00000005698.9 Ctcf
Ctcfl ENSMUSG00000070495.5 Ctcfl

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ctcflmm10_v2_chr2_-_173119402_173119525-0.264.5e-02Click!
Ctcfmm10_v2_chr8_+_105636509_105636589-0.201.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ctcfl_Ctcf

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_137741601 14.194 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr5_-_137741102 13.356 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr3_-_89160155 11.074 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr5_+_135806859 10.793 ENSMUST00000126232.1
Srrm3
serine/arginine repetitive matrix 3
chr2_+_65620829 10.720 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_+_157914618 10.450 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr11_+_116918844 10.404 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr9_+_34486125 10.378 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr18_+_36952621 10.265 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr18_-_43393346 10.256 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr2_-_32353283 9.200 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1

dynamin 1

chr8_-_84937347 9.167 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr17_-_25433775 9.088 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr19_+_6418731 9.033 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr5_-_123132651 8.754 ENSMUST00000031401.5
Rhof
ras homolog gene family, member f
chr4_+_43381979 8.706 ENSMUST00000035645.5
ENSMUST00000144911.1
Rusc2

RUN and SH3 domain containing 2

chr2_-_32353247 8.628 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr2_+_154613297 8.419 ENSMUST00000081926.6
ENSMUST00000109702.1
Zfp341

zinc finger protein 341

chr7_+_16310412 8.193 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr6_-_136173492 8.068 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 203 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 34.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.3 18.1 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.2 15.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
3.7 14.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 14.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 14.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 12.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
2.4 11.9 GO:0046684 response to pyrethroid(GO:0046684)
0.3 10.8 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
2.7 10.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
2.1 10.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.7 10.3 GO:0051764 actin crosslink formation(GO:0051764)
3.0 9.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
1.3 9.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 9.0 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.5 8.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049) detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.9 7.6 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 7.6 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
2.5 7.5 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 7.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 30.7 GO:0045298 tubulin complex(GO:0045298)
1.8 29.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 26.9 GO:0070382 exocytic vesicle(GO:0070382)
0.3 25.9 GO:0043198 dendritic shaft(GO:0043198)
1.4 20.4 GO:0043196 varicosity(GO:0043196)
0.1 16.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 14.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 11.2 GO:0045211 postsynaptic membrane(GO:0045211)
2.2 11.1 GO:0044316 cone cell pedicle(GO:0044316)
0.2 9.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.2 9.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.7 8.1 GO:0043083 synaptic cleft(GO:0043083)
0.5 7.4 GO:0031512 motile primary cilium(GO:0031512)
0.2 7.4 GO:0042734 presynaptic membrane(GO:0042734)
0.2 6.8 GO:0060077 inhibitory synapse(GO:0060077)
0.7 6.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 6.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 6.2 GO:0032039 integrator complex(GO:0032039)
0.0 6.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 5.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 30.7 GO:0034185 apolipoprotein binding(GO:0034185)
1.5 29.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
2.6 25.9 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 18.6 GO:0001540 beta-amyloid binding(GO:0001540)
3.7 18.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 13.6 GO:0051117 ATPase binding(GO:0051117)
0.2 11.8 GO:0019894 kinesin binding(GO:0019894)
2.1 10.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.6 10.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
2.3 9.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 8.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 7.8 GO:0005246 calcium channel regulator activity(GO:0005246)
2.5 7.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 7.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.3 7.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.9 6.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 6.8 GO:0000287 magnesium ion binding(GO:0000287)
0.1 6.5 GO:0005496 steroid binding(GO:0005496)
2.1 6.2 GO:0032450 oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
1.0 6.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)