Motif ID: Ddit3

Z-value: 0.991


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.411.5e-03Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_109823585 12.021 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr5_+_137553517 10.533 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr19_-_59076069 8.776 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr11_-_35798884 8.348 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr9_-_121495678 7.437 ENSMUST00000035120.4
Cck
cholecystokinin
chr15_-_66948419 7.287 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr6_+_21215472 6.656 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr10_+_112271123 6.495 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chrX_+_166238901 6.444 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chrX_+_103422010 6.260 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr3_+_9403049 5.065 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
C030034L19Rik


RIKEN cDNA C030034L19 gene


chr15_-_43869993 4.918 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr8_-_99416397 4.899 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
Cdh8




cadherin 8




chr1_-_5019342 4.839 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr14_-_103843685 4.765 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr18_+_37307445 4.491 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr7_-_126082406 4.430 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr7_+_126776939 4.241 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr15_-_59082026 4.168 ENSMUST00000080371.6
Mtss1
metastasis suppressor 1
chr18_+_37421418 4.138 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr14_+_65971164 4.135 ENSMUST00000144619.1
Clu
clusterin
chr6_+_115675983 4.081 ENSMUST00000068960.9
D830050J10Rik
RIKEN cDNA D830050J10 gene
chr2_+_181837854 3.935 ENSMUST00000029116.7
ENSMUST00000108754.1
Pcmtd2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr1_-_126492900 3.862 ENSMUST00000161954.1
Nckap5
NCK-associated protein 5
chr3_-_127409014 3.813 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr18_+_37333853 3.801 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr15_+_32244801 3.769 ENSMUST00000067458.6
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_+_90537306 3.692 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr14_+_65970804 3.609 ENSMUST00000138191.1
Clu
clusterin
chr14_+_65971049 3.602 ENSMUST00000128539.1
Clu
clusterin
chr6_+_86078070 3.567 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr2_-_120850598 3.560 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr3_-_127409044 3.554 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr2_-_45117349 3.528 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr8_+_12915879 3.438 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr9_-_44799179 3.408 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr14_-_66868572 3.359 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chr3_-_127408937 3.351 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr3_-_127408986 3.317 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr3_+_90537242 3.313 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chrX_-_162565514 3.290 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr13_+_42680565 3.253 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr4_+_103619580 3.240 ENSMUST00000106827.1
Dab1
disabled 1
chr5_+_3343893 3.197 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr1_-_126492683 3.169 ENSMUST00000162877.1
Nckap5
NCK-associated protein 5
chr18_+_37355271 3.113 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr7_+_24112314 2.890 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chrX_-_37104523 2.860 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr1_-_58586191 2.757 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr2_-_130839683 2.741 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr4_+_101550411 2.638 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr16_-_87432597 2.598 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr5_+_137288273 2.519 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr7_+_120677579 2.463 ENSMUST00000060175.6
BC030336
cDNA sequence BC030336
chr1_+_165461037 2.438 ENSMUST00000027853.5
Mpc2
mitochondrial pyruvate carrier 2
chr2_+_119351222 2.371 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr2_+_23069210 2.345 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr5_-_36695969 2.196 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr2_-_126876117 2.164 ENSMUST00000028843.5
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr5_-_131538687 2.128 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr13_+_24614608 2.099 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr11_-_116199040 2.063 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr17_-_46890405 2.062 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr12_+_10390756 2.043 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr16_-_60605226 2.009 ENSMUST00000068860.6
Epha6
Eph receptor A6
chr1_+_34121250 1.886 ENSMUST00000183006.1
Dst
dystonin
chr16_-_45724600 1.850 ENSMUST00000096057.4
Tagln3
transgelin 3
chr3_-_92083132 1.814 ENSMUST00000058150.6
Lor
loricrin
chr5_-_114273702 1.794 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr2_-_131328982 1.792 ENSMUST00000110194.1
Rnf24
ring finger protein 24
chr1_+_174501796 1.784 ENSMUST00000030039.7
Fmn2
formin 2
chr2_-_32961592 1.783 ENSMUST00000133832.1
ENSMUST00000124492.1
ENSMUST00000145578.1
ENSMUST00000127321.1
ENSMUST00000113200.1
Lrsam1




leucine rich repeat and sterile alpha motif containing 1




chr1_-_165460430 1.768 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr9_-_20644726 1.735 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
Fbxl12




F-box and leucine-rich repeat protein 12




chr5_-_74531619 1.732 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2



Sec1 family domain containing 2



chr16_+_78301458 1.682 ENSMUST00000023572.7
Cxadr
coxsackie virus and adenovirus receptor
chr6_+_125494419 1.655 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr14_+_63606491 1.582 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chr16_+_24721842 1.566 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr3_+_108186332 1.551 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr11_+_60728398 1.520 ENSMUST00000018743.4
Mief2
mitochondrial elongation factor 2
chr1_-_39651165 1.519 ENSMUST00000053355.4
Creg2
cellular repressor of E1A-stimulated genes 2
chr16_+_36041184 1.517 ENSMUST00000042203.8
Wdr5b
WD repeat domain 5B
chr18_+_38993126 1.484 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr10_+_79996479 1.438 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_-_79296906 1.421 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr15_-_83510793 1.358 ENSMUST00000154401.1
Ttll1
tubulin tyrosine ligase-like 1
chr7_+_64287665 1.343 ENSMUST00000032736.4
Mtmr10
myotubularin related protein 10
chr9_-_45906369 1.333 ENSMUST00000161187.1
Rnf214
ring finger protein 214
chr8_-_64693027 1.329 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr15_-_93595877 1.296 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr7_-_31150981 1.295 ENSMUST00000085636.6
ENSMUST00000001280.7
Gramd1a

GRAM domain containing 1A

chr14_+_66868850 1.260 ENSMUST00000100453.1
Gm5464
predicted gene 5464
chr9_-_95845215 1.223 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr16_-_15594507 1.219 ENSMUST00000115776.1
ENSMUST00000115777.3
Ube2v2

ubiquitin-conjugating enzyme E2 variant 2

chr12_-_69681795 1.214 ENSMUST00000183277.1
ENSMUST00000035773.7
Sos2

son of sevenless homolog 2 (Drosophila)

chr11_-_61930197 1.153 ENSMUST00000108710.1
Akap10
A kinase (PRKA) anchor protein 10
chr11_+_54303798 1.090 ENSMUST00000093106.5
Acsl6
acyl-CoA synthetase long-chain family member 6
chr15_-_83510861 1.077 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
Ttll1


tubulin tyrosine ligase-like 1


chr1_+_87326997 1.000 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr11_+_70214105 0.969 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr8_-_67818284 0.912 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr8_+_94386438 0.911 ENSMUST00000161576.1
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_-_53657339 0.900 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr7_+_18884679 0.877 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr6_+_71322775 0.859 ENSMUST00000065248.7
Cd8b1
CD8 antigen, beta chain 1
chr16_+_96145391 0.844 ENSMUST00000023913.8
ENSMUST00000135448.1
Wrb

tryptophan rich basic protein

chr6_+_38534823 0.755 ENSMUST00000019833.4
1110001J03Rik
RIKEN cDNA 1110001J03 gene
chrX_-_57338598 0.711 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr1_+_87327008 0.707 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr5_-_129887442 0.697 ENSMUST00000094280.3
Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr5_-_31526693 0.679 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr6_+_88724667 0.662 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr2_-_164071089 0.629 ENSMUST00000018466.3
Tomm34
translocase of outer mitochondrial membrane 34
chr16_-_4939579 0.612 ENSMUST00000181498.1
Gm16861
predicted gene, 16861
chr7_+_84528964 0.601 ENSMUST00000180387.1
Gm2115
predicted gene 2115
chr18_+_42275353 0.590 ENSMUST00000046972.7
ENSMUST00000091920.5
Rbm27

RNA binding motif protein 27

chr11_+_110997487 0.589 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_-_35495487 0.569 ENSMUST00000033927.6
Eri1
exoribonuclease 1
chr5_+_31526989 0.567 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr2_-_164071124 0.543 ENSMUST00000109384.3
Tomm34
translocase of outer mitochondrial membrane 34
chr13_-_104816908 0.521 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr11_+_116198853 0.463 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr8_-_47533439 0.442 ENSMUST00000039061.8
Trappc11
trafficking protein particle complex 11
chr14_-_47568427 0.438 ENSMUST00000042988.6
Atg14
autophagy related 14
chr8_+_45627946 0.426 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_-_59163696 0.419 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr6_-_114969986 0.398 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chr8_-_22476809 0.384 ENSMUST00000163774.1
ENSMUST00000033935.8
Smim19

small integral membrane protein 19

chr9_-_70141484 0.374 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr5_+_32458974 0.372 ENSMUST00000015100.8
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isoform
chr18_+_40258361 0.363 ENSMUST00000091927.4
Kctd16
potassium channel tetramerisation domain containing 16
chr4_-_101844023 0.334 ENSMUST00000106919.1
B020004J07Rik
RIKEN cDNA B020004J07 gene
chr8_+_94386486 0.318 ENSMUST00000034220.7
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr10_+_94576254 0.304 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chrX_+_94724569 0.299 ENSMUST00000101388.2
Zxdb
zinc finger, X-linked, duplicated B
chr7_-_42727017 0.260 ENSMUST00000166837.1
Gm17067
predicted gene 17067
chr11_+_69846374 0.223 ENSMUST00000108632.1
Plscr3
phospholipid scramblase 3
chr13_+_45965211 0.155 ENSMUST00000038032.3
5033430I15Rik
RIKEN cDNA 5033430I15 gene
chr11_-_5152218 0.149 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr19_-_4334001 0.126 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr7_-_44892358 0.125 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr6_-_86793522 0.096 ENSMUST00000001187.8
Anxa4
annexin A4
chr11_+_51763682 0.091 ENSMUST00000020653.5
Sar1b
SAR1 gene homolog B (S. cerevisiae)
chr17_-_15564322 0.025 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chr10_+_127195240 0.011 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.3 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.7 8.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.6 4.8 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.6 14.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.4 4.2 GO:0034334 adherens junction maintenance(GO:0034334)
1.1 3.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.1 3.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.9 6.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 4.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.8 6.5 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.7 7.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.7 7.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.7 2.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 2.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.6 1.8 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.6 3.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.6 1.7 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.5 2.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.5 3.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.5 2.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 2.3 GO:0030242 pexophagy(GO:0030242)
0.4 1.8 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.4 1.3 GO:0030070 insulin processing(GO:0030070)
0.4 2.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 1.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.4 2.5 GO:0019695 choline metabolic process(GO:0019695)
0.4 1.2 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.4 1.2 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.4 4.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4 1.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 6.7 GO:0045475 locomotor rhythm(GO:0045475)
0.3 2.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 3.6 GO:1990403 embryonic brain development(GO:1990403)
0.2 3.4 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 1.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 1.8 GO:0031424 keratinization(GO:0031424)
0.2 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 2.0 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 4.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 4.9 GO:0009409 response to cold(GO:0009409)
0.2 3.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.2 1.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 3.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.9 GO:0098543 detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.1 0.8 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 1.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.6 GO:0007413 axonal fasciculation(GO:0007413)
0.1 2.1 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.1 0.6 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 7.0 GO:0051592 response to calcium ion(GO:0051592)
0.1 2.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 9.8 GO:0006338 chromatin remodeling(GO:0006338)
0.1 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 2.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.5 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 3.3 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.3 GO:0097418 neurofibrillary tangle(GO:0097418)
1.0 8.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 14.0 GO:0031430 M band(GO:0031430)
0.5 7.4 GO:0043203 axon hillock(GO:0043203)
0.5 10.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.5 1.9 GO:0031673 H zone(GO:0031673)
0.5 1.8 GO:0001533 cornified envelope(GO:0001533)
0.4 4.9 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.2 GO:1990037 Lewy body core(GO:1990037)
0.4 1.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 14.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 3.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 4.4 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.2 7.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 4.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.5 GO:1990879 CST complex(GO:1990879)
0.1 2.2 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.5 GO:0005605 basal lamina(GO:0005605)
0.1 3.6 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 2.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.1 GO:0032420 stereocilium(GO:0032420)
0.0 2.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 5.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 7.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.4 GO:0030426 growth cone(GO:0030426)
0.0 5.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.8 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0004962 endothelin receptor activity(GO:0004962)
1.3 6.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.3 3.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.8 3.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.6 2.5 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.6 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 11.3 GO:0051787 misfolded protein binding(GO:0051787)
0.5 1.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.5 14.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 7.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 2.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.3 1.7 GO:0086080 connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 6.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 7.3 GO:0045296 cadherin binding(GO:0045296)
0.2 3.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 0.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 3.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 4.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 2.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 3.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.5 GO:0010181 FMN binding(GO:0010181)
0.1 2.0 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 5.5 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 3.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 3.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.2 GO:0030332 cyclin binding(GO:0030332)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 2.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.4 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)