Motif ID: Ddit3

Z-value: 0.991


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.411.5e-03Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Showing 1 to 20 of 146 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_109823585 12.021 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr5_+_137553517 10.533 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
 Actl6b




actin-like 6B




chr19_-_59076069 8.776 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr11_-_35798884 8.348 ENSMUST00000160726.2
 Fbll1
fibrillarin-like 1
chr9_-_121495678 7.437 ENSMUST00000035120.4
 Cck
cholecystokinin
chr15_-_66948419 7.287 ENSMUST00000167817.1
 Ndrg1
N-myc downstream regulated gene 1
chr6_+_21215472 6.656 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr10_+_112271123 6.495 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chrX_+_166238901 6.444 ENSMUST00000112235.1
 Gpm6b
glycoprotein m6b
chrX_+_103422010 6.260 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr3_+_9403049 5.065 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
 C030034L19Rik


RIKEN cDNA C030034L19 gene


chr15_-_43869993 4.918 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr8_-_99416397 4.899 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
 Cdh8




cadherin 8




chr1_-_5019342 4.839 ENSMUST00000002533.8
 Rgs20
regulator of G-protein signaling 20
chr14_-_103843685 4.765 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr18_+_37307445 4.491 ENSMUST00000056712.2
 Pcdhb4
protocadherin beta 4
chr7_-_126082406 4.430 ENSMUST00000073935.5
 Gsg1l
GSG1-like
chr7_+_126776939 4.241 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr15_-_59082026 4.168 ENSMUST00000080371.6
 Mtss1
metastasis suppressor 1
chr18_+_37421418 4.138 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 14.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.9 11.3 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 9.8 GO:0006338 chromatin remodeling(GO:0006338)
1.7 8.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.7 7.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.7 7.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 7.0 GO:0051592 response to calcium ion(GO:0051592)
0.3 6.7 GO:0045475 locomotor rhythm(GO:0045475)
0.8 6.5 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.9 6.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 4.9 GO:0009409 response to cold(GO:0009409)
1.6 4.8 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.4 4.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 4.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.4 4.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.8 4.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.5 3.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.3 3.6 GO:1990403 embryonic brain development(GO:1990403)
0.1 3.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.6 3.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 14.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.6 14.0 GO:0031430 M band(GO:0031430)
1.6 11.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.5 10.5 GO:0016514 SWI/SNF complex(GO:0016514)
1.0 8.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 7.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.5 7.4 GO:0043203 axon hillock(GO:0043203)
0.2 7.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 5.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 5.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 4.9 GO:0043083 synaptic cleft(GO:0043083)
0.2 4.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 4.4 GO:0032279 asymmetric synapse(GO:0032279)
0.3 3.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 3.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 3.4 GO:0030426 growth cone(GO:0030426)
0.0 3.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.5 GO:0005605 basal lamina(GO:0005605)
0.0 2.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 14.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 11.3 GO:0051787 misfolded protein binding(GO:0051787)
0.4 7.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 7.3 GO:0045296 cadherin binding(GO:0045296)
1.3 6.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 6.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 5.5 GO:0042054 histone methyltransferase activity(GO:0042054)
1.6 4.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 4.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.8 3.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.3 3.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 3.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 3.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 3.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.4 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2 3.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 3.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.2 GO:0030332 cyclin binding(GO:0030332)