Motif ID: Dmc1
Z-value: 0.738
Transcription factors associated with Dmc1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Dmc1 | ENSMUSG00000022429.10 | Dmc1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Dmc1 | mm10_v2_chr15_-_79605084_79605114 | 0.16 | 2.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.6 | 2.5 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 0.6 | 1.8 | GO:0097402 | neuroblast migration(GO:0097402) |
| 0.4 | 2.6 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.4 | 1.6 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 0.4 | 1.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.3 | 1.9 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 0.9 | GO:0032632 | interleukin-3 production(GO:0032632) |
| 0.3 | 3.6 | GO:0097067 | negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.3 | 4.1 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.3 | 3.8 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.3 | 0.8 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
| 0.3 | 0.8 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.3 | 0.3 | GO:0048389 | intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) ureter urothelium development(GO:0072190) |
| 0.3 | 0.8 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.2 | 0.5 | GO:0070232 | T cell apoptotic process(GO:0070231) regulation of T cell apoptotic process(GO:0070232) |
| 0.2 | 0.2 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 0.2 | 1.5 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.2 | 2.6 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.2 | 0.9 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 0.2 | 1.1 | GO:0072683 | T cell extravasation(GO:0072683) |
| 0.2 | 0.9 | GO:0097494 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494) |
| 0.2 | 0.8 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.2 | 0.6 | GO:0019659 | glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.2 | 0.5 | GO:0010248 | B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.2 | 4.1 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.2 | 1.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.2 | 1.5 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
| 0.2 | 0.5 | GO:0048211 | Golgi vesicle docking(GO:0048211) |
| 0.2 | 6.1 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 0.5 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.2 | 0.7 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.2 | 0.5 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.2 | 0.5 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.1 | 0.7 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 2.6 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.1 | 0.4 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.1 | 0.4 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 0.3 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.1 | 0.4 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.1 | 0.7 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.1 | 0.4 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.1 | 0.5 | GO:0071105 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
| 0.1 | 0.4 | GO:0042713 | operant conditioning(GO:0035106) sperm ejaculation(GO:0042713) |
| 0.1 | 0.5 | GO:0031033 | myosin filament organization(GO:0031033) |
| 0.1 | 0.2 | GO:0006404 | RNA import into nucleus(GO:0006404) |
| 0.1 | 0.4 | GO:0070649 | meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649) |
| 0.1 | 0.5 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 0.1 | 0.9 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 0.6 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 0.4 | GO:0000019 | regulation of mitotic recombination(GO:0000019) negative regulation of telomere capping(GO:1904354) |
| 0.1 | 0.4 | GO:0046655 | glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655) |
| 0.1 | 0.3 | GO:0060558 | regulation of calcidiol 1-monooxygenase activity(GO:0060558) |
| 0.1 | 0.9 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 0.3 | GO:0051030 | snRNA transport(GO:0051030) |
| 0.1 | 0.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 0.7 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.1 | 0.5 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of dendritic spine maintenance(GO:1902950) positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.1 | 0.4 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.1 | 0.3 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 0.5 | GO:0071467 | cellular response to pH(GO:0071467) |
| 0.1 | 0.5 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.1 | 0.4 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.5 | GO:0021984 | adenohypophysis development(GO:0021984) |
| 0.1 | 2.5 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.1 | 0.6 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.1 | 0.6 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.1 | 0.2 | GO:0042148 | strand invasion(GO:0042148) |
| 0.1 | 0.4 | GO:0060763 | mammary duct terminal end bud growth(GO:0060763) |
| 0.1 | 0.2 | GO:0071336 | regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
| 0.1 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 0.2 | GO:2000334 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.1 | 0.7 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.1 | 0.3 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.4 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 0.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.2 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.1 | 1.8 | GO:0070670 | response to interleukin-4(GO:0070670) |
| 0.1 | 0.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.1 | 0.5 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.1 | 1.2 | GO:0021854 | hypothalamus development(GO:0021854) |
| 0.1 | 0.3 | GO:1902534 | single-organism membrane invagination(GO:1902534) |
| 0.1 | 0.2 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
| 0.1 | 1.0 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.1 | 0.2 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 0.1 | 0.5 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.1 | 1.5 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 0.5 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.9 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.1 | 4.6 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.1 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 0.2 | GO:0010958 | regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) |
| 0.1 | 0.5 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.1 | 0.9 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.4 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 1.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 0.7 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.1 | 0.2 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 0.2 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.0 | 0.7 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.2 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
| 0.0 | 0.6 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 0.7 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.0 | 0.5 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 0.0 | 0.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.3 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) |
| 0.0 | 0.4 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.0 | 0.8 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.0 | 1.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.3 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.6 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.2 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.0 | 0.1 | GO:0090289 | regulation of osteoclast proliferation(GO:0090289) |
| 0.0 | 0.2 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 0.4 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.0 | 0.5 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
| 0.0 | 0.5 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
| 0.0 | 0.1 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
| 0.0 | 0.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.0 | 0.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.0 | 0.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.3 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 0.5 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.6 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 0.1 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.0 | 0.3 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 1.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.0 | GO:0071898 | regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
| 0.0 | 0.3 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.7 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 0.1 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
| 0.0 | 0.0 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.9 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.4 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.0 | 0.2 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 0.7 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.1 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.0 | 0.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.0 | 0.3 | GO:0042098 | T cell proliferation(GO:0042098) |
| 0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.0 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) |
| 0.0 | 0.1 | GO:0044830 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) modulation by host of viral RNA genome replication(GO:0044830) |
| 0.0 | 0.8 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.0 | 1.1 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.0 | 0.4 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.0 | 0.4 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.0 | GO:0002360 | T cell lineage commitment(GO:0002360) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) |
| 0.0 | 0.6 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.0 | 0.2 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 0.7 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.0 | 0.2 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.0 | 0.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 0.3 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 0.2 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.0 | 0.7 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.0 | 0.1 | GO:0042756 | drinking behavior(GO:0042756) |
| 0.0 | 0.1 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 0.3 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 1.4 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.0 | 0.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 1.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.8 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.1 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 0.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.8 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
| 0.0 | 0.8 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.6 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.2 | GO:0001709 | cell fate determination(GO:0001709) |
| 0.0 | 1.0 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 1.2 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.0 | 0.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.0 | GO:2001197 | positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.4 | GO:0006360 | transcription from RNA polymerase I promoter(GO:0006360) |
| 0.0 | 0.2 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.2 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 3.0 | GO:0007015 | actin filament organization(GO:0007015) |
| 0.0 | 1.0 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
| 0.0 | 0.1 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.5 | 4.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.4 | 1.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 0.9 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.2 | 0.7 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 1.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 0.6 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.2 | 0.6 | GO:0044299 | C-fiber(GO:0044299) |
| 0.2 | 0.9 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.2 | 2.0 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.2 | 1.0 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.2 | 0.5 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.2 | 1.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.8 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 2.6 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 0.7 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.1 | 0.5 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 0.7 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.8 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.9 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 0.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.5 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 0.6 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 7.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 0.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.4 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 0.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 0.5 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 1.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.3 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.1 | 0.8 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 0.7 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597) |
| 0.1 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 0.2 | GO:0070449 | elongin complex(GO:0070449) |
| 0.0 | 0.7 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 1.9 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.2 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 0.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.0 | 0.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.4 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.1 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.0 | 0.5 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 2.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 7.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.2 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.0 | 0.8 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.1 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.0 | 0.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 0.5 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.1 | GO:0044301 | climbing fiber(GO:0044301) parallel fiber(GO:1990032) |
| 0.0 | 0.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.5 | GO:0005865 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 1.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.8 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.3 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.1 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.0 | 0.5 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.3 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 1.6 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 1.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.3 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 0.7 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.0 | 0.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.1 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.6 | GO:0030880 | RNA polymerase complex(GO:0030880) |
| 0.0 | 0.8 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.5 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.3 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.1 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 4.3 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 0.5 | 1.6 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.3 | 1.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.3 | 1.1 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.3 | 0.8 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 1.5 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.2 | 1.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.2 | 3.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 0.9 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.2 | 0.6 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 0.2 | 1.8 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.2 | 0.9 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.2 | 0.5 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.2 | 1.5 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 0.5 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.2 | 0.5 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.2 | 0.5 | GO:0019863 | IgE binding(GO:0019863) |
| 0.2 | 1.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 0.6 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 0.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 0.4 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.1 | 0.4 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.1 | 0.4 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) IgG receptor activity(GO:0019770) |
| 0.1 | 1.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 0.4 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 1.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 0.9 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 0.5 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.1 | 0.2 | GO:0042281 | alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281) |
| 0.1 | 0.7 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 0.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.5 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 0.1 | 0.4 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 0.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.4 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 1.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 1.8 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 0.3 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.4 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 1.0 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 2.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 3.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.9 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.1 | 0.4 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.1 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.6 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.2 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142) |
| 0.1 | 0.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.1 | 0.8 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.1 | 0.4 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 0.8 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.2 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 0.3 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 2.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 0.3 | GO:0050062 | long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.5 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.1 | 1.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 0.5 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 1.9 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 0.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 3.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.2 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.5 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 1.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.9 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.7 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.0 | 0.2 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 1.1 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.3 | GO:0005536 | glucose binding(GO:0005536) |
| 0.0 | 0.4 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.0 | 0.4 | GO:0042556 | cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.0 | 0.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.1 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 0.5 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.3 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) |
| 0.0 | 0.7 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 0.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.0 | 0.1 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.0 | 0.8 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 8.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.2 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 0.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.2 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.1 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.0 | 1.2 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.7 | GO:0043236 | laminin binding(GO:0043236) |
| 0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.2 | GO:0035312 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.5 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.0 | 0.1 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.0 | 0.1 | GO:0042806 | fucose binding(GO:0042806) oligosaccharide binding(GO:0070492) |
| 0.0 | 0.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.0 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.1 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.0 | 0.8 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.2 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 7.6 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 1.0 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.2 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 0.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 0.2 | GO:0035925 | translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.1 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.2 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 1.8 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.3 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 4.6 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.1 | GO:0016918 | retinal binding(GO:0016918) |
| 0.0 | 0.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.2 | GO:0002039 | p53 binding(GO:0002039) |
