Motif ID: E2f7
Z-value: 1.296
Transcription factors associated with E2f7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
E2f7 | ENSMUSG00000020185.10 | E2f7 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f7 | mm10_v2_chr10_+_110745433_110745572 | 0.50 | 4.6e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 11.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
1.9 | 7.5 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
1.3 | 13.0 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
1.2 | 6.0 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
1.1 | 3.2 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
1.0 | 4.8 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.9 | 2.7 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.8 | 2.5 | GO:0040009 | regulation of growth rate(GO:0040009) protein poly-ADP-ribosylation(GO:0070212) |
0.6 | 2.5 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.6 | 1.8 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.6 | 2.3 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.5 | 4.9 | GO:1901970 | positive regulation of mitotic sister chromatid separation(GO:1901970) |
0.5 | 4.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.5 | 2.6 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.5 | 3.6 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
0.5 | 2.0 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.5 | 7.0 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.5 | 2.3 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.5 | 6.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.4 | 3.8 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.4 | 2.5 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.4 | 2.0 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.4 | 1.1 | GO:0071139 | resolution of recombination intermediates(GO:0071139) |
0.4 | 1.5 | GO:1904008 | response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
0.4 | 4.8 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.3 | 1.3 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.3 | 1.2 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.2 | 4.3 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
0.2 | 0.6 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.2 | 4.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.2 | 2.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.2 | 1.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.2 | 3.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.2 | 0.5 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.2 | 1.9 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.2 | 1.1 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
0.1 | 2.2 | GO:0043486 | histone exchange(GO:0043486) |
0.1 | 4.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 1.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 0.6 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 0.5 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.1 | 3.1 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.1 | 1.9 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.1 | 3.8 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.1 | 3.6 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.1 | 1.3 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
0.1 | 0.5 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.1 | 1.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.1 | 2.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 1.9 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.3 | GO:0042984 | very-low-density lipoprotein particle assembly(GO:0034379) amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
0.0 | 1.1 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.5 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.4 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.0 | 0.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.8 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 0.4 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
0.0 | 0.2 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.0 | 0.1 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.0 | 0.0 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 13.0 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
1.3 | 10.4 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
1.0 | 11.4 | GO:0005915 | zonula adherens(GO:0005915) |
0.8 | 2.5 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.8 | 3.2 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.8 | 2.3 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.5 | 7.5 | GO:0042555 | MCM complex(GO:0042555) |
0.4 | 2.0 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476) |
0.4 | 2.0 | GO:0001651 | dense fibrillar component(GO:0001651) granular component(GO:0001652) |
0.2 | 3.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.2 | 1.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.2 | 1.5 | GO:0005638 | lamin filament(GO:0005638) |
0.2 | 7.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.2 | 1.2 | GO:0044613 | nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543) |
0.2 | 0.6 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.1 | 10.3 | GO:0072686 | mitotic spindle(GO:0072686) |
0.1 | 0.5 | GO:0032021 | NELF complex(GO:0032021) |
0.1 | 0.8 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.1 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 1.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 1.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 5.6 | GO:0000922 | spindle pole(GO:0000922) |
0.1 | 1.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 0.6 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 2.1 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) |
0.0 | 3.7 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 1.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.4 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.0 | 2.2 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 1.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.1 | GO:0070695 | FHF complex(GO:0070695) |
0.0 | 0.5 | GO:0005844 | polysome(GO:0005844) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 13.0 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
1.5 | 6.0 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
1.1 | 13.7 | GO:0070097 | delta-catenin binding(GO:0070097) |
1.0 | 7.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.9 | 3.7 | GO:0043515 | kinetochore binding(GO:0043515) |
0.8 | 3.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.7 | 4.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.7 | 2.7 | GO:0019808 | polyamine binding(GO:0019808) |
0.6 | 3.8 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.5 | 2.3 | GO:0070883 | importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883) |
0.4 | 2.5 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.4 | 1.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.4 | 2.5 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
0.3 | 5.9 | GO:0035173 | histone kinase activity(GO:0035173) |
0.3 | 2.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.2 | 1.2 | GO:0051425 | PTB domain binding(GO:0051425) |
0.2 | 1.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 3.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.2 | 1.9 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.2 | 0.6 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.1 | 1.3 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 1.1 | GO:0036222 | XTP diphosphatase activity(GO:0036222) |
0.1 | 3.0 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.1 | 2.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.1 | 0.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.1 | 1.5 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 5.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.6 | GO:0048038 | quinone binding(GO:0048038) |
0.0 | 3.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 2.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 1.2 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 2.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 6.6 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.2 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.0 | 2.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.0 | 1.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 7.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 2.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 3.3 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 2.9 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 4.7 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.5 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
0.0 | 4.4 | GO:0003682 | chromatin binding(GO:0003682) |