Motif ID: Elf1_Elf2_Etv2_Elf4

Z-value: 2.744

Transcription factors associated with Elf1_Elf2_Etv2_Elf4:

Gene SymbolEntrez IDGene Name
Elf1 ENSMUSG00000036461.9 Elf1
Elf2 ENSMUSG00000037174.12 Elf2
Elf4 ENSMUSG00000031103.6 Elf4
Etv2 ENSMUSG00000006311.8 Etv2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf4mm10_v2_chrX_-_48454152_484541930.471.8e-04Click!
Elf1mm10_v2_chr14_+_79481164_79481194-0.453.5e-04Click!
Elf2mm10_v2_chr3_-_51340628_51340681-0.453.9e-04Click!


Activity profile for motif Elf1_Elf2_Etv2_Elf4.

activity profile for motif Elf1_Elf2_Etv2_Elf4


Sorted Z-values histogram for motif Elf1_Elf2_Etv2_Elf4

Sorted Z-values for motif Elf1_Elf2_Etv2_Elf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf1_Elf2_Etv2_Elf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 27.504 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_5845243 21.498 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_-_94653964 20.124 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_-_156839790 18.693 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr1_-_180330550 18.475 ENSMUST00000050581.3
 Gm5069
predicted pseudogene 5069
chr1_+_84839833 17.381 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr16_-_22161450 17.310 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr16_-_18811972 16.448 ENSMUST00000000028.7
ENSMUST00000115585.1
 Cdc45

cell division cycle 45

chr3_-_89418287 16.233 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr9_-_57836706 15.640 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr2_+_5845017 14.994 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr4_-_45320580 14.831 ENSMUST00000030003.3
 Exosc3
exosome component 3
chr6_+_117906809 14.320 ENSMUST00000177918.1
ENSMUST00000163168.2
 Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr4_+_124850679 13.837 ENSMUST00000102628.4
 Yrdc
yrdC domain containing (E.coli)
chr19_+_6084983 13.528 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr7_-_126792469 12.839 ENSMUST00000032936.6
 Ppp4c
protein phosphatase 4, catalytic subunit
chr19_-_40271506 12.461 ENSMUST00000068439.6
 Pdlim1
PDZ and LIM domain 1 (elfin)
chr7_-_127042420 12.383 ENSMUST00000032915.6
 Kif22
kinesin family member 22
chr11_-_69921057 12.095 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr11_-_12037391 11.988 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,026 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 261.9 GO:0008380 RNA splicing(GO:0008380)
1.1 101.5 GO:0006413 translational initiation(GO:0006413)
2.3 86.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.1 76.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.3 70.6 GO:0006412 translation(GO:0006412)
3.5 69.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.2 58.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.3 51.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.5 49.6 GO:0006284 base-excision repair(GO:0006284)
1.1 48.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.3 44.2 GO:0002181 cytoplasmic translation(GO:0002181)
2.7 38.3 GO:0010388 cullin deneddylation(GO:0010388)
0.6 38.2 GO:0051028 mRNA transport(GO:0051028)
6.3 37.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.4 35.9 GO:0030488 tRNA methylation(GO:0030488)
0.4 34.5 GO:0042254 ribosome biogenesis(GO:0042254)
4.1 32.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 31.6 GO:0043966 histone H3 acetylation(GO:0043966)
1.7 29.4 GO:0006270 DNA replication initiation(GO:0006270)
1.0 28.6 GO:0051310 metaphase plate congression(GO:0051310)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 402 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 281.4 GO:0005730 nucleolus(GO:0005730)
2.5 179.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.6 137.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
2.7 130.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 79.4 GO:0005681 spliceosomal complex(GO:0005681)
1.3 62.5 GO:0008180 COP9 signalosome(GO:0008180)
5.0 60.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 51.6 GO:0005654 nucleoplasm(GO:0005654)
1.2 49.3 GO:0015934 large ribosomal subunit(GO:0015934)
1.7 48.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.6 45.0 GO:0030684 preribosome(GO:0030684)
3.0 44.7 GO:0042555 MCM complex(GO:0042555)
1.6 44.5 GO:0015030 Cajal body(GO:0015030)
0.2 43.1 GO:0005667 transcription factor complex(GO:0005667)
5.9 41.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 40.8 GO:0000790 nuclear chromatin(GO:0000790)
0.7 38.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.7 37.3 GO:0072686 mitotic spindle(GO:0072686)
3.4 33.6 GO:0031595 nuclear proteasome complex(GO:0031595)
2.4 33.6 GO:0000974 Prp19 complex(GO:0000974)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 594 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 246.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 233.2 GO:0044822 poly(A) RNA binding(GO:0044822)
1.8 114.0 GO:0003743 translation initiation factor activity(GO:0003743)
1.5 88.8 GO:0019843 rRNA binding(GO:0019843)
1.4 73.0 GO:0000049 tRNA binding(GO:0000049)
1.2 70.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.9 64.4 GO:0003697 single-stranded DNA binding(GO:0003697)
2.1 59.3 GO:0030515 snoRNA binding(GO:0030515)
2.6 56.4 GO:0017025 TBP-class protein binding(GO:0017025)
6.0 48.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.7 46.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
5.0 44.7 GO:1990446 U1 snRNP binding(GO:1990446)
0.9 44.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
4.8 43.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 41.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
5.1 40.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.4 39.6 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.3 38.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 34.6 GO:0042393 histone binding(GO:0042393)
0.2 34.6 GO:0003723 RNA binding(GO:0003723)