Motif ID: Elf3

Z-value: 1.033


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.548.3e-06Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_146502141 9.376 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr19_+_25406661 7.619 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr18_+_56432116 6.349 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr10_-_83648713 5.380 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr14_-_70207637 5.319 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr16_+_62854299 5.119 ENSMUST00000023629.8
Pros1
protein S (alpha)
chr11_-_55419898 5.029 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr19_-_50678642 4.959 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr6_-_146502099 4.917 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr7_+_101378183 4.852 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_-_23248264 4.685 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr19_-_50678485 4.639 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr10_+_79988584 4.522 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr19_+_16435616 4.521 ENSMUST00000025602.2
Gna14
guanine nucleotide binding protein, alpha 14
chr13_+_13437602 4.474 ENSMUST00000005532.7
Nid1
nidogen 1
chr17_+_35049966 4.395 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr12_-_65172560 4.326 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr17_+_86963279 4.189 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr11_+_115163333 4.089 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr11_+_53770014 3.968 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 130 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 14.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 10.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 9.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
1.4 8.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
2.1 8.5 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
2.5 7.4 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 6.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
2.0 6.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.1 5.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.8 5.4 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 5.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.6 5.1 GO:0042730 fibrinolysis(GO:0042730)
0.2 5.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.8 4.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 4.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.5 4.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.3 4.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.5 4.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.7 4.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.9 3.8 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 14.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 10.9 GO:0072562 blood microparticle(GO:0072562)
0.3 8.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 7.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 7.8 GO:0005925 focal adhesion(GO:0005925)
0.3 7.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.9 6.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 6.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 5.2 GO:0005884 actin filament(GO:0005884)
1.3 5.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.8 GO:0005901 caveola(GO:0005901)
0.2 4.5 GO:0005605 basal lamina(GO:0005605)
0.0 4.4 GO:0016607 nuclear speck(GO:0016607)
0.0 4.4 GO:0000790 nuclear chromatin(GO:0000790)
1.4 4.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 4.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 4.2 GO:0000776 kinetochore(GO:0000776)
0.8 4.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 4.1 GO:0031985 Golgi cisterna(GO:0031985)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 19.9 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
4.8 14.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5 8.7 GO:0017166 vinculin binding(GO:0017166)
0.5 7.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 7.0 GO:0005525 GTP binding(GO:0005525)
0.6 6.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 6.6 GO:0030165 PDZ domain binding(GO:0030165)
0.3 5.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 5.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 4.6 GO:0008013 beta-catenin binding(GO:0008013)
0.6 4.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 4.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
1.1 4.3 GO:0035877 death effector domain binding(GO:0035877)
0.3 4.2 GO:0005522 profilin binding(GO:0005522)
0.0 4.2 GO:0005516 calmodulin binding(GO:0005516)
0.5 4.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
1.0 3.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 3.8 GO:0050897 cobalt ion binding(GO:0050897)
0.3 3.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6 3.5 GO:0050786 RAGE receptor binding(GO:0050786)