Motif ID: Emx1_Emx2

Z-value: 0.626

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx1mm10_v2_chr6_+_85187438_851875100.621.3e-07Click!
Emx2mm10_v2_chr19_+_59458372_59458450-0.392.4e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_82505749 9.563 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_82505274 8.583 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr4_-_82505707 8.429 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr1_-_158356258 4.164 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr10_+_81257277 3.258 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr9_-_20728219 3.126 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr3_+_127633134 2.967 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr17_-_36032682 2.570 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr10_+_90071095 2.522 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_156392829 2.518 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr16_-_97170707 2.365 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr17_-_31636631 2.315 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr1_+_32172711 2.262 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr4_+_118961578 1.954 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr16_-_63864114 1.904 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr15_+_99006056 1.887 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr7_-_103827922 1.883 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr11_-_42000284 1.880 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr9_+_34904913 1.569 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr1_+_93685574 1.519 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr8_-_125898291 1.502 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr5_-_118244861 1.442 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr16_+_11406618 1.437 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr14_+_58893465 1.396 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr7_+_126781483 1.329 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr6_-_144209448 1.294 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr12_-_90969768 1.293 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr6_-_144209558 1.245 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr2_-_5676046 1.200 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr6_-_144209471 1.173 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr13_+_16014457 1.165 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr17_-_47043039 1.140 ENSMUST00000075152.5
Gm4945
predicted gene 4945
chr10_+_81183000 1.112 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr10_+_69787431 1.079 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr2_-_157566319 1.045 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr15_-_33687840 0.988 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr16_-_26371828 0.980 ENSMUST00000023154.2
Cldn1
claudin 1
chr7_-_97738222 0.973 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr7_+_43672003 0.966 ENSMUST00000038332.8
Ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr13_-_23934156 0.954 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr8_+_85432686 0.952 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr17_-_32822200 0.950 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr8_-_21906412 0.933 ENSMUST00000051965.4
Defb11
defensin beta 11
chr8_+_72219726 0.863 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr11_+_121237216 0.836 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr6_-_57535422 0.833 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr6_+_79818031 0.827 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr4_+_110397661 0.824 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr8_+_93810832 0.809 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr12_-_84617326 0.807 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr7_-_30534180 0.800 ENSMUST00000044338.4
Arhgap33
Rho GTPase activating protein 33
chr6_+_129533183 0.799 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr12_-_12940600 0.777 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr9_+_108648720 0.758 ENSMUST00000098384.2
Gm10621
predicted gene 10621
chr8_+_45507768 0.743 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr15_-_102510681 0.741 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr8_+_69300776 0.737 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr10_-_49783259 0.727 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr9_-_15301555 0.716 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr17_+_46772635 0.715 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr1_-_40085823 0.707 ENSMUST00000181756.1
Gm16894
predicted gene, 16894
chr2_-_34826071 0.674 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr7_+_39588931 0.671 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr1_+_163779575 0.666 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr4_+_102589687 0.655 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr14_+_55560010 0.644 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr4_+_110397764 0.631 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr4_-_64276595 0.625 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr4_+_126609818 0.623 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr15_+_99295087 0.595 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr18_-_6241486 0.579 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr10_+_79996479 0.571 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_+_135009152 0.569 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr9_+_56418624 0.565 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr2_-_93452679 0.555 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr17_+_29274078 0.549 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr2_-_34826187 0.521 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr1_-_184999549 0.510 ENSMUST00000027929.4
Mark1
MAP/microtubule affinity-regulating kinase 1
chr3_+_32436376 0.501 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr3_-_37125943 0.495 ENSMUST00000029275.5
Il2
interleukin 2
chr4_-_150914401 0.474 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr4_-_155645408 0.466 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr6_-_129533267 0.436 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr13_+_23555023 0.428 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr13_-_99516537 0.427 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr8_-_85432841 0.418 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr3_-_130730375 0.417 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr3_+_146852359 0.410 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr4_-_134245579 0.405 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr4_+_32657107 0.393 ENSMUST00000071642.4
ENSMUST00000178134.1
Mdn1

midasin homolog (yeast)

chr14_-_18893376 0.392 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr8_+_34054622 0.387 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chrX_-_150814265 0.384 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr17_-_45599603 0.381 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr11_+_72689997 0.367 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr7_-_5413145 0.360 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr4_+_83417715 0.357 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr7_+_129591859 0.354 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr2_+_144594054 0.351 ENSMUST00000136628.1
Gm561
predicted gene 561
chr3_+_121953213 0.342 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr3_+_121531603 0.339 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr3_+_32436151 0.329 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr10_-_88605017 0.328 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr2_-_160619971 0.324 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chrX_-_102505359 0.312 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr2_-_37647199 0.279 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chrX_-_59166080 0.272 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr5_-_139345149 0.258 ENSMUST00000049630.6
Cox19
cytochrome c oxidase assembly protein 19
chr4_+_145510759 0.249 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr14_-_57133585 0.246 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr6_-_89595647 0.245 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr9_-_53667429 0.242 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chrX_-_160994665 0.222 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr15_-_36496722 0.222 ENSMUST00000057486.7
Ankrd46
ankyrin repeat domain 46
chr13_-_92030897 0.220 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr5_-_121502980 0.218 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr16_+_21794320 0.214 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr8_-_8690493 0.206 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr4_+_41966058 0.202 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chr18_-_6241470 0.196 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr12_-_87444017 0.190 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr1_-_37496095 0.182 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr12_+_36314160 0.177 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chrX_-_134111852 0.177 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr10_+_128322443 0.150 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr13_-_97747373 0.145 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_+_45734506 0.143 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr7_+_126976338 0.140 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr13_+_94976435 0.139 ENSMUST00000160409.1
ENSMUST00000159647.1
ENSMUST00000167155.1
Wdr41


WD repeat domain 41


chr17_-_45686899 0.136 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr11_+_5788480 0.133 ENSMUST00000109845.1
ENSMUST00000020769.7
ENSMUST00000102928.4
Dbnl


drebrin-like


chrX_-_74393003 0.133 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr2_+_175372436 0.132 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr3_+_88716884 0.130 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chr11_+_6560183 0.124 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr3_+_88716838 0.122 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr17_+_14943184 0.121 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chr2_-_175703646 0.116 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr2_+_151543877 0.115 ENSMUST00000142271.1
Fkbp1a
FK506 binding protein 1a
chr2_+_69789647 0.112 ENSMUST00000112266.1
Phospho2
phosphatase, orphan 2
chr6_+_124304646 0.111 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr2_+_36230426 0.107 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr15_+_80711292 0.106 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr2_+_175469985 0.099 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr9_+_72958785 0.080 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr2_-_12419387 0.079 ENSMUST00000124515.1
Fam188a
family with sequence similarity 188, member A
chrX_+_106027300 0.066 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_155930190 0.061 ENSMUST00000109636.4
ENSMUST00000109631.1
Uqcc1

ubiquinol-cytochrome c reductase complex assembly factor 1

chr13_-_97747399 0.060 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr19_+_34217588 0.054 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chrX_+_106027259 0.050 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr3_-_146495115 0.048 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr4_-_149099802 0.046 ENSMUST00000103217.4
Pex14
peroxisomal biogenesis factor 14
chr6_-_101377342 0.045 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr9_-_124304718 0.043 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr1_-_23909687 0.038 ENSMUST00000129254.1
Smap1
small ArfGAP 1
chr3_-_151749877 0.032 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr19_-_32196393 0.011 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 26.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.9 2.6 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.8 2.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.8 1.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.8 2.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.6 1.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 1.1 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.4 1.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 3.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 1.3 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.3 1.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 2.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 0.8 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.2 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.2 2.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 1.9 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617)
0.2 1.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 1.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 1.0 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 0.5 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation(GO:0018307) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
0.1 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 1.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 4.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.8 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 3.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.0 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0051542 elastin biosynthetic process(GO:0051542)
0.0 0.1 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 3.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 1.7 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.8 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 26.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.2 GO:0043512 inhibin A complex(GO:0043512)
0.3 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.7 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.2 2.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 3.4 GO:0030426 growth cone(GO:0030426)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 4.2 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.8 26.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 2.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.5 1.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 2.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 1.0 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.2 0.5 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
0.1 0.8 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0051400 BH domain binding(GO:0051400)
0.1 1.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.1 3.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 2.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) superoxide dismutase copper chaperone activity(GO:0016532) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.7 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0048185 activin binding(GO:0048185)