Motif ID: Ep300

Z-value: 0.519


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_81586250-0.211.1e-01Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800344 3.401 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr11_+_98348404 3.365 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr6_+_99692679 2.422 ENSMUST00000101122.1
 Gpr27
G protein-coupled receptor 27
chr9_-_29411736 2.384 ENSMUST00000115236.1
 Ntm
neurotrimin
chr19_+_23758819 2.050 ENSMUST00000025830.7
 Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr7_+_96522342 1.923 ENSMUST00000129737.1
 Tenm4
teneurin transmembrane protein 4
chr14_-_25903100 1.811 ENSMUST00000052286.8
 Plac9a
placenta specific 9a
chr10_+_58813359 1.715 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr11_+_97415527 1.632 ENSMUST00000121799.1
 Arhgap23
Rho GTPase activating protein 23
chr12_-_69372443 1.583 ENSMUST00000053451.1
 Gm9887
predicted gene 9887
chr12_+_84009481 1.534 ENSMUST00000168120.1
 Acot1
acyl-CoA thioesterase 1
chr14_-_25902474 1.530 ENSMUST00000183431.1
ENSMUST00000183725.1
 Plac9a

placenta specific 9a

chr2_-_31845925 1.429 ENSMUST00000028188.7
 Fibcd1
fibrinogen C domain containing 1
chr5_-_39644597 1.402 ENSMUST00000152057.1
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_-_63244135 1.352 ENSMUST00000054837.3
 1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr11_-_116307168 1.278 ENSMUST00000124281.1
 Exoc7
exocyst complex component 7
chr2_+_25054355 1.274 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
 Nsmf



NMDA receptor synaptonuclear signaling and neuronal migration factor



chr8_+_112570043 1.272 ENSMUST00000034225.6
ENSMUST00000118171.1
 Cntnap4

contactin associated protein-like 4

chr5_-_39644634 1.271 ENSMUST00000053116.6
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr2_+_25054396 1.234 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
 Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
1.1 3.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 3.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 3.3 GO:0043087 regulation of GTPase activity(GO:0043087)
0.2 2.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 2.7 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 2.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.8 2.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0 2.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.3 2.1 GO:0005513 detection of calcium ion(GO:0005513)
0.5 1.9 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.0 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.6 GO:0051592 response to calcium ion(GO:0051592)
0.0 1.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 1.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.2 1.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 1.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.4 GO:0030673 axolemma(GO:0030673)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
1.1 3.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 2.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 2.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.4 1.4 GO:0008061 chitin binding(GO:0008061)
0.4 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)