Motif ID: Erg

Z-value: 1.800


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.471.5e-04Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_38713235 22.873 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr12_+_75308308 17.239 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr5_+_75152274 17.158 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr6_-_23248264 14.273 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_+_79988584 13.476 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr11_-_101785252 12.354 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_-_54661666 11.569 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr10_-_58675631 11.548 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr2_+_30078584 11.389 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr9_-_54661870 11.200 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr2_-_101883010 10.397 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr14_-_25769033 9.933 ENSMUST00000069180.7
 Zcchc24
zinc finger, CCHC domain containing 24
chr6_+_134035691 9.926 ENSMUST00000081028.6
ENSMUST00000111963.1
 Etv6

ets variant gene 6 (TEL oncogene)

chr12_-_56536895 9.834 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr2_+_27677234 9.605 ENSMUST00000166775.1
 Rxra
retinoid X receptor alpha
chr6_+_4003926 9.264 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr11_+_90030295 9.182 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chr2_+_27677201 8.818 ENSMUST00000077257.5
 Rxra
retinoid X receptor alpha
chr19_-_24225015 8.601 ENSMUST00000099558.4
 Tjp2
tight junction protein 2
chr1_+_189728264 8.534 ENSMUST00000097442.2
 Ptpn14
protein tyrosine phosphatase, non-receptor type 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 232 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 25.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 21.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
3.7 18.4 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.3 18.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.6 18.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
6.0 18.0 GO:0038203 TORC2 signaling(GO:0038203)
5.7 17.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
2.4 14.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
2.4 14.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 13.9 GO:0071320 cellular response to cAMP(GO:0071320)
1.9 13.6 GO:0007296 vitellogenesis(GO:0007296)
0.8 13.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
2.1 12.8 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
4.2 12.6 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.6 11.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
1.3 11.5 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
2.2 11.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 10.0 GO:0014013 regulation of gliogenesis(GO:0014013)
3.3 9.9 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
3.3 9.8 GO:0021759 globus pallidus development(GO:0021759)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 31.8 GO:0005730 nucleolus(GO:0005730)
0.5 26.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 25.9 GO:0030027 lamellipodium(GO:0030027)
0.1 25.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
2.4 21.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 19.8 GO:0005902 microvillus(GO:0005902)
0.2 19.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 19.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.3 18.0 GO:0031932 TORC2 complex(GO:0031932)
0.2 17.9 GO:0005884 actin filament(GO:0005884)
0.6 16.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.3 14.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.7 13.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 11.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 10.6 GO:0005921 gap junction(GO:0005921)
0.0 10.0 GO:0045177 apical part of cell(GO:0045177)
0.1 9.6 GO:0072562 blood microparticle(GO:0072562)
0.3 8.6 GO:0005721 pericentric heterochromatin(GO:0005721)
2.0 8.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 8.0 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 40.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.8 29.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 29.5 GO:0051015 actin filament binding(GO:0051015)
0.6 25.2 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
2.1 22.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 19.4 GO:0070888 E-box binding(GO:0070888)
0.8 19.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 18.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
3.1 18.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.9 16.0 GO:0017166 vinculin binding(GO:0017166)
0.9 15.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 14.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.8 14.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 13.7 GO:0070491 repressing transcription factor binding(GO:0070491)
4.5 13.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 13.4 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.1 13.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 11.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 9.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 9.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)