Motif ID: Esr1

Z-value: 1.165


Transcription factors associated with Esr1:

Gene SymbolEntrez IDGene Name
Esr1 ENSMUSG00000019768.10 Esr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esr1mm10_v2_chr10_+_4710119_4710166-0.191.4e-01Click!


Activity profile for motif Esr1.

activity profile for motif Esr1


Sorted Z-values histogram for motif Esr1

Sorted Z-values for motif Esr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Esr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_102365111 10.098 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr10_-_77113676 9.811 ENSMUST00000072755.4
ENSMUST00000105409.1
Col18a1

collagen, type XVIII, alpha 1

chr18_+_74442551 9.453 ENSMUST00000121875.1
Myo5b
myosin VB
chr18_+_74442500 9.356 ENSMUST00000074157.6
Myo5b
myosin VB
chr2_-_166155272 9.296 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr11_-_115612491 7.679 ENSMUST00000106507.2
Mif4gd
MIF4G domain containing
chr7_+_144915100 7.577 ENSMUST00000128057.1
Oraov1
oral cancer overexpressed 1
chr2_+_109917639 7.575 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr4_+_124986430 7.545 ENSMUST00000030687.7
Rspo1
R-spondin homolog (Xenopus laevis)
chr9_+_54764748 7.445 ENSMUST00000034830.8
Crabp1
cellular retinoic acid binding protein I
chr7_-_30973399 7.288 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr7_-_30973367 7.121 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr9_-_63711969 7.041 ENSMUST00000154323.1
Smad3
SMAD family member 3
chr7_-_30973464 6.813 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr8_+_84021444 6.765 ENSMUST00000055077.6
Palm3
paralemmin 3
chr12_+_109747903 6.679 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr6_+_66535390 6.613 ENSMUST00000116605.1
Mad2l1
MAD2 mitotic arrest deficient-like 1
chr2_+_122147680 6.519 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr6_-_125165707 6.010 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr2_+_27886416 5.938 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr11_-_90002881 5.579 ENSMUST00000020864.8
Pctp
phosphatidylcholine transfer protein
chr7_+_46847128 5.370 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr9_-_64253617 5.360 ENSMUST00000005066.8
Map2k1
mitogen-activated protein kinase kinase 1
chr14_+_50944499 5.346 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr6_+_66535418 5.321 ENSMUST00000101343.1
Mad2l1
MAD2 mitotic arrest deficient-like 1
chr6_-_125165576 5.291 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr1_-_175692624 5.287 ENSMUST00000027809.7
Opn3
opsin 3
chr6_-_125166463 5.250 ENSMUST00000117757.2
ENSMUST00000073605.8
Gapdh

glyceraldehyde-3-phosphate dehydrogenase

chr8_-_91801948 5.217 ENSMUST00000175795.1
Irx3
Iroquois related homeobox 3 (Drosophila)
chr7_-_126799163 5.101 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr5_+_127632238 5.069 ENSMUST00000118139.1
Glt1d1
glycosyltransferase 1 domain containing 1
chr7_-_126799134 4.834 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr4_+_99955715 4.771 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr19_+_53529100 4.755 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr6_+_4504814 4.749 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr17_+_35439155 4.716 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr10_-_120899067 4.540 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr19_+_25406661 4.529 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr10_-_77113928 4.526 ENSMUST00000149744.1
Col18a1
collagen, type XVIII, alpha 1
chr5_-_130003000 4.398 ENSMUST00000026613.7
Gusb
glucuronidase, beta
chr4_+_150236816 4.331 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr4_+_100095791 4.256 ENSMUST00000039630.5
Ror1
receptor tyrosine kinase-like orphan receptor 1
chr8_+_119446719 4.211 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr17_+_37270214 4.152 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr8_+_114133557 4.049 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr5_-_149051604 4.028 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr4_-_133874682 4.028 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr18_+_34625009 4.024 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr6_+_91515928 3.875 ENSMUST00000040607.4
Lsm3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_89688196 3.839 ENSMUST00000052478.2
Dmrta1
doublesex and mab-3 related transcription factor like family A1
chr3_+_135485605 3.838 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr14_-_98169542 3.835 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr13_+_31806627 3.768 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr4_-_132345715 3.760 ENSMUST00000084250.4
Rcc1
regulator of chromosome condensation 1
chr8_+_114133635 3.739 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr18_+_34624621 3.718 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr1_+_191063001 3.704 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
Nsl1


NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)


chr6_+_138140521 3.676 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr2_+_172549581 3.632 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr4_-_132345686 3.616 ENSMUST00000030726.6
Rcc1
regulator of chromosome condensation 1
chr2_+_130277157 3.564 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chrX_-_16817339 3.554 ENSMUST00000040820.6
Maob
monoamine oxidase B
chr11_+_3202908 3.481 ENSMUST00000179770.1
ENSMUST00000110048.1
Eif4enif1

eukaryotic translation initiation factor 4E nuclear import factor 1

chr17_+_35424870 3.444 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr3_+_104638658 3.443 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr1_+_58393119 3.437 ENSMUST00000050552.8
Bzw1
basic leucine zipper and W2 domains 1
chr11_-_115808068 3.405 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr5_+_122209729 3.359 ENSMUST00000072602.7
ENSMUST00000143560.1
Hvcn1

hydrogen voltage-gated channel 1

chr1_+_135729147 3.343 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr5_-_130002838 3.325 ENSMUST00000111308.1
ENSMUST00000111307.1
Gusb

glucuronidase, beta

chr7_+_46845832 3.259 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr11_+_11115784 3.210 ENSMUST00000056344.4
Vwc2
von Willebrand factor C domain containing 2
chr13_-_24937585 3.187 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr4_+_116708624 3.181 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr10_+_83722865 3.178 ENSMUST00000150459.1
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr13_+_75707484 3.134 ENSMUST00000001583.6
Ell2
elongation factor RNA polymerase II 2
chr4_+_101068983 3.106 ENSMUST00000038463.8
ENSMUST00000106955.1
Raver2

ribonucleoprotein, PTB-binding 2

chr2_-_84727350 3.103 ENSMUST00000028475.8
Clp1
CLP1, cleavage and polyadenylation factor I subunit
chr3_-_96708524 3.072 ENSMUST00000029742.5
ENSMUST00000171249.1
Nudt17

nudix (nucleoside diphosphate linked moiety X)-type motif 17

chr6_+_82052307 3.064 ENSMUST00000149023.1
Eva1a
eva-1 homolog A (C. elegans)
chr2_-_105904484 3.054 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr6_+_29694204 3.044 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr7_-_142656018 3.029 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr17_-_26099257 3.020 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chrX_+_159988433 2.966 ENSMUST00000033665.8
Map3k15
mitogen-activated protein kinase kinase kinase 15
chr13_+_3478226 2.935 ENSMUST00000181708.1
ENSMUST00000180836.1
ENSMUST00000180567.1
2810429I04Rik


RIKEN cDNA 2810429I04 gene


chr18_-_37997543 2.928 ENSMUST00000042944.7
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr19_-_44545836 2.910 ENSMUST00000111985.1
ENSMUST00000063632.7
Sec31b

Sec31 homolog B (S. cerevisiae)

chr16_+_59471775 2.898 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
Mina


myc induced nuclear antigen


chr2_-_101621033 2.894 ENSMUST00000090513.4
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr2_+_154791344 2.887 ENSMUST00000140713.1
ENSMUST00000137333.1
Raly
a
hnRNP-associated with lethal yellow
nonagouti
chr5_+_140331860 2.867 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr13_-_66227573 2.866 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr4_+_3678108 2.863 ENSMUST00000041377.6
ENSMUST00000103010.3
Lyn

Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

chr2_+_71389239 2.799 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr14_+_65358661 2.764 ENSMUST00000066994.6
Zfp395
zinc finger protein 395
chr4_+_137862237 2.717 ENSMUST00000102518.3
Ece1
endothelin converting enzyme 1
chr13_-_99900645 2.690 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr18_+_24205937 2.690 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr5_+_30666886 2.678 ENSMUST00000144742.1
Cenpa
centromere protein A
chr2_+_30061754 2.658 ENSMUST00000149578.1
ENSMUST00000102866.3
Set

SET nuclear oncogene

chr4_+_150236685 2.651 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr11_+_3289168 2.648 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr4_+_140700487 2.648 ENSMUST00000071169.2
Rcc2
regulator of chromosome condensation 2
chr2_-_181043540 2.645 ENSMUST00000124400.1
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr2_+_163661495 2.614 ENSMUST00000135537.1
Pkig
protein kinase inhibitor, gamma
chr4_-_133872997 2.589 ENSMUST00000137486.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr15_-_78803015 2.588 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr7_-_143074561 2.561 ENSMUST00000148715.1
Trpm5
transient receptor potential cation channel, subfamily M, member 5
chr9_-_99876147 2.544 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr13_-_18382041 2.538 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr6_+_125552948 2.520 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr9_+_66946057 2.518 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr14_+_24490678 2.515 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr8_-_83741169 2.511 ENSMUST00000075843.6
ENSMUST00000109802.2
ENSMUST00000002964.7
ENSMUST00000166939.1
Cd97



CD97 antigen



chr10_+_63061582 2.482 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr11_-_100356116 2.466 ENSMUST00000138603.2
Hap1
huntingtin-associated protein 1
chr12_-_40038025 2.450 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr1_-_184883218 2.415 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr3_-_83789956 2.414 ENSMUST00000180472.1
Gm26771
predicted gene, 26771
chr8_-_45382198 2.398 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr6_-_128437653 2.378 ENSMUST00000151796.1
Fkbp4
FK506 binding protein 4
chr1_+_134962553 2.366 ENSMUST00000027687.7
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr3_-_9004472 2.350 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr11_-_4095344 2.341 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr3_+_137341103 2.336 ENSMUST00000119475.1
Emcn
endomucin
chr3_-_106014630 2.326 ENSMUST00000010280.4
Pifo
primary cilia formation
chr8_+_106683052 2.317 ENSMUST00000048359.4
Tango6
transport and golgi organization 6
chr9_-_119339989 2.301 ENSMUST00000035092.6
Myd88
myeloid differentiation primary response gene 88
chr1_-_63176653 2.299 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr4_-_55532453 2.297 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr16_+_18348181 2.278 ENSMUST00000115614.2
ENSMUST00000115613.1
ENSMUST00000090103.3
Arvcf


armadillo repeat gene deleted in velo-cardio-facial syndrome


chr8_-_122611419 2.263 ENSMUST00000015171.9
Galns
galactosamine (N-acetyl)-6-sulfate sulfatase
chrX_-_73930751 2.261 ENSMUST00000155597.1
ENSMUST00000114379.1
Renbp

renin binding protein

chr4_-_116708312 2.233 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr2_+_121295437 2.224 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr4_+_116708571 2.212 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr15_+_83526854 2.209 ENSMUST00000016902.3
Bik
BCL2-interacting killer
chr3_-_49757257 2.189 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr7_+_28440927 2.188 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr16_-_33967032 2.147 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr10_-_9675163 2.110 ENSMUST00000100070.2
Samd5
sterile alpha motif domain containing 5
chr6_+_91978851 2.110 ENSMUST00000089334.2
Fgd5
FYVE, RhoGEF and PH domain containing 5
chr5_-_136883115 2.103 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1

collagen, type XXVI, alpha 1

chr5_+_138363719 2.102 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr4_-_118437331 2.091 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr11_+_115603920 2.090 ENSMUST00000058109.8
Mrps7
mitchondrial ribosomal protein S7
chr10_-_24927444 2.089 ENSMUST00000020161.8
Arg1
arginase, liver
chr11_-_17211504 2.064 ENSMUST00000020317.7
Pno1
partner of NOB1 homolog (S. cerevisiae)
chr1_-_153332724 2.048 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr11_-_35834492 2.046 ENSMUST00000018992.3
Rars
arginyl-tRNA synthetase
chr3_-_95015214 2.043 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
Zfp687


zinc finger protein 687


chr11_+_32286946 2.041 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr4_-_129227883 2.037 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr12_+_69168808 2.036 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr14_+_57798620 2.026 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr17_-_25844417 2.020 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr10_+_117629493 2.019 ENSMUST00000020399.5
Cpm
carboxypeptidase M
chr10_-_61383523 2.012 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr17_+_35424842 1.997 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr5_+_130219706 1.995 ENSMUST00000065329.6
Tmem248
transmembrane protein 248
chr7_-_45136231 1.994 ENSMUST00000124300.1
ENSMUST00000085377.5
Rpl13a
Flt3l
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr11_-_100356078 1.981 ENSMUST00000103124.4
Hap1
huntingtin-associated protein 1
chr6_-_53820764 1.971 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr15_+_89075996 1.960 ENSMUST00000081702.5
Trabd
TraB domain containing
chr19_-_46045194 1.955 ENSMUST00000156585.1
ENSMUST00000152946.1
Ldb1

LIM domain binding 1

chrX_+_159372175 1.944 ENSMUST00000087143.6
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
chr14_+_67716262 1.944 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr5_+_120116480 1.935 ENSMUST00000031590.8
Rbm19
RNA binding motif protein 19
chr9_-_21963568 1.931 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr3_-_9004422 1.929 ENSMUST00000063496.7
Tpd52
tumor protein D52
chr2_-_32288022 1.923 ENSMUST00000183946.1
ENSMUST00000113400.2
ENSMUST00000050410.4
Swi5


SWI5 recombination repair homolog (yeast)


chr9_+_89199319 1.923 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr15_+_78899755 1.922 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1


SH3-domain binding protein 1


chr6_+_127233756 1.917 ENSMUST00000071458.3
Gm4968
predicted gene 4968
chr8_+_84946987 1.913 ENSMUST00000067472.7
ENSMUST00000109740.2
Rtbdn

retbindin

chr6_-_69243445 1.909 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr10_+_94576254 1.907 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr8_-_70523085 1.890 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
Kxd1



KxDL motif containing 1



chr5_-_122697603 1.888 ENSMUST00000071235.4
Gm10064
predicted gene 10064
chr1_+_4807823 1.860 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
Lypla1




lysophospholipase 1




chr11_-_78536235 1.846 ENSMUST00000017759.2
ENSMUST00000108277.2
Tnfaip1

tumor necrosis factor, alpha-induced protein 1 (endothelial)

chr14_+_57798637 1.845 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr11_-_70982987 1.841 ENSMUST00000078528.6
C1qbp
complement component 1, q subcomponent binding protein
chr15_+_89076124 1.839 ENSMUST00000165690.1
Trabd
TraB domain containing
chr1_+_34439851 1.817 ENSMUST00000027303.7
Imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr11_-_117873433 1.811 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr11_+_117308135 1.804 ENSMUST00000153668.1
Sept9
septin 9
chr12_+_75308308 1.792 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr10_+_83360206 1.790 ENSMUST00000020488.7
D10Wsu102e
DNA segment, Chr 10, Wayne State University 102, expressed
chr1_+_86064619 1.775 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr4_+_95579463 1.768 ENSMUST00000150830.1
ENSMUST00000134012.2
Fggy

FGGY carbohydrate kinase domain containing

chr1_-_75180349 1.766 ENSMUST00000027396.8
Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr15_+_89076058 1.761 ENSMUST00000169891.1
Trabd
TraB domain containing
chr4_-_132075250 1.759 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr5_+_149439706 1.759 ENSMUST00000031667.4
Tex26
testis expressed 26
chr9_-_45936049 1.756 ENSMUST00000034590.2
Tagln
transgelin
chr4_-_150909812 1.752 ENSMUST00000134751.1
ENSMUST00000030805.7
Park7

Parkinson disease (autosomal recessive, early onset) 7

chr3_+_121291725 1.751 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr14_-_57398483 1.748 ENSMUST00000022517.7
Cryl1
crystallin, lambda 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
4.7 18.8 GO:0032439 endosome localization(GO:0032439)
4.1 16.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.6 7.8 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
2.5 7.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.5 7.4 GO:0016115 terpenoid catabolic process(GO:0016115)
2.4 7.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
2.3 7.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
2.3 7.0 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
2.3 9.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
2.3 6.9 GO:0018298 protein-chromophore linkage(GO:0018298)
2.0 5.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.8 5.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.7 8.6 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.7 11.9 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.7 5.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.5 4.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.3 4.0 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.3 3.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.3 3.8 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.3 3.8 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.2 6.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
1.2 3.6 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.1 4.4 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.1 3.2 GO:0006657 CDP-choline pathway(GO:0006657)
1.1 3.2 GO:0006083 acetate metabolic process(GO:0006083)
1.0 6.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.0 9.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.0 2.9 GO:0046061 dATP catabolic process(GO:0046061)
0.9 6.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.9 3.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.9 4.5 GO:0030091 protein repair(GO:0030091)
0.9 9.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 2.7 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.9 15.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.9 2.6 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.9 2.6 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.8 2.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.8 3.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.8 9.6 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.8 2.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.7 5.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.7 2.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.7 2.1 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
0.7 1.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.7 2.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.7 2.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.6 1.3 GO:0035106 operant conditioning(GO:0035106)
0.6 3.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.6 1.8 GO:0006566 threonine metabolic process(GO:0006566)
0.6 1.8 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
0.6 1.7 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.6 2.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.5 1.6 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.5 1.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 3.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.5 2.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.5 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 1.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 10.9 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.5 2.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 1.5 GO:1903998 regulation of eating behavior(GO:1903998)
0.5 1.9 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.5 2.9 GO:0008343 adult feeding behavior(GO:0008343)
0.5 1.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 1.9 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.5 8.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.5 2.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.5 1.4 GO:2000620 programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 1.8 GO:0015886 heme transport(GO:0015886)
0.4 2.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 0.8 GO:0036166 phenotypic switching(GO:0036166)
0.4 1.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.4 1.5 GO:0015793 glycerol transport(GO:0015793)
0.4 1.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.9 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.4 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.4 4.7 GO:0043589 skin morphogenesis(GO:0043589)
0.4 1.4 GO:0018343 protein farnesylation(GO:0018343)
0.3 3.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 4.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 1.6 GO:0031033 myosin filament organization(GO:0031033)
0.3 1.0 GO:0014012 negative regulation of Schwann cell proliferation(GO:0010626) peripheral nervous system axon regeneration(GO:0014012)
0.3 0.9 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.3 2.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.3 0.3 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.3 7.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.3 1.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 1.7 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.3 10.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 0.8 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 0.8 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 1.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.3 1.0 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 4.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 5.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.0 GO:0071865 regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.2 1.7 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.2 1.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 0.7 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 0.7 GO:0002176 male germ cell proliferation(GO:0002176)
0.2 0.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 2.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 3.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 0.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.9 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.2 1.9 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2 2.8 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.2 0.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 0.6 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 2.7 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.6 GO:0032055 negative regulation of translation in response to stress(GO:0032055) positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 1.2 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.9 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 2.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 1.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 1.9 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 1.6 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 0.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.9 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 2.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 4.9 GO:0001706 endoderm formation(GO:0001706)
0.1 0.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.7 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 3.0 GO:0032094 response to food(GO:0032094)
0.1 0.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 2.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 3.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 2.3 GO:0050909 sensory perception of taste(GO:0050909)
0.1 2.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.0 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 3.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.3 GO:0060539 diaphragm development(GO:0060539)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 5.1 GO:0043039 tRNA aminoacylation(GO:0043039)
0.1 0.7 GO:0001302 replicative cell aging(GO:0001302)
0.1 1.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 2.0 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.7 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 1.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.7 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 1.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.9 GO:0043687 post-translational protein modification(GO:0043687)
0.1 2.4 GO:0000154 rRNA modification(GO:0000154)
0.1 0.8 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.8 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 1.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 1.1 GO:0051225 spindle assembly(GO:0051225)
0.1 3.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.2 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.1 0.9 GO:0060179 male mating behavior(GO:0060179)
0.1 2.3 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.9 GO:0021559 trigeminal nerve development(GO:0021559)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 10.3 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.1 0.1 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.1 0.3 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.1 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.1 0.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 2.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 3.3 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.1 1.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.6 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 1.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.7 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 1.1 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1 0.7 GO:0097049 motor neuron apoptotic process(GO:0097049) regulation of motor neuron apoptotic process(GO:2000671)
0.1 1.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 3.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.8 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.1 1.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 1.7 GO:0006413 translational initiation(GO:0006413)
0.1 0.8 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 0.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.5 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.1 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.1 3.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.7 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 1.6 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 1.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.9 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 7.2 GO:0051099 positive regulation of binding(GO:0051099)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 6.7 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.0 2.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.9 GO:0048536 spleen development(GO:0048536)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.4 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 2.5 GO:0030168 platelet activation(GO:0030168)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.3 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.5 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 2.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 1.0 GO:0045471 response to ethanol(GO:0045471)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 1.9 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 1.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.7 GO:0006364 rRNA processing(GO:0006364)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 1.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.7 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.5 GO:0060021 palate development(GO:0060021)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.5 GO:0006417 regulation of translation(GO:0006417)
0.0 0.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of sulfur metabolic process(GO:0042762) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0048524 positive regulation of viral process(GO:0048524)
0.0 0.2 GO:1901984 negative regulation of protein acetylation(GO:1901984)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 1.6 GO:0045333 cellular respiration(GO:0045333)
0.0 0.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:0032648 regulation of interferon-beta production(GO:0032648)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 21.2 GO:0061689 tricellular tight junction(GO:0061689)
3.1 18.8 GO:0045179 apical cortex(GO:0045179)
2.6 18.5 GO:0097452 GAIT complex(GO:0097452)
2.0 5.9 GO:0005588 collagen type V trimer(GO:0005588)
1.6 4.7 GO:0005584 collagen type I trimer(GO:0005584)
1.4 7.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.3 18.1 GO:0035686 sperm fibrous sheath(GO:0035686)
1.3 16.7 GO:0042612 MHC class I protein complex(GO:0042612)
1.3 6.3 GO:0033093 Weibel-Palade body(GO:0033093)
1.2 7.3 GO:0030896 checkpoint clamp complex(GO:0030896)
1.0 2.9 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.6 3.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 5.0 GO:0042611 MHC protein complex(GO:0042611)
0.6 3.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.6 1.8 GO:0034457 Mpp10 complex(GO:0034457)
0.6 5.4 GO:0061574 ASAP complex(GO:0061574)
0.5 3.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.5 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.5 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.5 2.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.5 4.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.5 1.8 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.4 3.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 3.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 3.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.4 1.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.4 1.1 GO:0071920 cleavage body(GO:0071920)
0.4 3.2 GO:0042587 glycogen granule(GO:0042587)
0.3 1.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 2.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3 1.5 GO:0072487 MSL complex(GO:0072487)
0.3 2.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 0.9 GO:0000814 ESCRT II complex(GO:0000814)
0.3 0.8 GO:0031417 NatC complex(GO:0031417)
0.3 1.9 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.3 0.8 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 2.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 2.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 2.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 16.4 GO:0005581 collagen trimer(GO:0005581)
0.2 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 16.7 GO:0005643 nuclear pore(GO:0005643)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 8.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.6 GO:0000793 condensed chromosome(GO:0000793)
0.2 1.8 GO:0031105 septin complex(GO:0031105)
0.1 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 8.8 GO:0005871 kinesin complex(GO:0005871)
0.1 11.0 GO:0014704 intercalated disc(GO:0014704)
0.1 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 1.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 1.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.0 GO:0089701 U2AF(GO:0089701)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.3 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.8 GO:0001650 fibrillar center(GO:0001650)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0000801 central element(GO:0000801)
0.1 5.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 5.1 GO:0016234 inclusion body(GO:0016234)
0.1 2.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.4 GO:0032433 filopodium tip(GO:0032433)
0.1 1.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.2 GO:0030120 vesicle coat(GO:0030120)
0.1 1.4 GO:0070069 cytochrome complex(GO:0070069)
0.1 3.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 3.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 4.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.8 GO:0005770 late endosome(GO:0005770)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 9.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 3.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 4.5 GO:0005840 ribosome(GO:0005840)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 9.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 13.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0031514 motile cilium(GO:0031514)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 14.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.2 GO:0001726 ruffle(GO:0001726)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.1 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
2.6 7.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.6 7.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
2.3 6.9 GO:0009881 photoreceptor activity(GO:0009881)
2.2 8.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.9 9.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.8 5.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.7 9.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.4 7.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.3 4.0 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.3 3.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.2 7.4 GO:0019841 retinol binding(GO:0019841)
1.2 20.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.1 3.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.1 7.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.0 2.9 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.0 4.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.9 5.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.9 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.9 1.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.8 3.3 GO:0070976 TIR domain binding(GO:0070976)
0.8 7.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.7 10.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.7 10.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 2.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
0.7 3.3 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 4.5 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.6 3.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 10.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.6 1.8 GO:0030519 snoRNP binding(GO:0030519)
0.6 1.8 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.6 1.8 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
0.6 6.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.6 1.7 GO:0047598 7-dehydrocholesterol reductase activity(GO:0047598)
0.6 4.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 1.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.5 1.6 GO:0070052 collagen V binding(GO:0070052)
0.5 3.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.5 2.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.5 1.4 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.5 1.4 GO:0048045 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.5 1.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.5 1.8 GO:0030984 kininogen binding(GO:0030984)
0.5 5.9 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.4 5.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 2.5 GO:0008494 translation activator activity(GO:0008494)
0.4 9.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 1.6 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.4 1.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.4 3.7 GO:0030274 LIM domain binding(GO:0030274)
0.4 1.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 2.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 2.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.4 GO:0002054 nucleobase binding(GO:0002054)
0.3 1.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.3 3.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 2.2 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.3 1.2 GO:1990460 leptin receptor binding(GO:1990460)
0.3 3.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.3 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 2.6 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.3 1.6 GO:0043176 amine binding(GO:0043176)
0.3 4.2 GO:0042605 peptide antigen binding(GO:0042605)
0.3 1.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.3 2.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 2.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 3.4 GO:0005537 mannose binding(GO:0005537)
0.2 2.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 2.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 0.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 4.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 27.8 GO:0003774 motor activity(GO:0003774)
0.2 1.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 3.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 3.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 1.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 3.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 2.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.7 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 3.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 2.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 0.5 GO:0019002 GMP binding(GO:0019002)
0.2 0.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 2.2 GO:0051400 BH domain binding(GO:0051400)
0.2 3.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.9 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.3 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 4.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 8.1 GO:0000049 tRNA binding(GO:0000049)
0.1 1.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 4.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 2.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 2.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 3.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 3.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 4.5 GO:0030332 cyclin binding(GO:0030332)
0.1 1.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.0 GO:0032564 dATP binding(GO:0032564)
0.1 1.7 GO:0005542 folic acid binding(GO:0005542)
0.1 4.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 3.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.7 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 2.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.3 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.0 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.1 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.4 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 7.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 12.8 GO:0003729 mRNA binding(GO:0003729)
0.1 0.5 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.6 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0039706 phosphatase activator activity(GO:0019211) co-receptor binding(GO:0039706)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0031078 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.7 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 2.6 GO:0046332 SMAD binding(GO:0046332)
0.0 2.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 5.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 17.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 5.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0035326 enhancer binding(GO:0035326)
0.0 0.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 3.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.9 GO:0046982 protein heterodimerization activity(GO:0046982)