Motif ID: Esrrg
Z-value: 0.385
Transcription factors associated with Esrrg:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Esrrg | ENSMUSG00000026610.7 | Esrrg |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Esrrg | mm10_v2_chr1_+_187609028_187609047 | 0.11 | 4.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.8 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 1.4 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.3 | 0.8 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.3 | 0.8 | GO:0006533 | aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
| 0.2 | 0.6 | GO:0042713 | negative regulation of urine volume(GO:0035811) sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455) |
| 0.2 | 1.9 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.2 | 0.5 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
| 0.2 | 0.8 | GO:0014719 | skeletal muscle satellite cell activation(GO:0014719) |
| 0.1 | 0.5 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.1 | 0.4 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 0.1 | 0.4 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.1 | 0.5 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.1 | 0.6 | GO:1901524 | regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
| 0.1 | 0.5 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.1 | 0.4 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.1 | 0.6 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 0.2 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.1 | 0.7 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 0.9 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
| 0.1 | 0.3 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.1 | 0.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 1.0 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 0.2 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.1 | 0.4 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.1 | 0.2 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.0 | 0.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.1 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
| 0.0 | 0.2 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.0 | 0.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.0 | 0.2 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 0.3 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.0 | 0.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.3 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 0.1 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
| 0.0 | 0.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.1 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 0.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.0 | 0.4 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 0.6 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.2 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.1 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.0 | 0.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.0 | 0.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.2 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.0 | 0.1 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
| 0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.3 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.0 | 0.6 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 0.6 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.2 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 1.2 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 0.4 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.0 | 0.3 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.0 | 0.1 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.0 | 0.2 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.5 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.2 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.1 | GO:0051764 | actin crosslink formation(GO:0051764) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.2 | 1.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.2 | 0.9 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 3.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 0.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 0.5 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.1 | 0.2 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.2 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.2 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.0 | 0.3 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.0 | 0.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.4 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.8 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 1.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.1 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.0 | 0.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.0 | 0.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 1.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.4 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.1 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.6 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.4 | GO:0032040 | small-subunit processome(GO:0032040) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.9 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.3 | 0.8 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.2 | 1.0 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.2 | 1.4 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.2 | 0.9 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.2 | 0.5 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 0.1 | 0.4 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.1 | 0.5 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 1.4 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 0.2 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.1 | 2.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 0.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.3 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.1 | 1.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.2 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.1 | 0.2 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 0.2 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.1 | 0.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.3 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 0.3 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 0.8 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.0 | 0.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.4 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.0 | 0.3 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.0 | 0.2 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.5 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 0.2 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.1 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.2 | GO:0035925 | translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.1 | GO:0004017 | adenylate kinase activity(GO:0004017) |
