Motif ID: Esrrg

Z-value: 0.385


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187609028_1876090470.114.0e-01Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 190 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_107517321 1.437 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr18_+_77185815 1.248 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr16_+_32608973 1.174 ENSMUST00000120680.1
 Tfrc
transferrin receptor
chr8_+_70863127 1.074 ENSMUST00000050921.2
 A230052G05Rik
RIKEN cDNA A230052G05 gene
chr4_-_82505707 1.025 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr18_+_45268876 0.993 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr7_-_81706905 0.919 ENSMUST00000026922.7
 Homer2
homer homolog 2 (Drosophila)
chr4_-_82505274 0.891 ENSMUST00000050872.8
ENSMUST00000064770.2
 Nfib

nuclear factor I/B

chr4_-_82505749 0.867 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr12_+_61523889 0.866 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr18_+_57142782 0.776 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr19_-_43524462 0.773 ENSMUST00000026196.7
 Got1
glutamate oxaloacetate transaminase 1, soluble
chr16_+_32608920 0.769 ENSMUST00000023486.8
 Tfrc
transferrin receptor
chr12_-_84194007 0.732 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr5_+_123343834 0.725 ENSMUST00000120593.1
 Bcl7a
B cell CLL/lymphoma 7A
chr10_-_84440591 0.699 ENSMUST00000020220.8
 Nuak1
NUAK family, SNF1-like kinase, 1
chr7_-_37772868 0.691 ENSMUST00000176205.1
 Zfp536
zinc finger protein 536
chr4_+_13751297 0.661 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_29965560 0.634 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
 Sptan1





spectrin alpha, non-erythrocytic 1





chr11_-_97573929 0.631 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.9 GO:0033572 transferrin transport(GO:0033572)
0.3 1.4 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 1.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 1.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.9 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.3 0.8 GO:0009644 response to high light intensity(GO:0009644)
0.3 0.8 GO:0006533 aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.2 0.8 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 0.6 GO:0042713 negative regulation of urine volume(GO:0035811) sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.1 0.6 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.2 0.5 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.1 0.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.6 GO:0032437 cuticular plate(GO:0032437)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.2 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 1.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 1.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 0.8 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.8 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)