Motif ID: Ets1

Z-value: 0.727


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_32696121-0.142.8e-01Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 7.500 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr6_+_5725639 7.331 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 5.733 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr7_+_44850393 5.564 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr2_-_156312470 5.321 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr2_-_156392829 4.292 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr8_-_71723308 4.038 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr15_-_66812593 3.928 ENSMUST00000100572.3
Sla
src-like adaptor
chr3_-_89245159 3.743 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr3_-_89245005 3.576 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr18_-_34931931 3.440 ENSMUST00000180351.1
Etf1
eukaryotic translation termination factor 1
chr14_-_19977249 3.401 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr5_+_111733924 3.148 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr10_+_3366125 3.024 ENSMUST00000043374.5
Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr3_-_80802789 2.959 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr7_-_4546567 2.944 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr2_+_156312299 2.905 ENSMUST00000037096.2
Cnbd2
cyclic nucleotide binding domain containing 2
chr1_-_56969827 2.892 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_+_136713444 2.848 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr3_+_28263205 2.775 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 359 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.3 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.3 10.3 GO:0060074 synapse maturation(GO:0060074)
0.8 7.8 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 7.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 5.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.2 4.7 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2 4.3 GO:0002076 osteoblast development(GO:0002076)
0.2 4.1 GO:0006266 DNA ligation(GO:0006266)
0.2 4.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 3.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 3.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 3.4 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.2 3.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 3.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.6 3.0 GO:1900453 negative regulation of long term synaptic depression(GO:1900453)
0.6 3.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.5 3.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 3.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
1.0 2.9 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.7 2.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 13.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 12.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 7.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 7.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.2 GO:0005776 autophagosome(GO:0005776)
0.5 6.0 GO:0031931 TORC1 complex(GO:0031931)
0.3 5.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 4.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.1 4.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 4.2 GO:0030018 Z disc(GO:0030018)
0.0 4.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.4 3.6 GO:0071439 clathrin complex(GO:0071439)
0.0 3.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.3 GO:0070469 respiratory chain(GO:0070469)
0.5 3.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.7 2.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 207 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 13.1 GO:0045503 dynein light chain binding(GO:0045503)
0.2 9.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.5 8.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 7.8 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 5.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 5.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 5.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 5.2 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) phospholipase C activity(GO:0004629) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3 4.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 4.3 GO:0008565 protein transporter activity(GO:0008565)
0.1 4.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 3.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 3.4 GO:0030552 cAMP binding(GO:0030552)
0.2 3.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.4 3.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.2 3.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)