Motif ID: Ets2
Z-value: 1.368
Transcription factors associated with Ets2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Ets2 | ENSMUSG00000022895.8 | Ets2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ets2 | mm10_v2_chr16_+_95702044_95702094 | 0.29 | 2.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 7.6 | GO:0019085 | early viral transcription(GO:0019085) |
1.9 | 3.7 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
1.5 | 5.9 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
1.5 | 14.6 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
1.3 | 11.9 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
1.3 | 3.8 | GO:0019043 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) |
1.2 | 10.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
1.2 | 8.1 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
1.1 | 18.3 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
1.1 | 6.6 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
1.0 | 6.3 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) |
1.0 | 3.1 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
1.0 | 3.9 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
1.0 | 4.8 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.9 | 9.3 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.9 | 3.5 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
0.9 | 3.4 | GO:0018307 | enzyme active site formation(GO:0018307) |
0.8 | 2.5 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.8 | 3.2 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.8 | 4.0 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
0.8 | 3.2 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
0.8 | 0.8 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
0.8 | 2.3 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.8 | 3.8 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.7 | 6.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.7 | 4.4 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
0.7 | 2.1 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
0.7 | 33.5 | GO:0047496 | vesicle transport along microtubule(GO:0047496) |
0.7 | 3.5 | GO:0015871 | choline transport(GO:0015871) regulation of resting membrane potential(GO:0060075) |
0.7 | 2.0 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
0.6 | 5.1 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
0.6 | 3.1 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.6 | 1.8 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
0.6 | 2.4 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.6 | 4.7 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.6 | 1.7 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.6 | 1.7 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
0.5 | 2.7 | GO:0042117 | monocyte activation(GO:0042117) |
0.5 | 2.2 | GO:0070425 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
0.5 | 9.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.5 | 8.3 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.5 | 3.0 | GO:0048102 | autophagic cell death(GO:0048102) |
0.5 | 2.0 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.5 | 23.7 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.5 | 1.5 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
0.5 | 2.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.4 | 7.6 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.4 | 3.0 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.4 | 5.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.4 | 3.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.4 | 4.7 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.4 | 3.1 | GO:0097460 | ferrous iron import into cell(GO:0097460) |
0.4 | 4.5 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.4 | 1.9 | GO:0070166 | enamel mineralization(GO:0070166) |
0.4 | 1.1 | GO:0070488 | neutrophil aggregation(GO:0070488) |
0.4 | 13.0 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.4 | 6.8 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.4 | 1.1 | GO:0006624 | vacuolar protein processing(GO:0006624) |
0.4 | 1.4 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.4 | 2.1 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
0.3 | 5.4 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.3 | 4.6 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.3 | 10.2 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.3 | 2.6 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.3 | 1.2 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.3 | 0.9 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.3 | 2.3 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.3 | 2.7 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.3 | 1.6 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.3 | 1.3 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.3 | 1.1 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
0.3 | 0.8 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.3 | 1.0 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
0.3 | 2.6 | GO:1904152 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.3 | 5.6 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
0.3 | 1.8 | GO:0023035 | CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039) |
0.2 | 2.9 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.2 | 1.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.2 | 2.6 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.2 | 5.2 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.2 | 0.9 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
0.2 | 1.1 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.2 | 0.7 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.2 | 2.5 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.2 | 3.3 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
0.2 | 5.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.2 | 41.1 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.2 | 1.2 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.2 | 9.6 | GO:0015914 | phospholipid transport(GO:0015914) |
0.2 | 10.2 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.2 | 3.3 | GO:2000505 | regulation of energy homeostasis(GO:2000505) |
0.2 | 0.7 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.2 | 0.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.2 | 4.0 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.2 | 1.9 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
0.2 | 0.8 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.2 | 4.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.2 | 0.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.2 | 2.6 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.2 | 0.3 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.1 | 7.8 | GO:1902850 | mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850) |
0.1 | 0.7 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
0.1 | 1.3 | GO:0046415 | urate metabolic process(GO:0046415) |
0.1 | 1.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 10.0 | GO:0060976 | coronary vasculature development(GO:0060976) |
0.1 | 2.2 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
0.1 | 1.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.8 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 2.3 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
0.1 | 2.4 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.1 | 0.5 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 1.4 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.1 | 1.4 | GO:1902287 | semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
0.1 | 0.9 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 3.1 | GO:0007032 | endosome organization(GO:0007032) |
0.1 | 0.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.1 | 2.0 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.1 | 1.7 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.1 | 1.0 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
0.1 | 5.8 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
0.1 | 2.7 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.1 | 2.5 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
0.1 | 1.3 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.1 | 0.6 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.1 | 0.9 | GO:0051352 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
0.1 | 0.3 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
0.1 | 0.4 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
0.1 | 3.1 | GO:1901998 | toxin transport(GO:1901998) |
0.1 | 0.8 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
0.1 | 2.9 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
0.1 | 4.2 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.1 | GO:0019086 | late viral transcription(GO:0019086) |
0.1 | 0.3 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
0.1 | 1.3 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.1 | 1.7 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
0.1 | 3.1 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.1 | 0.2 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
0.1 | 1.3 | GO:0008210 | estrogen metabolic process(GO:0008210) |
0.1 | 0.3 | GO:0015867 | ATP transport(GO:0015867) |
0.1 | 0.3 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.1 | 2.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.1 | 1.5 | GO:0034629 | cellular protein complex localization(GO:0034629) |
0.1 | 0.5 | GO:0044804 | nucleophagy(GO:0044804) |
0.1 | 0.5 | GO:0006903 | vesicle targeting(GO:0006903) |
0.1 | 1.1 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.1 | 5.3 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.1 | 0.4 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.0 | 5.8 | GO:0030010 | establishment of cell polarity(GO:0030010) |
0.0 | 2.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 11.7 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
0.0 | 0.4 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
0.0 | 0.7 | GO:0006677 | glycosylceramide metabolic process(GO:0006677) |
0.0 | 4.9 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 2.6 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.0 | 1.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.6 | GO:1901655 | cellular response to ketone(GO:1901655) |
0.0 | 0.6 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
0.0 | 0.7 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.0 | 0.6 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 3.4 | GO:0031123 | RNA 3'-end processing(GO:0031123) |
0.0 | 0.3 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.0 | 1.8 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
0.0 | 1.4 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 2.2 | GO:0045665 | negative regulation of neuron differentiation(GO:0045665) |
0.0 | 0.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
0.0 | 0.3 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
0.0 | 0.7 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
0.0 | 0.4 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.0 | 3.3 | GO:0051262 | protein tetramerization(GO:0051262) |
0.0 | 2.0 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.5 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 1.4 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
0.0 | 3.5 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.0 | 1.1 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
0.0 | 0.2 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 1.7 | GO:0000209 | protein polyubiquitination(GO:0000209) |
0.0 | 0.7 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.1 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.2 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
0.0 | 0.4 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.2 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.0 | 0.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.2 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.0 | 0.9 | GO:0006986 | response to unfolded protein(GO:0006986) |
0.0 | 2.0 | GO:0051402 | neuron apoptotic process(GO:0051402) |
0.0 | 0.1 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
1.3 | 7.8 | GO:0000235 | astral microtubule(GO:0000235) |
1.2 | 3.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
1.2 | 32.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
1.1 | 10.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
1.1 | 10.6 | GO:0071439 | clathrin complex(GO:0071439) |
1.0 | 8.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.9 | 6.3 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
0.8 | 2.5 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.8 | 9.3 | GO:0031931 | TORC1 complex(GO:0031931) |
0.8 | 2.4 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.7 | 2.0 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.7 | 4.7 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.7 | 10.0 | GO:0031045 | dense core granule(GO:0031045) |
0.5 | 4.3 | GO:0032584 | growth cone membrane(GO:0032584) |
0.5 | 1.6 | GO:0036501 | UFD1-NPL4 complex(GO:0036501) |
0.5 | 6.0 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.5 | 11.9 | GO:0031430 | M band(GO:0031430) |
0.5 | 9.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.4 | 1.8 | GO:0071797 | LUBAC complex(GO:0071797) |
0.4 | 14.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.4 | 2.6 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.4 | 2.6 | GO:0070847 | core mediator complex(GO:0070847) |
0.4 | 15.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.4 | 2.7 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.4 | 2.7 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.4 | 3.1 | GO:0097433 | dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712) |
0.4 | 2.3 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.4 | 2.8 | GO:0005774 | vacuolar membrane(GO:0005774) |
0.4 | 7.7 | GO:0030673 | axolemma(GO:0030673) |
0.3 | 4.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.3 | 20.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.3 | 20.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.3 | 2.2 | GO:0030056 | hemidesmosome(GO:0030056) |
0.3 | 2.3 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.3 | 1.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.2 | 2.5 | GO:0005869 | dynactin complex(GO:0005869) |
0.2 | 2.1 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.2 | 1.6 | GO:0070695 | FHF complex(GO:0070695) |
0.2 | 6.2 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.2 | 2.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.2 | 2.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.2 | 0.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.2 | 0.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.2 | 15.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.2 | 1.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.2 | 0.5 | GO:0042585 | germinal vesicle(GO:0042585) |
0.2 | 2.3 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.2 | 3.5 | GO:0034451 | centriolar satellite(GO:0034451) |
0.2 | 1.7 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 1.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.1 | 5.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.9 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.1 | 5.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.1 | 0.5 | GO:0097441 | basilar dendrite(GO:0097441) |
0.1 | 2.2 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.5 | GO:0097361 | CIA complex(GO:0097361) |
0.1 | 1.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 1.0 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.1 | 0.4 | GO:0072487 | MSL complex(GO:0072487) |
0.1 | 1.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.1 | 2.3 | GO:0030904 | retromer complex(GO:0030904) |
0.1 | 10.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 0.8 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 5.9 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 0.4 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 1.0 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 7.9 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.1 | 0.9 | GO:0001527 | microfibril(GO:0001527) |
0.1 | 1.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.7 | GO:0071203 | WASH complex(GO:0071203) |
0.1 | 2.3 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 2.0 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.1 | 3.5 | GO:0014704 | intercalated disc(GO:0014704) |
0.1 | 3.5 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.1 | 0.5 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.1 | 1.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 4.4 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
0.0 | 5.1 | GO:0031514 | motile cilium(GO:0031514) |
0.0 | 3.9 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.0 | 1.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.5 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 11.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
0.0 | 5.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 0.2 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 0.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.5 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 2.7 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 3.4 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 1.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.2 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 2.7 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 6.3 | GO:0005768 | endosome(GO:0005768) |
0.0 | 2.2 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 1.0 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.5 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.6 | 32.9 | GO:0045503 | dynein light chain binding(GO:0045503) |
1.9 | 9.5 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
1.6 | 9.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.8 | 4.0 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.7 | 2.2 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.7 | 3.5 | GO:0086080 | connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.7 | 6.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.7 | 2.8 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.7 | 4.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.7 | 3.4 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.6 | 16.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.6 | 2.3 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.6 | 2.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
0.5 | 2.2 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
0.5 | 2.7 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.5 | 3.1 | GO:0070728 | leucine binding(GO:0070728) |
0.5 | 2.5 | GO:0019961 | interferon binding(GO:0019961) |
0.5 | 18.0 | GO:0045296 | cadherin binding(GO:0045296) |
0.5 | 11.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.5 | 1.4 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.4 | 3.1 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.4 | 6.7 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.4 | 1.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.4 | 1.2 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
0.4 | 11.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.4 | 21.2 | GO:0030276 | clathrin binding(GO:0030276) |
0.4 | 3.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.4 | 7.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.4 | 1.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.4 | 1.1 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.4 | 10.2 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.3 | 5.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.3 | 1.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.3 | 4.8 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.3 | 1.2 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.3 | 1.5 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
0.3 | 1.7 | GO:0016936 | galactoside binding(GO:0016936) |
0.3 | 1.6 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.3 | 1.0 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
0.3 | 0.8 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.3 | 5.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.3 | 2.3 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.2 | 3.5 | GO:0008430 | selenium binding(GO:0008430) |
0.2 | 29.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.2 | 0.7 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.2 | 1.7 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
0.2 | 2.9 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.2 | 3.0 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.2 | 25.4 | GO:0008565 | protein transporter activity(GO:0008565) |
0.2 | 9.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.2 | 0.6 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.2 | 0.7 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
0.2 | 1.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.2 | 6.4 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.1 | 3.1 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.1 | 0.7 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.1 | 1.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.1 | 1.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 2.2 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
0.1 | 1.5 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 1.7 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 6.3 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.1 | 4.8 | GO:0045502 | dynein binding(GO:0045502) |
0.1 | 2.8 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 1.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 2.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 1.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.1 | 0.9 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.1 | 0.3 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
0.1 | 1.1 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.1 | 0.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 2.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.1 | 1.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 0.3 | GO:0015217 | ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.1 | 2.5 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.1 | 4.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 2.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 1.4 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.1 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 1.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.1 | 2.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 11.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.1 | 2.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.1 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 1.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 1.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 5.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.1 | 9.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.1 | 0.6 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
0.1 | 0.5 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 1.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.1 | 0.7 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 2.6 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.1 | 1.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 4.3 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.1 | 1.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 3.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.1 | 2.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 1.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 5.7 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.1 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 17.0 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.1 | 3.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.1 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.0 | 5.6 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.0 | 0.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.4 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) |
0.0 | 2.8 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
0.0 | 1.9 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 7.1 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 1.4 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.1 | GO:0000339 | RNA cap binding(GO:0000339) |
0.0 | 0.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 2.3 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.0 | 1.9 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.7 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 2.2 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.0 | 2.6 | GO:0044389 | ubiquitin-like protein ligase binding(GO:0044389) |
0.0 | 0.2 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
0.0 | 0.7 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.1 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.4 | GO:0005158 | insulin receptor binding(GO:0005158) |