Motif ID: Etv1_Etv5_Gabpa

Z-value: 1.934

Transcription factors associated with Etv1_Etv5_Gabpa:

Gene SymbolEntrez IDGene Name
Etv1 ENSMUSG00000004151.10 Etv1
Etv5 ENSMUSG00000013089.9 Etv5
Gabpa ENSMUSG00000008976.10 Gabpa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv5mm10_v2_chr16_-_22439719_22439733-0.652.7e-08Click!
Etv1mm10_v2_chr12_+_38783503_38783527-0.591.0e-06Click!
Gabpamm10_v2_chr16_+_84835070_84835124-0.454.0e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Etv1_Etv5_Gabpa

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_57836706 19.208 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr16_-_22161450 17.277 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_5845243 16.947 ENSMUST00000127116.1
Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_-_94653964 16.708 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_+_5845017 12.922 ENSMUST00000026927.3
ENSMUST00000179748.1
Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr7_-_126792469 12.742 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr6_+_4755327 12.691 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr4_+_124714776 12.017 ENSMUST00000030734.4
Sf3a3
splicing factor 3a, subunit 3
chr14_-_31494992 11.448 ENSMUST00000055303.3
Mettl6
methyltransferase like 6
chr4_-_45320580 11.227 ENSMUST00000030003.3
Exosc3
exosome component 3
chr2_-_130179310 10.901 ENSMUST00000103199.4
Snrpb
small nuclear ribonucleoprotein B
chr5_+_140331860 10.608 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr12_+_100110148 10.482 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr4_+_118409331 10.293 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr11_+_101733011 10.045 ENSMUST00000129741.1
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr3_+_87930256 9.981 ENSMUST00000055984.6
Isg20l2
interferon stimulated exonuclease gene 20-like 2
chr3_-_129831374 9.971 ENSMUST00000029643.8
Gar1
GAR1 ribonucleoprotein homolog (yeast)
chr2_+_74825802 9.914 ENSMUST00000028511.7
Mtx2
metaxin 2
chr5_+_149184648 9.646 ENSMUST00000122160.1
ENSMUST00000100410.3
ENSMUST00000119685.1
Uspl1


ubiquitin specific peptidase like 1


chr17_-_29264115 9.634 ENSMUST00000024802.8
Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 712 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 127.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
1.9 72.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.6 63.0 GO:0006413 translational initiation(GO:0006413)
0.6 52.9 GO:0042254 ribosome biogenesis(GO:0042254)
1.6 50.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
1.2 46.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.8 45.3 GO:0051028 mRNA transport(GO:0051028)
2.0 39.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.5 39.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.7 32.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
2.2 30.6 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 29.5 GO:0006412 translation(GO:0006412)
2.6 28.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.8 28.0 GO:0002181 cytoplasmic translation(GO:0002181)
3.3 26.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
6.5 26.0 GO:0030576 Cajal body organization(GO:0030576)
1.4 24.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.4 23.9 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.6 23.9 GO:0032543 mitochondrial translation(GO:0032543)
0.3 23.3 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 316 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 144.9 GO:0005730 nucleolus(GO:0005730)
1.7 127.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.3 103.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
1.8 90.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
4.3 52.0 GO:0005687 U4 snRNP(GO:0005687)
0.1 41.1 GO:0005667 transcription factor complex(GO:0005667)
1.2 40.7 GO:0030684 preribosome(GO:0030684)
0.4 39.0 GO:0005681 spliceosomal complex(GO:0005681)
1.2 38.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
3.8 38.0 GO:0031595 nuclear proteasome complex(GO:0031595)
1.1 37.9 GO:0015030 Cajal body(GO:0015030)
0.6 32.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.4 27.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
3.3 26.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 25.8 GO:0005643 nuclear pore(GO:0005643)
0.6 25.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.2 24.3 GO:0031080 nuclear pore outer ring(GO:0031080)
1.6 22.4 GO:0000974 Prp19 complex(GO:0000974)
0.5 22.1 GO:0008180 COP9 signalosome(GO:0008180)
1.4 21.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 419 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 209.1 GO:0044822 poly(A) RNA binding(GO:0044822)
0.8 164.0 GO:0003735 structural constituent of ribosome(GO:0003735)
1.3 82.9 GO:0003743 translation initiation factor activity(GO:0003743)
1.1 63.4 GO:0019843 rRNA binding(GO:0019843)
0.7 43.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 42.9 GO:0003723 RNA binding(GO:0003723)
1.7 41.2 GO:0030515 snoRNA binding(GO:0030515)
4.2 33.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.4 32.8 GO:0008173 RNA methyltransferase activity(GO:0008173)
1.0 31.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
4.0 28.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.3 27.9 GO:0017025 TBP-class protein binding(GO:0017025)
8.7 26.0 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
2.4 26.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 26.0 GO:0000049 tRNA binding(GO:0000049)
0.6 25.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.4 24.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
3.3 23.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 22.2 GO:0004519 endonuclease activity(GO:0004519)
2.7 21.9 GO:0003688 DNA replication origin binding(GO:0003688)