Motif ID: Etv3_Erf_Fev_Elk4_Elk1_Elk3

Z-value: 0.911


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elk1mm10_v2_chrX_-_20950597_209506130.841.7e-16Click!
Erfmm10_v2_chr7_-_25250720_25250761-0.604.1e-07Click!
Elk4mm10_v2_chr1_+_132007606_1320076340.401.9e-03Click!
Etv3mm10_v2_chr3_+_87525572_875256430.085.3e-01Click!
Elk3mm10_v2_chr10_-_93311073_933111610.028.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Etv3_Erf_Fev_Elk4_Elk1_Elk3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156392829 10.208 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr2_-_156312470 9.104 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr2_+_163602331 8.592 ENSMUST00000152135.1
Ttpal
tocopherol (alpha) transfer protein-like
chr2_+_168230597 7.834 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr17_+_35135174 7.589 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chr7_-_4546567 7.416 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr17_+_35135196 7.384 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr6_+_8259288 7.347 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr5_-_3803081 7.229 ENSMUST00000043551.6
Ankib1
ankyrin repeat and IBR domain containing 1
chr8_-_69791170 7.227 ENSMUST00000131784.1
Zfp866
zinc finger protein 866
chr11_-_48817332 7.028 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr7_+_122067164 6.989 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr9_-_29411736 6.956 ENSMUST00000115236.1
Ntm
neurotrimin
chr9_-_18473559 6.910 ENSMUST00000034647.4
Zfp558
zinc finger protein 558
chr7_+_44850393 6.773 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr11_+_6200029 6.615 ENSMUST00000181545.1
A730071L15Rik
RIKEN cDNA A730071L15Rik gene
chr12_-_84970814 6.522 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr2_+_91650116 6.468 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr2_-_73312701 6.409 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr17_+_33955902 6.384 ENSMUST00000173196.2
Vps52
vacuolar protein sorting 52 (yeast)

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 402 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 24.0 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 16.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 15.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 14.7 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.2 13.2 GO:0003281 ventricular septum development(GO:0003281)
4.1 12.2 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.8 12.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.0 11.3 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.5 10.7 GO:0030033 microvillus assembly(GO:0030033)
0.2 9.6 GO:0048278 vesicle docking(GO:0048278)
0.4 9.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 9.2 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.4 8.7 GO:0002076 osteoblast development(GO:0002076)
0.1 8.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.3 8.2 GO:0006829 zinc II ion transport(GO:0006829)
2.6 7.8 GO:0019085 early viral transcription(GO:0019085)
2.0 7.8 GO:0018307 enzyme active site formation(GO:0018307)
0.6 6.6 GO:0030157 pancreatic juice secretion(GO:0030157)
0.2 6.5 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 6.5 GO:0006897 endocytosis(GO:0006897)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 174 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 24.3 GO:0030131 clathrin adaptor complex(GO:0030131)
3.4 24.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 19.8 GO:0005794 Golgi apparatus(GO:0005794)
0.6 18.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
3.1 15.7 GO:1990745 EARP complex(GO:1990745)
0.3 13.7 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
1.2 13.4 GO:0031931 TORC1 complex(GO:0031931)
0.1 12.9 GO:0005802 trans-Golgi network(GO:0005802)
0.2 12.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 12.3 GO:0005769 early endosome(GO:0005769)
1.5 12.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.3 11.3 GO:0032807 DNA ligase IV complex(GO:0032807)
1.0 10.4 GO:0071439 clathrin complex(GO:0071439)
0.1 10.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 9.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 8.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 8.4 GO:0031225 anchored component of membrane(GO:0031225)
1.3 8.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 7.6 GO:0031594 neuromuscular junction(GO:0031594)
0.5 7.4 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 251 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 39.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.3 25.7 GO:0070628 proteasome binding(GO:0070628)
0.2 20.5 GO:0008565 protein transporter activity(GO:0008565)
0.3 18.5 GO:0030276 clathrin binding(GO:0030276)
0.1 17.1 GO:0017124 SH3 domain binding(GO:0017124)
0.2 16.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 16.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 11.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.7 10.8 GO:0070300 phosphatidic acid binding(GO:0070300)
2.1 10.7 GO:0071253 connexin binding(GO:0071253)
0.3 10.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.5 9.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 8.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
1.6 7.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 7.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 7.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.4 7.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 6.9 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989)
0.3 6.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 6.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)