Motif ID: Fos

Z-value: 0.829


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_854738960.057.1e-01Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_82910863 8.296 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr13_+_15463837 7.187 ENSMUST00000110510.3
 Gli3
GLI-Kruppel family member GLI3
chr7_-_126799163 7.051 ENSMUST00000032934.5
 Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126799134 6.746 ENSMUST00000087566.4
 Aldoa
aldolase A, fructose-bisphosphate
chr2_+_30078584 5.978 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chrX_-_143827391 5.515 ENSMUST00000087316.5
 Capn6
calpain 6
chr10_+_88091070 5.155 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr2_+_13573927 5.122 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr6_+_53573364 5.005 ENSMUST00000047450.7
 Creb5
cAMP responsive element binding protein 5
chr18_+_35118880 4.928 ENSMUST00000042345.6
 Ctnna1
catenin (cadherin associated protein), alpha 1
chrX_+_96455359 4.840 ENSMUST00000033553.7
 Heph
hephaestin
chr16_-_44558864 4.702 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chrX_+_164269371 4.640 ENSMUST00000145412.1
ENSMUST00000033749.7
 Pir

pirin

chr7_+_128523576 4.631 ENSMUST00000033136.7
 Bag3
BCL2-associated athanogene 3
chr10_-_42583628 4.511 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr5_+_42067960 4.451 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr9_+_78615501 4.302 ENSMUST00000093812.4
 Cd109
CD109 antigen
chr11_-_102365111 4.158 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr16_-_44558879 4.158 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr2_+_91257323 4.078 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 13.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 8.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 8.3 GO:0009409 response to cold(GO:0009409)
2.4 7.2 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.9 5.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 5.5 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 5.5 GO:0001578 microtubule bundle formation(GO:0001578)
1.7 5.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 5.2 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
1.0 5.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 5.0 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.2 4.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 4.8 GO:0006825 copper ion transport(GO:0006825)
0.2 4.6 GO:0030224 monocyte differentiation(GO:0030224)
0.2 4.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 4.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.9 4.5 GO:0021764 amygdala development(GO:0021764)
0.0 4.4 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.0 4.4 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
1.1 4.3 GO:0072675 osteoclast fusion(GO:0072675)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 13.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 12.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 7.1 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 6.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.2 6.7 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.5 GO:0016592 mediator complex(GO:0016592)
0.1 5.5 GO:0005876 spindle microtubule(GO:0005876)
1.3 5.1 GO:0045098 type III intermediate filament(GO:0045098)
0.4 4.9 GO:0005915 zonula adherens(GO:0005915)
0.3 4.3 GO:0031932 TORC2 complex(GO:0031932)
1.4 4.2 GO:1990047 spindle matrix(GO:1990047)
0.1 4.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 4.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 3.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.5 GO:0031519 PcG protein complex(GO:0031519)
0.3 3.3 GO:0031105 septin complex(GO:0031105)
0.0 3.3 GO:0010008 endosome membrane(GO:0010008)
0.2 3.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 13.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 12.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 12.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 8.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 7.0 GO:0017166 vinculin binding(GO:0017166)
0.3 6.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 6.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 6.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 6.2 GO:0003924 GTPase activity(GO:0003924)
0.0 6.1 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.2 6.0 GO:0004697 protein kinase C activity(GO:0004697)
0.4 5.7 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 5.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.8 5.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 4.9 GO:1990254 keratin filament binding(GO:1990254)
0.0 4.9 GO:0003779 actin binding(GO:0003779)
1.0 4.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 4.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 4.8 GO:0001671 ATPase activator activity(GO:0001671)
0.8 4.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)