Motif ID: Fosb

Z-value: 0.439


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.444.9e-04Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

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Top targets:


Showing 1 to 20 of 88 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_118663235 3.088 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_+_27622433 2.489 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr4_+_42158092 2.157 ENSMUST00000098122.2
 Gm13306
predicted gene 13306
chr6_-_124769548 2.155 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr3_+_55461758 2.152 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr10_+_26078255 1.861 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr1_-_12991109 1.848 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr14_+_80000292 1.827 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr8_-_8639363 1.780 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr11_-_100397740 1.764 ENSMUST00000001592.8
ENSMUST00000107403.1
 Jup

junction plakoglobin

chr1_+_134560157 1.723 ENSMUST00000047714.7
 Kdm5b
lysine (K)-specific demethylase 5B
chr9_+_104566677 1.712 ENSMUST00000157006.1
 Cpne4
copine IV
chr11_-_84067063 1.697 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr1_+_134560190 1.689 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr2_+_167777467 1.432 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr16_-_4880284 1.285 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr15_+_102503722 1.275 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr2_+_156475844 1.212 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr7_-_4778141 1.146 ENSMUST00000094892.5
 Il11
interleukin 11
chr4_-_140774196 1.134 ENSMUST00000026381.6
 Padi4
peptidyl arginine deiminase, type IV

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.4 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.0 3.1 GO:0007613 memory(GO:0007613)
0.1 2.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 2.2 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.1 1.9 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.6 1.8 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.8 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 1.1 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 1.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 1.1 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 1.0 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 1.0 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.8 GO:0048840 otolith development(GO:0048840)
0.0 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0048786 presynaptic active zone(GO:0048786)
0.4 2.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.0 1.0 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0045095 keratin filament(GO:0045095)
0.2 0.5 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 3.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.2 2.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 1.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.8 GO:0045296 cadherin binding(GO:0045296)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.1 GO:0043531 ADP binding(GO:0043531)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125) growth factor activity(GO:0008083)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.6 GO:0003998 acylphosphatase activity(GO:0003998)