Motif ID: Fosl2_Bach2
Z-value: 0.891
Transcription factors associated with Fosl2_Bach2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bach2 | ENSMUSG00000040270.10 | Bach2 |
Fosl2 | ENSMUSG00000029135.9 | Fosl2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Fosl2 | mm10_v2_chr5_+_32136458_32136505 | 0.73 | 4.4e-11 | Click! |
Bach2 | mm10_v2_chr4_+_32238950_32238964 | 0.30 | 2.2e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 11.1 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
2.2 | 8.7 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
1.9 | 11.3 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) |
1.9 | 5.6 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
1.8 | 7.2 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
1.3 | 3.9 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
1.3 | 7.6 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
1.2 | 4.7 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
1.1 | 12.6 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
1.0 | 3.9 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.9 | 8.7 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.9 | 6.8 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.8 | 5.0 | GO:0046103 | ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103) |
0.8 | 1.6 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
0.7 | 2.7 | GO:0070885 | negative regulation of interleukin-17 production(GO:0032700) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) cellular response to copper ion(GO:0071280) |
0.7 | 5.2 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.6 | 5.8 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
0.6 | 2.6 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
0.6 | 3.8 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.6 | 1.9 | GO:0086017 | Purkinje myocyte action potential(GO:0086017) |
0.6 | 4.1 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
0.6 | 1.7 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
0.6 | 2.8 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122) |
0.6 | 1.7 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.6 | 0.6 | GO:0030397 | membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) |
0.5 | 5.6 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
0.5 | 3.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.5 | 1.5 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.5 | 1.9 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.5 | 0.5 | GO:0030862 | regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
0.5 | 1.8 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.4 | 1.3 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.4 | 1.3 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
0.4 | 4.1 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
0.4 | 1.6 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.4 | 5.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.4 | 14.0 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.4 | 1.5 | GO:1901524 | regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
0.4 | 2.2 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) phospholipid efflux(GO:0033700) |
0.4 | 1.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
0.3 | 1.4 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.3 | 1.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.3 | 2.5 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.3 | 0.9 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
0.3 | 0.9 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
0.3 | 1.5 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.3 | 2.9 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.3 | 3.8 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
0.3 | 3.6 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.3 | 1.3 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.3 | 4.4 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.2 | 1.2 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.2 | 2.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 1.9 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.2 | 0.6 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.2 | 13.8 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.2 | 3.9 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
0.2 | 1.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.2 | 2.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.2 | 7.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.2 | 0.2 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.2 | 1.4 | GO:0007296 | vitellogenesis(GO:0007296) |
0.2 | 0.6 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.2 | 0.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.2 | 0.7 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.2 | 2.8 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
0.2 | 0.3 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.2 | 1.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.2 | 1.1 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.1 | 0.7 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
0.1 | 0.4 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.1 | 0.7 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.1 | 2.5 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.1 | 2.5 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
0.1 | 1.5 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.1 | 0.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.6 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.1 | 0.9 | GO:0015862 | uridine transport(GO:0015862) |
0.1 | 3.6 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 0.4 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
0.1 | 4.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.1 | 4.9 | GO:1902668 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668) |
0.1 | 0.6 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 1.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 1.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.1 | 1.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.1 | 3.9 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 0.5 | GO:0060763 | mammary duct terminal end bud growth(GO:0060763) |
0.1 | 1.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 0.7 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.1 | 1.0 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 2.6 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.1 | 2.3 | GO:0042058 | regulation of epidermal growth factor receptor signaling pathway(GO:0042058) |
0.1 | 0.3 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.1 | 1.4 | GO:0032060 | bleb assembly(GO:0032060) |
0.1 | 0.5 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.1 | 6.0 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.1 | 1.9 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.1 | 5.0 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.1 | 0.9 | GO:0060742 | prostate gland growth(GO:0060736) epithelial cell differentiation involved in prostate gland development(GO:0060742) |
0.1 | 1.6 | GO:0033198 | response to ATP(GO:0033198) |
0.1 | 0.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.1 | 0.6 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.1 | 0.2 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 0.3 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
0.1 | 0.6 | GO:0044804 | nucleophagy(GO:0044804) |
0.1 | 1.3 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.1 | 2.0 | GO:0060325 | face morphogenesis(GO:0060325) |
0.1 | 0.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 0.9 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
0.1 | 1.0 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.1 | 2.4 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
0.1 | 0.2 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.1 | 0.5 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.1 | 0.2 | GO:0045713 | low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) |
0.1 | 0.4 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.1 | 0.2 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.1 | 0.6 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
0.0 | 0.4 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 3.4 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.0 | 0.7 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.0 | 0.2 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.0 | 0.8 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.0 | 1.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.0 | 0.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 1.2 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.2 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 1.4 | GO:0051438 | regulation of ubiquitin-protein transferase activity(GO:0051438) |
0.0 | 0.2 | GO:0001675 | acrosome assembly(GO:0001675) |
0.0 | 4.3 | GO:0006275 | regulation of DNA replication(GO:0006275) |
0.0 | 0.3 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.0 | 0.2 | GO:1904587 | glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587) |
0.0 | 0.3 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.0 | 0.7 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.5 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.1 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
0.0 | 0.1 | GO:0019532 | oxalate transport(GO:0019532) |
0.0 | 0.1 | GO:0031442 | positive regulation of mRNA 3'-end processing(GO:0031442) |
0.0 | 2.1 | GO:0043523 | regulation of neuron apoptotic process(GO:0043523) |
0.0 | 0.3 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.0 | 0.3 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.2 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 2.9 | GO:0006417 | regulation of translation(GO:0006417) |
0.0 | 0.7 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 7.2 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
1.6 | 11.3 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
1.6 | 11.1 | GO:0005638 | lamin filament(GO:0005638) |
1.1 | 12.4 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
1.1 | 5.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
1.1 | 4.2 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
1.0 | 3.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.8 | 2.5 | GO:0044754 | amphisome(GO:0044753) autolysosome(GO:0044754) |
0.8 | 2.5 | GO:0005927 | muscle tendon junction(GO:0005927) |
0.7 | 2.9 | GO:0031673 | H zone(GO:0031673) |
0.6 | 2.6 | GO:1990795 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
0.6 | 5.0 | GO:0001520 | outer dense fiber(GO:0001520) |
0.5 | 1.6 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
0.5 | 1.4 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.5 | 2.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.4 | 2.5 | GO:0097513 | myosin II filament(GO:0097513) |
0.4 | 2.6 | GO:0016461 | unconventional myosin complex(GO:0016461) |
0.3 | 4.8 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.3 | 21.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.3 | 1.5 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.2 | 1.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.2 | 1.5 | GO:0005883 | neurofilament(GO:0005883) |
0.2 | 6.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.2 | 6.7 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.6 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.1 | 1.6 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 1.9 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.1 | 6.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 9.7 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 1.0 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.1 | 1.4 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.1 | 3.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 5.3 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.1 | 0.9 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 1.6 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.1 | 5.1 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 0.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.1 | 0.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.6 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.0 | 4.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.4 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 0.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 7.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.6 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 7.6 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 7.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 3.9 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 1.3 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 2.3 | GO:0005901 | caveola(GO:0005901) |
0.0 | 3.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 2.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 1.6 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 1.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 2.6 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 2.7 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 1.0 | GO:0005844 | polysome(GO:0005844) |
0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.4 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 1.5 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 1.2 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 2.2 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 0.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 10.2 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
1.4 | 12.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
1.3 | 3.9 | GO:0051379 | epinephrine binding(GO:0051379) |
1.1 | 6.8 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.9 | 7.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.8 | 1.5 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.7 | 5.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.6 | 5.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.6 | 3.9 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.5 | 2.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.5 | 11.3 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.5 | 1.5 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
0.5 | 5.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.5 | 1.8 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.4 | 1.3 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.4 | 14.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.4 | 11.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.4 | 1.6 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
0.4 | 8.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.3 | 1.7 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.3 | 1.3 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.3 | 2.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.3 | 0.9 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.3 | 1.7 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.3 | 6.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.3 | 1.6 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.3 | 8.2 | GO:0042805 | actinin binding(GO:0042805) |
0.3 | 2.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.3 | 1.9 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.3 | 4.1 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.3 | 4.6 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.2 | 0.7 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
0.2 | 2.7 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.2 | 8.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.2 | 0.9 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.2 | 1.4 | GO:0070728 | leucine binding(GO:0070728) |
0.2 | 0.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.2 | 2.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.2 | 5.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.2 | 3.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.2 | 3.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.2 | 1.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.2 | 4.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.2 | 3.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.2 | 3.1 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.2 | 0.6 | GO:0004942 | anaphylatoxin receptor activity(GO:0004942) |
0.2 | 1.1 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.2 | 2.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.2 | 3.9 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.2 | 1.0 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.2 | 1.0 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.2 | 0.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.2 | 2.8 | GO:0001968 | fibronectin binding(GO:0001968) |
0.2 | 2.0 | GO:0016443 | bidentate ribonuclease III activity(GO:0016443) |
0.1 | 0.4 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.1 | 5.7 | GO:0043531 | ADP binding(GO:0043531) |
0.1 | 1.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.6 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
0.1 | 4.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 9.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.1 | 1.0 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 7.9 | GO:0005518 | collagen binding(GO:0005518) |
0.1 | 0.9 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.5 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.1 | 1.6 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.1 | 0.7 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.1 | 1.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 1.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.1 | 2.0 | GO:0003785 | actin monomer binding(GO:0003785) |
0.1 | 0.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 7.7 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.1 | 0.7 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 4.5 | GO:0017022 | myosin binding(GO:0017022) |
0.1 | 1.0 | GO:0043236 | laminin binding(GO:0043236) |
0.1 | 8.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 0.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 1.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.1 | 0.5 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.1 | 1.0 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.1 | 0.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 0.6 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.1 | 0.3 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.1 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.1 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.1 | 0.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 1.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.2 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.0 | 2.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.9 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 0.8 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 2.3 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.1 | GO:0003883 | CTP synthase activity(GO:0003883) |
0.0 | 1.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 4.3 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 1.9 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.3 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.1 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.2 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.0 | 2.7 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 2.1 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.7 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 2.9 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.0 | 1.6 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 3.6 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.2 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.4 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 1.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.7 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |