Motif ID: Foxa3

Z-value: 1.120


Transcription factors associated with Foxa3:

Gene SymbolEntrez IDGene Name
Foxa3 ENSMUSG00000040891.5 Foxa3



Activity profile for motif Foxa3.

activity profile for motif Foxa3


Sorted Z-values histogram for motif Foxa3

Sorted Z-values for motif Foxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxa3

PNG image of the network

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Top targets:


Showing 1 to 20 of 153 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 18.550 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr7_-_103813913 13.209 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr7_-_103827922 9.818 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr15_+_3270767 9.384 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_+_113765998 9.205 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr1_+_51289106 8.487 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr15_-_54919961 7.633 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr10_+_60106452 7.081 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr7_+_113766119 6.316 ENSMUST00000084696.4
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr15_-_54920115 6.144 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_+_78499087 5.355 ENSMUST00000017488.4
 Vtn
vitronectin
chr17_+_70522083 4.995 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr2_-_84425258 4.371 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr9_-_103222063 3.790 ENSMUST00000170904.1
 Trf
transferrin
chr17_+_70522149 3.775 ENSMUST00000140728.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr6_-_137571007 3.640 ENSMUST00000100841.2
 Eps8
epidermal growth factor receptor pathway substrate 8
chr4_+_45965327 3.621 ENSMUST00000107777.2
 Tdrd7
tudor domain containing 7
chr16_+_41532851 3.612 ENSMUST00000078873.4
 Lsamp
limbic system-associated membrane protein
chr3_-_87263518 3.474 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr12_-_84450944 3.428 ENSMUST00000085192.5
 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 16.1 GO:0048663 neuron fate commitment(GO:0048663)
2.0 13.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.3 9.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.7 8.8 GO:0070842 aggresome assembly(GO:0070842)
0.8 7.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 5.4 GO:0097421 liver regeneration(GO:0097421)
0.0 4.5 GO:0051028 mRNA transport(GO:0051028)
1.1 4.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 4.2 GO:0034605 cellular response to heat(GO:0034605)
0.5 3.8 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.9 3.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 3.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 3.6 GO:0035641 locomotory exploration behavior(GO:0035641)
1.1 3.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.7 3.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 3.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 3.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 3.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.4 2.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 2.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.8 23.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 22.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 20.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 11.1 GO:0005615 extracellular space(GO:0005615)
0.1 8.5 GO:0005901 caveola(GO:0005901)
0.0 8.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 6.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
1.1 5.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 4.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 3.8 GO:0097433 dense body(GO:0097433)
0.5 3.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 3.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 3.4 GO:0031965 nuclear membrane(GO:0031965)
0.1 3.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.5 GO:0005768 endosome(GO:0005768)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.8 23.0 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
3.4 13.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.6 9.4 GO:0008430 selenium binding(GO:0008430)
0.3 8.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 7.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 5.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.1 4.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 4.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 4.0 GO:0005516 calmodulin binding(GO:0005516)
0.5 3.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 3.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 3.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 3.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.9 2.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)