Motif ID: Foxd2

Z-value: 0.926


Transcription factors associated with Foxd2:

Gene SymbolEntrez IDGene Name
Foxd2 ENSMUSG00000055210.3 Foxd2



Activity profile for motif Foxd2.

activity profile for motif Foxd2


Sorted Z-values histogram for motif Foxd2

Sorted Z-values for motif Foxd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 98 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_104114088 12.691 ENSMUST00000031249.3
 Sparcl1
SPARC-like 1
chr18_+_37504264 11.915 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr14_+_101840602 7.413 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr3_+_89520152 6.906 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_+_43508118 6.326 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr14_-_30353468 6.267 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr14_+_101840501 5.841 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr15_+_92597104 5.381 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr7_-_61982348 5.263 ENSMUST00000181804.1
ENSMUST00000181187.1
 A330076H08Rik

RIKEN cDNA A330076H08 gene

chr10_+_67096456 5.240 ENSMUST00000174317.1
 Jmjd1c
jumonji domain containing 1C
chr2_-_45110336 5.061 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr18_+_37513652 4.978 ENSMUST00000061405.4
 Pcdhb21
protocadherin beta 21
chrX_-_105929206 4.793 ENSMUST00000134381.1
ENSMUST00000154866.1
 Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr4_-_14621805 4.683 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chrX_-_105929333 4.637 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
 Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr3_+_76075583 4.320 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr7_-_61982290 4.313 ENSMUST00000180481.1
 A330076H08Rik
RIKEN cDNA A330076H08 gene
chr14_+_80000292 4.166 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr4_-_136898803 4.144 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr6_+_13069758 4.034 ENSMUST00000124234.1
ENSMUST00000142211.1
ENSMUST00000031556.7
 Tmem106b


transmembrane protein 106B



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 13.1 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 9.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 7.4 GO:0016337 single organismal cell-cell adhesion(GO:0016337)
2.1 6.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 5.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 5.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.7 5.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.8 5.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.7 5.1 GO:0019532 oxalate transport(GO:0019532)
0.1 4.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 4.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 4.0 GO:0032418 lysosome localization(GO:0032418)
0.4 3.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.6 3.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 3.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 3.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.5 2.7 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 2.7 GO:0046541 saliva secretion(GO:0046541)
0.6 2.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 2.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 13.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 12.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 12.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 9.7 GO:0030175 filopodium(GO:0030175)
0.0 6.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.6 6.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 4.2 GO:0042581 specific granule(GO:0042581)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.0 3.9 GO:0030426 growth cone(GO:0030426)
0.2 3.7 GO:0071564 npBAF complex(GO:0071564)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 3.4 GO:0030139 endocytic vesicle(GO:0030139)
0.9 2.7 GO:0043512 inhibin A complex(GO:0043512)
0.1 2.7 GO:0043034 costamere(GO:0043034)
0.0 2.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 2.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.9 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 13.3 GO:0042805 actinin binding(GO:0042805)
1.9 13.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 12.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 9.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.7 6.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.0 6.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 6.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 5.2 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.5 5.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 5.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 4.2 GO:0045296 cadherin binding(GO:0045296)
0.1 3.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 3.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.5 2.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 2.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.6 GO:0005521 lamin binding(GO:0005521)
0.0 2.5 GO:0005179 hormone activity(GO:0005179)