Motif ID: Foxf2

Z-value: 0.885


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_31625816-0.038.0e-01Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 98 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 20.081 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr8_-_84773381 14.767 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr6_-_148444336 9.994 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr4_+_101507947 8.443 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 7.391 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_-_4844665 6.259 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr16_-_4880284 5.646 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr7_+_45783883 5.222 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_45783686 5.098 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr12_-_112511136 4.867 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr7_+_44849581 4.840 ENSMUST00000150335.1
ENSMUST00000107882.1
 Akt1s1

AKT1 substrate 1 (proline-rich)

chr10_+_60106452 4.589 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr7_+_82175156 4.586 ENSMUST00000180243.1
 Sh3gl3
SH3-domain GRB2-like 3
chr1_+_179546303 4.386 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr5_+_88583527 4.103 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr14_-_51913393 3.975 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chrX_+_163911401 3.869 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_42229726 3.797 ENSMUST00000066196.1
 Gm9915
predicted gene 9915
chr16_-_34263179 3.788 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr17_+_70522083 3.781 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 20.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
2.6 15.8 GO:0072318 clathrin coat disassembly(GO:0072318)
1.1 14.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 13.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 11.5 GO:0006396 RNA processing(GO:0006396)
0.1 10.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 6.5 GO:0070842 aggresome assembly(GO:0070842)
1.1 6.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.8 6.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 6.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 6.1 GO:0007379 segment specification(GO:0007379)
0.5 4.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.5 4.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.2 4.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 4.0 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.1 3.9 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 3.7 GO:0050919 negative chemotaxis(GO:0050919)
0.1 3.6 GO:0050729 positive regulation of inflammatory response(GO:0050729)
1.1 3.2 GO:0002159 desmosome assembly(GO:0002159)
0.2 3.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 30.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.8 26.5 GO:0055038 recycling endosome membrane(GO:0055038)
1.0 11.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 6.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 6.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 5.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.6 GO:0005769 early endosome(GO:0005769)
0.6 4.1 GO:0071437 invadopodium(GO:0071437)
0.0 3.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 3.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.2 GO:0032590 dendrite membrane(GO:0032590)
0.7 2.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 1.5 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.4 1.5 GO:0031673 H zone(GO:0031673)
0.0 1.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 0.7 GO:0005712 chiasma(GO:0005712)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 23.3 GO:0045296 cadherin binding(GO:0045296)
0.1 15.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 7.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 6.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
1.3 6.4 GO:0097001 ceramide binding(GO:0097001)
0.0 5.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.9 4.4 GO:0071253 connexin binding(GO:0071253)
0.0 3.9 GO:0008565 protein transporter activity(GO:0008565)
0.5 2.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 2.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.6 GO:0070888 E-box binding(GO:0070888)
0.4 2.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.7 2.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.0 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 1.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)