Motif ID: Foxg1

Z-value: 0.476


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49383007_49383105-0.691.9e-09Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120476469 11.995 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr10_+_22158566 4.011 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr9_+_91378636 3.270 ENSMUST00000066384.5
Zic4
zinc finger protein of the cerebellum 4
chr13_-_71963713 3.173 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr12_-_10900296 2.821 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr13_-_3918157 2.771 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr18_-_34007206 2.311 ENSMUST00000025234.5
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr1_-_72874877 2.094 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr4_+_154960915 1.877 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_-_57124003 1.443 ENSMUST00000112629.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr7_-_115824699 1.253 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr11_-_89538556 1.189 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr4_-_108833544 1.083 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr15_-_85581809 0.947 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr10_-_24836165 0.868 ENSMUST00000020169.7
Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr6_-_72345144 0.844 ENSMUST00000070345.3
Usp39
ubiquitin specific peptidase 39
chr3_-_95015416 0.783 ENSMUST00000132195.1
Zfp687
zinc finger protein 687
chr12_-_104751900 0.759 ENSMUST00000041987.6
Dicer1
dicer 1, ribonuclease type III
chr3_-_95015214 0.752 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
Zfp687


zinc finger protein 687


chr9_+_64121501 0.751 ENSMUST00000118215.1
Lctl
lactase-like
chr5_+_34369909 0.685 ENSMUST00000180376.1
Fam193a
family with sequence similarity 193, member A
chr13_+_34162953 0.681 ENSMUST00000124996.1
ENSMUST00000147632.1
Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr5_-_134314678 0.649 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
Gtf2i







general transcription factor II I







chr1_-_84284423 0.605 ENSMUST00000176720.1
Pid1
phosphotyrosine interaction domain containing 1
chr11_+_72607221 0.578 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr6_-_129717132 0.556 ENSMUST00000088046.1
Klri1
killer cell lectin-like receptor family I member 1
chr16_-_90284412 0.552 ENSMUST00000039280.7
Scaf4
SR-related CTD-associated factor 4
chr5_+_145204523 0.544 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr4_-_108833608 0.541 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr16_-_90284300 0.486 ENSMUST00000163419.1
Scaf4
SR-related CTD-associated factor 4
chr19_+_11770415 0.461 ENSMUST00000167199.1
Mrpl16
mitochondrial ribosomal protein L16
chr9_+_106170918 0.425 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr11_+_3488275 0.424 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr2_+_174330006 0.404 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr9_-_60649793 0.385 ENSMUST00000053171.7
Lrrc49
leucine rich repeat containing 49
chr14_-_24245913 0.384 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chr16_-_28929658 0.383 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr2_-_164389095 0.378 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr5_-_121191365 0.373 ENSMUST00000100770.2
ENSMUST00000054547.7
Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr1_-_180813534 0.369 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr6_-_12109583 0.235 ENSMUST00000080891.5
Gm6578
predicted gene 6578
chr11_-_28583995 0.207 ENSMUST00000146385.2
Ccdc85a
coiled-coil domain containing 85A
chr1_-_180813591 0.128 ENSMUST00000162118.1
ENSMUST00000159685.1
ENSMUST00000161308.1
H3f3a


H3 histone, family 3A


chr18_-_68300329 0.088 ENSMUST00000042852.6
Fam210a
family with sequence similarity 210, member A
chr4_+_116720920 0.030 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2

testis-specific kinase 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 12.0 GO:0060613 fat pad development(GO:0060613)
0.5 1.9 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.4 1.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 0.9 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 2.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 0.8 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.2 0.6 GO:0090298 positive regulation of fat cell proliferation(GO:0070346) negative regulation of mitochondrial DNA replication(GO:0090298)
0.2 2.8 GO:0051451 myoblast migration(GO:0051451)
0.2 4.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 1.2 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.4 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.5 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 1.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.9 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 2.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 11.8 GO:0000785 chromatin(GO:0000785)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.0 GO:0003680 AT DNA binding(GO:0003680)
0.5 4.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 0.8 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 2.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.9 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)