Motif ID: Foxi1_Foxo1

Z-value: 2.304

Transcription factors associated with Foxi1_Foxo1:

Gene SymbolEntrez IDGene Name
Foxi1 ENSMUSG00000047861.2 Foxi1
Foxo1 ENSMUSG00000044167.5 Foxo1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo1mm10_v2_chr3_+_52268337_522683880.085.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxi1_Foxo1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 70.209 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr17_-_70851710 39.886 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr11_+_32276400 33.500 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr12_-_56535047 27.989 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr8_-_46294592 26.495 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr12_+_109452833 25.274 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr18_-_47333311 24.096 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr5_-_138170992 22.277 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_+_55741810 21.956 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr4_+_65124174 21.733 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chr11_-_102365111 21.357 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr17_+_47505117 21.056 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3

cyclin D3

chr3_+_134236483 19.465 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr17_+_47505149 19.103 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr7_-_37773555 19.084 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr9_+_78615501 18.881 ENSMUST00000093812.4
Cd109
CD109 antigen
chr5_-_138171248 18.460 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_+_47505043 18.080 ENSMUST00000182129.1
ENSMUST00000171031.1
Ccnd3

cyclin D3

chr16_-_22161450 18.003 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr3_-_52104891 17.392 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 504 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 74.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
11.7 70.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
4.1 53.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
10.0 50.2 GO:0015671 oxygen transport(GO:0015671)
5.5 49.7 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.9 42.0 GO:0006270 DNA replication initiation(GO:0006270)
2.3 41.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.1 40.3 GO:0038092 nodal signaling pathway(GO:0038092)
1.1 31.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
9.3 28.0 GO:0021759 globus pallidus development(GO:0021759)
1.0 24.9 GO:0007638 mechanosensory behavior(GO:0007638)
1.6 24.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
2.1 23.5 GO:0061032 visceral serous pericardium development(GO:0061032)
2.0 21.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.2 21.4 GO:0046685 response to arsenic-containing substance(GO:0046685)
7.1 21.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.7 20.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
6.5 19.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.1 19.0 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.2 18.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 217 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 138.7 GO:0005634 nucleus(GO:0005634)
0.3 95.2 GO:0005667 transcription factor complex(GO:0005667)
2.0 91.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
4.1 62.2 GO:0042555 MCM complex(GO:0042555)
0.3 62.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.6 48.9 GO:0005902 microvillus(GO:0005902)
6.0 47.7 GO:0005833 hemoglobin complex(GO:0005833)
7.8 38.9 GO:0097149 centralspindlin complex(GO:0097149)
4.2 38.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 32.1 GO:0072562 blood microparticle(GO:0072562)
0.1 31.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.3 28.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 28.4 GO:0000776 kinetochore(GO:0000776)
0.5 27.6 GO:0005871 kinesin complex(GO:0005871)
0.3 26.3 GO:0031513 nonmotile primary cilium(GO:0031513)
0.2 24.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 24.2 GO:0031225 anchored component of membrane(GO:0031225)
0.3 22.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 20.9 GO:0031012 extracellular matrix(GO:0031012)
0.6 19.9 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 364 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 112.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.5 68.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
1.3 66.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
2.2 57.0 GO:0008432 JUN kinase binding(GO:0008432)
10.0 50.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 43.7 GO:0051015 actin filament binding(GO:0051015)
1.3 37.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 33.0 GO:0005178 integrin binding(GO:0005178)
0.3 30.3 GO:0017048 Rho GTPase binding(GO:0017048)
1.2 30.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
2.4 29.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.8 27.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.1 26.5 GO:0030506 ankyrin binding(GO:0030506)
2.1 22.7 GO:0008517 folic acid transporter activity(GO:0008517)
1.0 21.9 GO:0017049 GTP-Rho binding(GO:0017049)
1.4 21.6 GO:0035198 miRNA binding(GO:0035198)
7.1 21.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.5 21.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 20.3 GO:0003677 DNA binding(GO:0003677)
0.3 19.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)