Motif ID: Foxk1_Foxj1

Z-value: 0.819

Transcription factors associated with Foxk1_Foxj1:

Gene SymbolEntrez IDGene Name
Foxj1 ENSMUSG00000034227.7 Foxj1
Foxk1 ENSMUSG00000056493.8 Foxk1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxk1mm10_v2_chr5_+_142401484_142401532-0.471.8e-04Click!
Foxj1mm10_v2_chr11_-_116335384_1163353990.229.7e-02Click!


Activity profile for motif Foxk1_Foxj1.

activity profile for motif Foxk1_Foxj1


Sorted Z-values histogram for motif Foxk1_Foxj1

Sorted Z-values for motif Foxk1_Foxj1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxk1_Foxj1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 5.097 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chrX_+_170010744 4.885 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chr19_-_34255325 3.156 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chrY_+_90785442 3.061 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr10_-_96409038 2.986 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr2_-_154769932 2.953 ENSMUST00000184654.1
 Gm14214
predicted gene 14214
chr15_+_99006056 2.856 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr14_-_62456286 2.410 ENSMUST00000165651.1
ENSMUST00000022501.3
 Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr16_-_36784924 2.199 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
 Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr12_-_4689926 2.083 ENSMUST00000080062.6
 Gm17541
predicted gene, 17541
chr10_-_37138863 1.969 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr14_+_11227511 1.933 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr3_+_159495408 1.920 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
 Depdc1a


DEP domain containing 1a


chr16_-_36784784 1.891 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr18_-_51865881 1.821 ENSMUST00000091905.2
 Gm4950
predicted pseudogene 4950
chr15_+_85116829 1.807 ENSMUST00000105085.1
 Gm10923
predicted gene 10923
chrY_+_1010543 1.790 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr4_-_55532453 1.650 ENSMUST00000132746.1
ENSMUST00000107619.2
 Klf4

Kruppel-like factor 4 (gut)

chr10_-_92165159 1.606 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr12_+_112999964 1.605 ENSMUST00000180971.1
 9230104M06Rik
RIKEN cDNA 9230104M06 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.0 4.1 GO:0042938 dipeptide transport(GO:0042938)
0.1 3.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 3.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 3.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 2.4 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.1 2.2 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.1 1.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.5 1.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 1.5 GO:0007405 neuroblast proliferation(GO:0007405)
0.2 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 1.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 1.2 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 1.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.3 1.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 1.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.3 1.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 3.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.7 2.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.8 GO:0070469 respiratory chain(GO:0070469)
0.1 1.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.1 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.4 3.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 2.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.7 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 1.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.3 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 1.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 0.9 GO:0016015 morphogen activity(GO:0016015)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)