Motif ID: Foxm1

Z-value: 0.681


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.191.5e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 150 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_65845833 4.758 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_-_138842429 4.105 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr2_+_65845767 3.882 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_34807287 3.374 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr16_-_23890805 2.644 ENSMUST00000004480.3
 Sst
somatostatin
chr15_+_98167806 2.610 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr12_-_56536895 2.122 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr1_-_79440039 1.939 ENSMUST00000049972.4
 Scg2
secretogranin II
chrX_-_141725181 1.922 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr18_+_37484955 1.909 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr10_+_127421208 1.823 ENSMUST00000168780.1
 R3hdm2
R3H domain containing 2
chr2_+_104095796 1.600 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr4_-_44710408 1.518 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
 Pax5









paired box gene 5









chr5_+_137553517 1.468 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
 Actl6b




actin-like 6B




chr10_-_81230773 1.411 ENSMUST00000047408.4
 Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr11_-_42000284 1.407 ENSMUST00000109292.2
ENSMUST00000109290.1
 Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr5_-_103211251 1.381 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
 Mapk10



mitogen-activated protein kinase 10



chr11_-_42000532 1.293 ENSMUST00000070735.3
 Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr10_+_127421124 1.276 ENSMUST00000170336.1
 R3hdm2
R3H domain containing 2
chr18_+_36952621 1.263 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.8 4.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 3.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 2.7 GO:0071420 cellular response to histamine(GO:0071420)
0.7 2.1 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.3 1.6 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 1.5 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 1.5 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.5 1.4 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 1.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 1.1 GO:0061055 myotome development(GO:0061055)
0.2 1.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 1.0 GO:0046898 response to cycloheximide(GO:0046898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 0.9 GO:0002177 manchette(GO:0002177)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 3.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.2 2.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.6 GO:0001848 complement binding(GO:0001848)
0.1 1.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)