Motif ID: Foxo4
Z-value: 1.014
Transcription factors associated with Foxo4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxo4 | ENSMUSG00000042903.7 | Foxo4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxo4 | mm10_v2_chrX_+_101254528_101254574 | 0.46 | 2.2e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 6.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 1.1 | 3.3 | GO:0045349 | regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 1.0 | 4.9 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.8 | 3.2 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.7 | 2.2 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.7 | 2.2 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.5 | 1.4 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.4 | 2.2 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.3 | 2.1 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.3 | 3.6 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.3 | 0.9 | GO:0032829 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) negative regulation of interleukin-2 biosynthetic process(GO:0045085) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.2 | 0.6 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.2 | 1.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 2.4 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.2 | 1.6 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.6 | GO:1904749 | rRNA export from nucleus(GO:0006407) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.1 | 0.9 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.1 | 2.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 1.0 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 2.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.3 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 0.1 | 0.2 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.1 | 1.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.9 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 0.4 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.0 | 0.3 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.0 | 1.6 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.6 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 4.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 1.2 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 2.4 | GO:0046888 | negative regulation of hormone secretion(GO:0046888) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.2 | GO:1990795 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.4 | 2.1 | GO:0005861 | troponin complex(GO:0005861) |
| 0.3 | 4.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.3 | 4.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 1.2 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.2 | 2.9 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.6 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 1.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 2.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 5.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.2 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 2.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.9 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.7 | 2.1 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.5 | 1.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.4 | 3.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.3 | 1.1 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.2 | 4.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 2.2 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 0.9 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 2.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 1.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.1 | 1.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.4 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 0.6 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.1 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 3.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 3.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.9 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.0 | 3.6 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 2.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 4.1 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 0.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 1.7 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 2.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
