Motif ID: Foxp1_Foxj2

Z-value: 1.722

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.957.6e-30Click!
Foxp1mm10_v2_chr6_-_99266494_992665400.392.1e-03Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 51.929 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr14_-_51913393 24.904 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr2_+_136713444 18.813 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr8_+_66386292 17.594 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr18_+_69344503 17.302 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr15_-_66969616 16.230 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr5_+_122643878 16.059 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr4_-_151108244 15.565 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr9_-_121495678 14.959 ENSMUST00000035120.4
 Cck
cholecystokinin
chr16_-_4880284 14.690 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr7_+_16310412 13.981 ENSMUST00000136781.1
 Bbc3
BCL2 binding component 3
chr15_-_58214882 13.833 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr17_+_35076902 13.608 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr6_-_148444336 13.543 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr6_-_58907120 13.211 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr4_-_87806296 12.391 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr16_+_91269759 12.056 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr9_-_40455670 12.018 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr19_-_34255325 11.874 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr17_+_70522083 11.857 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 401 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.7 52.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.3 29.8 GO:0070842 aggresome assembly(GO:0070842)
1.8 28.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.6 25.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.9 25.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.1 24.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.3 24.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
2.4 23.7 GO:0042118 endothelial cell activation(GO:0042118)
1.0 22.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 22.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
1.1 21.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.7 20.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.9 20.4 GO:0042572 retinol metabolic process(GO:0042572)
1.8 19.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
1.8 18.3 GO:0007379 segment specification(GO:0007379)
1.2 18.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.5 18.3 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
1.8 17.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.2 17.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
5.5 16.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 82.7 GO:0060076 excitatory synapse(GO:0060076)
0.1 49.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.9 28.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
2.5 27.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 24.2 GO:0045202 synapse(GO:0045202)
0.1 22.4 GO:0030425 dendrite(GO:0030425)
0.3 22.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 20.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 20.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
4.7 18.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.3 17.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.4 16.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 16.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 16.6 GO:0005783 endoplasmic reticulum(GO:0005783)
1.1 16.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
1.6 15.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 15.9 GO:0097060 synaptic membrane(GO:0097060)
0.3 15.8 GO:0031941 filamentous actin(GO:0031941)
1.1 15.0 GO:0043203 axon hillock(GO:0043203)
0.4 14.7 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 263 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 40.2 GO:0017124 SH3 domain binding(GO:0017124)
1.3 30.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 22.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
5.6 22.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 21.4 GO:0045296 cadherin binding(GO:0045296)
3.0 21.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 20.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
3.3 19.9 GO:0032051 clathrin light chain binding(GO:0032051)
6.5 19.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.0 19.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 16.9 GO:0017137 Rab GTPase binding(GO:0017137)
1.7 16.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 16.4 GO:0051117 ATPase binding(GO:0051117)
2.7 16.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.4 13.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 13.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
2.7 13.5 GO:0042895 antibiotic transporter activity(GO:0042895)
0.3 13.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.5 12.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.9 12.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)