Motif ID: Gata2_Gata1

Z-value: 1.408

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata1mm10_v2_chrX_-_7967817_79679100.783.9e-13Click!
Gata2mm10_v2_chr6_+_88198656_881986750.383.1e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_32276400 52.845 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 45.945 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr3_-_154330543 20.675 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr19_-_42202150 18.336 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr3_+_135825788 16.659 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr7_-_99238564 16.222 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chrX_+_150547375 13.953 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr7_-_139582790 12.722 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr9_-_32541589 12.016 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr17_+_36869567 11.915 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr13_+_38345716 11.084 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr2_-_153241402 11.018 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr13_-_116309639 10.277 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr7_-_4522427 10.170 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr6_+_30541582 10.163 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr17_-_84682932 10.160 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr9_-_44342332 9.540 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr11_+_90030295 9.334 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr1_+_45311538 9.312 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr4_-_46404224 9.234 ENSMUST00000107764.2
Hemgn
hemogen
chr3_+_135826075 8.560 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr4_+_11579647 8.535 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr15_-_103251465 8.500 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chrX_-_107403295 8.020 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr4_+_41760454 7.813 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr7_-_100662315 7.636 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr4_-_59438633 7.236 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr3_+_89136572 6.817 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr10_+_80019621 6.708 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr11_+_95337012 6.537 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr16_-_95459245 6.474 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr7_-_4522794 6.435 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr6_+_125552948 6.397 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr10_-_80421847 6.316 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr19_+_58670358 5.956 ENSMUST00000057270.7
Pnlip
pancreatic lipase
chr7_-_100662414 5.873 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_134864536 5.734 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr3_+_89136133 5.680 ENSMUST00000047111.6
Pklr
pyruvate kinase liver and red blood cell
chr3_-_63851251 5.591 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr2_-_121037048 5.565 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chr12_-_10900296 5.448 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chrX_+_73757069 5.409 ENSMUST00000002079.6
Plxnb3
plexin B3
chr1_-_162866502 5.390 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr11_-_102469839 5.095 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr3_+_106113229 4.900 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr2_+_70474923 4.851 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr2_+_103957976 4.837 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr7_+_110627650 4.806 ENSMUST00000033054.8
Adm
adrenomedullin
chr2_+_72476159 4.805 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr2_+_72476225 4.804 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr17_-_85688252 4.725 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr17_+_71204647 4.629 ENSMUST00000126681.1
Lpin2
lipin 2
chr5_-_125294107 4.626 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr14_-_54577578 4.296 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr19_+_24875679 4.060 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr8_+_84901928 3.833 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr2_+_26583858 3.671 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr16_+_45093611 3.524 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr15_-_83170498 3.289 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr15_-_50890396 3.092 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr15_-_83170168 3.067 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr19_-_7019423 3.051 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr9_-_21963568 3.018 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr3_-_94473591 3.005 ENSMUST00000029785.3
Riiad1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr1_+_75450699 2.987 ENSMUST00000037708.9
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr2_+_85037212 2.983 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr11_-_64436653 2.832 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr3_-_84479418 2.775 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr16_+_45094036 2.753 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr1_+_6730051 2.621 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr7_+_110773658 2.614 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr1_+_75450436 2.600 ENSMUST00000113577.1
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr3_-_138131356 2.573 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr1_+_6730135 2.480 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr18_+_57142782 2.464 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr5_-_121836852 2.439 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr15_+_76904070 2.422 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr10_-_13388830 2.334 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr11_-_5898771 2.325 ENSMUST00000102921.3
Myl7
myosin, light polypeptide 7, regulatory
chr3_+_79884576 2.293 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr1_+_135818593 2.285 ENSMUST00000038760.8
Lad1
ladinin
chr3_+_79884496 2.253 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr9_+_44069421 2.241 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr2_-_25224653 2.230 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr4_+_117096049 2.227 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr3_+_133338936 2.213 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr14_-_34503323 2.194 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr8_+_84908731 2.126 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr8_+_46490968 2.077 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr2_+_85037448 2.058 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr2_-_77170592 2.023 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr2_+_164403194 1.965 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chrX_+_99975570 1.844 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr8_+_84908680 1.782 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr10_+_61648552 1.765 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr5_+_24364804 1.763 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr13_-_91388079 1.734 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr1_+_172341197 1.713 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_84701430 1.701 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr5_+_42067960 1.654 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr2_+_169632996 1.650 ENSMUST00000109159.2
Tshz2
teashirt zinc finger family member 2
chr6_-_136941494 1.618 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr8_+_84908560 1.608 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr9_+_109832998 1.605 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr3_+_90072641 1.576 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr16_-_44016387 1.568 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chrX_-_18461371 1.514 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr11_-_26591729 1.512 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr6_+_15185203 1.452 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr1_-_82586781 1.317 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr3_-_146839365 1.316 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr18_+_76059458 1.293 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C
chr5_-_121836810 1.287 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr6_-_71632897 1.226 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr15_-_98607611 1.222 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr9_+_44379536 1.174 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr5_-_13121766 1.120 ENSMUST00000078246.4
Gm10108
predicted pseudogene 10108
chr6_-_136941887 1.076 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_136941694 1.074 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chrX_+_10485121 1.059 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr5_+_64812336 1.026 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr15_+_80623499 1.014 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr9_+_44379490 1.009 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr19_-_10482874 1.001 ENSMUST00000038842.3
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr4_-_119190005 0.937 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chrM_+_5319 0.891 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr1_-_14310198 0.887 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr10_+_5593718 0.868 ENSMUST00000051809.8
Myct1
myc target 1
chr4_+_124802543 0.832 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr11_+_118428493 0.828 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr3_+_79885930 0.816 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr19_+_10015016 0.762 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chr16_+_58670208 0.761 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr17_+_46650328 0.740 ENSMUST00000043464.7
Cul7
cullin 7
chr11_+_73047783 0.690 ENSMUST00000021135.3
1200014J11Rik
RIKEN cDNA 1200014J11 gene
chr4_-_14621669 0.626 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr18_-_43477764 0.620 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr10_+_90576678 0.606 ENSMUST00000182284.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_4325205 0.566 ENSMUST00000127460.1
ENSMUST00000136191.1
ENSMUST00000069762.9
ENSMUST00000098949.4
Ccl25

Ccl25

chemokine (C-C motif) ligand 25

chemokine (C-C motif) ligand 25

chr10_+_90576252 0.555 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr14_+_45329815 0.545 ENSMUST00000022380.7
Psmc6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr5_+_64159429 0.367 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr11_+_70639118 0.360 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr7_-_119895446 0.339 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr8_-_4325096 0.306 ENSMUST00000098950.4
Elavl1
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr8_+_105636509 0.250 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr10_-_83648631 0.225 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr10_-_115185015 0.221 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr19_-_43524462 0.160 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr13_-_18031616 0.154 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr10_+_90576570 0.129 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr3_-_20242173 0.095 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr10_-_14718191 0.079 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr11_+_97801917 0.052 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr10_+_90576872 0.021 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr1_+_165788681 0.017 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.8 98.8 GO:0015671 oxygen transport(GO:0015671)
6.1 18.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
3.4 10.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
3.4 10.2 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
2.8 16.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
2.5 25.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
2.4 16.8 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
2.1 12.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.9 9.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.8 16.4 GO:0006071 glycerol metabolic process(GO:0006071)
1.8 12.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.5 4.6 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
1.5 6.0 GO:0030299 intestinal cholesterol absorption(GO:0030299)
1.4 14.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.4 5.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
1.3 8.0 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.3 6.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
1.3 2.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.2 4.7 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
1.1 6.3 GO:0002326 B cell lineage commitment(GO:0002326)
1.0 9.5 GO:0018065 protein-cofactor linkage(GO:0018065)
0.9 4.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 8.5 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.8 10.8 GO:0046697 decidualization(GO:0046697)
0.8 3.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.7 11.0 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.7 2.2 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352)
0.6 2.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 1.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.6 10.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 14.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.6 1.8 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.6 1.7 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.6 2.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 5.4 GO:0009404 toxin metabolic process(GO:0009404)
0.5 3.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.5 12.0 GO:0035855 megakaryocyte development(GO:0035855)
0.4 4.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 1.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 1.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.4 5.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.4 3.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 2.6 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.3 2.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.3 20.7 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.3 4.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.7 GO:0001955 blood vessel maturation(GO:0001955)
0.2 4.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.2 1.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 0.9 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.2 1.6 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 1.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.6 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 2.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 3.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 3.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 11.4 GO:0030168 platelet activation(GO:0030168)
0.1 6.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 2.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 6.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.0 GO:0051642 centrosome localization(GO:0051642)
0.1 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 5.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 5.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1901162 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586) serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 1.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 98.8 GO:0005833 hemoglobin complex(GO:0005833)
3.4 20.7 GO:0001674 female germ cell nucleus(GO:0001674)
3.3 16.6 GO:0005861 troponin complex(GO:0005861)
1.3 6.4 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 10.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.7 9.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 8.4 GO:0031528 microvillus membrane(GO:0031528)
0.5 5.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 1.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 5.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 0.7 GO:1990393 3M complex(GO:1990393)
0.2 2.2 GO:0045298 tubulin complex(GO:0045298)
0.2 6.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.9 GO:0002102 podosome(GO:0002102)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 7.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 9.3 GO:0043204 perikaryon(GO:0043204)
0.1 4.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 8.2 GO:0000793 condensed chromosome(GO:0000793)
0.1 14.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.7 GO:0031672 A band(GO:0031672)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 8.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 6.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 3.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 10.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 33.3 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
19.8 98.8 GO:0005344 oxygen transporter activity(GO:0005344)
5.5 16.6 GO:0030172 troponin C binding(GO:0030172)
5.4 16.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
4.2 12.5 GO:0004743 pyruvate kinase activity(GO:0004743)
2.0 7.8 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
1.8 5.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.6 9.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.5 4.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
1.5 4.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.1 11.1 GO:0070700 BMP receptor binding(GO:0070700)
1.1 5.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.1 6.3 GO:0070644 vitamin D response element binding(GO:0070644)
1.0 5.1 GO:0070051 fibrinogen binding(GO:0070051)
0.9 25.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.9 14.0 GO:0016594 glycine binding(GO:0016594)
0.8 18.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.8 4.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.7 2.2 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.7 6.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.7 6.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.7 2.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.6 9.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 5.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.6 1.8 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.6 1.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.6 10.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 6.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 3.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 5.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.4 2.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 2.2 GO:0098821 BMP receptor activity(GO:0098821)
0.4 4.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 15.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 5.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 5.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 6.3 GO:0001968 fibronectin binding(GO:0001968)
0.2 8.5 GO:0050699 WW domain binding(GO:0050699)
0.2 8.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 5.6 GO:0005272 sodium channel activity(GO:0005272)
0.1 2.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 12.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 3.7 GO:0005112 Notch binding(GO:0005112)
0.1 11.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 2.2 GO:0030332 cyclin binding(GO:0030332)
0.1 3.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 13.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 3.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 12.5 GO:0003682 chromatin binding(GO:0003682)
0.0 4.8 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 21.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)