Motif ID: Gata4

Z-value: 0.781


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32276400 11.306 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 10.352 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr4_+_13751297 9.379 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_102010138 8.765 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr1_+_45311538 3.932 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr3_+_96596628 3.830 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr8_+_45628176 3.705 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr16_-_34263179 3.620 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr8_+_45627946 3.496 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 3.466 ENSMUST00000134321.1
ENSMUST00000135336.1
 Sorbs2

sorbin and SH3 domain containing 2

chr16_-_34262830 3.380 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr1_-_56969864 3.352 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr2_+_65845833 3.052 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_-_56969827 3.030 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr16_-_34262945 3.016 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr17_-_84682932 2.800 ENSMUST00000066175.3
 Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr1_-_132367879 2.711 ENSMUST00000142609.1
 Tmcc2
transmembrane and coiled-coil domains 2
chr7_-_99238564 2.702 ENSMUST00000064231.7
 Mogat2
monoacylglycerol O-acyltransferase 2
chr8_+_45658273 2.618 ENSMUST00000153798.1
 Sorbs2
sorbin and SH3 domain containing 2
chr7_-_98112618 2.532 ENSMUST00000153657.1
 Myo7a
myosin VIIA

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 21.7 GO:0015671 oxygen transport(GO:0015671)
0.5 16.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.3 10.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 9.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.3 8.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.4 6.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 5.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.5 GO:0008585 female gonad development(GO:0008585)
0.4 4.3 GO:0007379 segment specification(GO:0007379)
0.1 4.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.8 3.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 3.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.9 2.8 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.4 2.7 GO:0006071 glycerol metabolic process(GO:0006071)
0.3 2.5 GO:0050957 equilibrioception(GO:0050957)
0.2 2.4 GO:0021542 dentate gyrus development(GO:0021542)
0.2 2.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 2.2 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 21.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 20.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 9.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 7.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 4.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 3.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 3.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.3 2.8 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.2 2.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923)
0.4 2.5 GO:0002139 stereocilia coupling link(GO:0002139)
0.4 2.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.4 GO:0030427 site of polarized growth(GO:0030427)
0.4 2.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 21.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 16.6 GO:0044822 poly(A) RNA binding(GO:0044822)
0.1 13.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 11.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 10.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 4.5 GO:0003682 chromatin binding(GO:0003682)
0.4 4.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3 3.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 3.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 3.0 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 3.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 2.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.9 2.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 2.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.2 GO:0016594 glycine binding(GO:0016594)
0.4 2.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 2.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 1.9 GO:0004743 pyruvate kinase activity(GO:0004743)