Motif ID: Gbx2
Z-value: 0.491
Transcription factors associated with Gbx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gbx2 | ENSMUSG00000034486.7 | Gbx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gbx2 | mm10_v2_chr1_-_89933290_89933290 | -0.02 | 9.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 6.2 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.6 | 2.6 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.6 | 2.6 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.6 | 1.9 | GO:0036292 | DNA rewinding(GO:0036292) |
0.6 | 4.6 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.4 | 1.3 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255) |
0.4 | 2.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.4 | 1.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.4 | 1.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.3 | 2.0 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.2 | 0.7 | GO:0009193 | pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048) |
0.2 | 0.6 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.2 | 1.2 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
0.2 | 2.1 | GO:0061032 | chorio-allantoic fusion(GO:0060710) visceral serous pericardium development(GO:0061032) |
0.2 | 1.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.2 | 4.6 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.1 | 0.7 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
0.1 | 0.9 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
0.1 | 2.7 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
0.1 | 0.7 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
0.1 | 1.7 | GO:0080111 | DNA demethylation(GO:0080111) |
0.1 | 0.3 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.1 | 0.5 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
0.0 | 0.5 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
0.0 | 0.5 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482) |
0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 2.5 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.0 | 0.6 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.2 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.0 | 0.7 | GO:0006400 | tRNA modification(GO:0006400) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.6 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.3 | 1.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.3 | 2.5 | GO:0070652 | HAUS complex(GO:0070652) |
0.3 | 2.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.2 | 1.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 2.1 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 1.1 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
0.1 | 1.7 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 1.9 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.0 | 3.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.9 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.3 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.3 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 1.1 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.5 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 6.2 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 2.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 5.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 1.1 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.6 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.5 | 2.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.4 | 2.6 | GO:0000150 | recombinase activity(GO:0000150) |
0.3 | 1.9 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.3 | 1.2 | GO:0008142 | oxysterol binding(GO:0008142) |
0.3 | 2.6 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.2 | 1.9 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.1 | 0.5 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
0.1 | 0.5 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 1.3 | GO:0032557 | pyrimidine ribonucleotide binding(GO:0032557) |
0.1 | 2.0 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 4.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 0.7 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.1 | 2.3 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 0.9 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.1 | 0.3 | GO:0031403 | lithium ion binding(GO:0031403) |
0.1 | 0.5 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.1 | 0.7 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.5 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
0.1 | 0.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.1 | 1.7 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
0.0 | 0.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 1.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 1.1 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.0 | 0.3 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.2 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 6.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 1.9 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 1.1 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 0.7 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.6 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |